Results 31 to 40 of about 13,087 (187)
The Scientific World Journal, 2010 The diabetes-associated human islet amyloid polypeptide (IAPP) is a 37-amino-acid peptide that forms fibrils in vitro and in vivo. Human IAPP fibrils are toxic in a similar manner to Alzheimer's amyloid-β (Aβ) and prion protein (PrP) fibrils.
Nathaniel G. N. Milton, J. Robin Harris
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Inhibition of IAPP and IAPP(20−29) Fibrillation by Polymeric Nanoparticles [PDF]
, 2016 The fibrillation process of the islet amyloid polypeptide (IAPP) and its fragment (IAPP(20−29)) was studied by means of Thioflavin T (ThT) fluorescence and transmission electron microscopy in the absence and presence of N-isopropylacrylamide:N-tert ...
I. Lynch (2315122) +3 more
core +1 more source
Upsala Journal of Medical Sciences, 2017 Background: Enhanced IAPP production may contribute to islet amyloid formation in type 2 diabetes. The objective of this study was to determine the effects of the saturated fatty acid palmitate on IAPP levels in human β-cells.
Camilla Krizhanovskii +4 more
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Leaftronics: Bio‐Fractal Scaffolds From Leaf Venation for Low‐Waste Electronics
Advanced Materials, EarlyView.“Leaftronics” transforms naturally evolved leaf venation into quasi‐fractal scaffolds for sustainable electronics. Polymer‐infiltrated leaf skeletons can be used to fabricate ultra‐smooth, reflow‐ and thin‐film‐compatible decomposable substrates, while making the same lignocellulose networks conducting results in flexible transparent electrodes.
Rakesh Rajendran Nair +3 more
wiley +1 more source
PLoS ONE, 2019 The biologically active pancreatic hormone peptide islet amyloid polypeptide (IAPP) regulates brain functions such as appetite and cognition. It also plays a role in clearance of amyloid beta (Aβ), a peptide implicated in the dementia disorder Alzheimer ...
Nina Schultz +6 more
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Islet Amyloid Polypeptide: A Partner in Crime With Aβ in the Pathology of Alzheimer's Disease
Frontiers in Molecular Neuroscience, 2020 Diabetes affects hundreds of millions of patients worldwide. Despite the advances in understanding the disease and therapeutic options, it remains a leading cause of death and of comorbidities globally.
Ana F. Raimundo +8 more
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Advanced Materials Technologies, EarlyView.A fully organic UV threshold dosimeter is developed by exploiting the oxygen‐sensitive room‐temperature phosphorescence of a purely organic emitter in a polymer matrix. Upon reaching a specific cumulative UV dose, photochemical oxygen depletion triggers a sharp, high‐contrast emission.
Tim Achenbach +3 more
wiley +1 more source
Effects of Protein Corona on IAPP Amyloid Aggregation, Fibril Remodelling, and Cytotoxicity
Scientific Reports, 2017 Aggregation of islet amyloid polypeptide (IAPP), a peptide hormone co-synthesized and co-stored with insulin in pancreatic cells and also co-secreted to the circulation, is associated with beta-cell death in type-2 diabetes (T2D). In T2D patients IAPP is
Emily H. Pilkington +7 more
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Advanced Materials Technologies, EarlyView.Programmable luminescent tags based on organic room‐temperature phosphorescence are shown to be governed by oxygen incorporation during fabrication. Oxygen‐free processing enables immediate phosphorescence activation, controlled thermal preconditioning, and tunable activation doses.
Lucy Winkler +2 more
wiley +1 more source
Advanced Electronic Materials, EarlyView.This work explores how colloidal CuInSe2 nanocrystals form functional field‐effect transistors when their native ligands are replaced with short inorganic species that promote charge transport. By systematically adjusting nanocrystal dimensions, surface treatments, film characteristics, and device architecture, the study maps the resulting electronic ...
Nadia Günther +8 more
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