Results 81 to 90 of about 417,281 (310)

Comprehensive In Vitro Profiling Demonstrates Successful Immune Evasion of Bioengineered Immune‐Shielded Heart Valves

Advanced Healthcare Materials, EarlyView.
Living donor heart valves offer superior durability for pediatric patients but trigger immune rejection. Lentiviral delivery of viral immune‐evasion genes US2 and Serpin b9 into donor valve cells and valve tissue suppresses HLA expression, reduces PBMC clustering and cytotoxic killing, and induces transcriptional immune‐tolerance programs, paving the ...
Abraham van Wijk, Leanne Van den Berg, Isa B. M. Velraeds, Valentina Osorio Zuluaga, Emma T. M. Peereboom, Martijn J. W. E. Rabelink, Arnaud Zaldumbide, Rob C. Hoeben, Marie‐Jose T. H. Goumans, Eric Spierings, Carlijn V. C. Bouten, Marijn C. Peters   +11 more
wiley   +1 more source

AKTIVITAS ANTIOKSIDAN EKSTRAK DAUN KELOR (Moringa oleifera Lam.) DAN BUAH BIT (Beta vulgaris L.) SEBAGAI BAHAN TAMBAHAN MINUMAN SUPLEMEN

Jurnal Kimia Riset, 2020
Minuman suplemen merupakan produk pelengkap kebutuhan zat gizi makanan yang mempunyai nilai gizi dan atau efek fisiologis dalam jumlah terkonsentrasi. Bahan tambahan dalam minuman suplemen dapat diperoleh dari tanaman yang memiliki aktivitas antioksidan.
, Tukiran, Mauren Gita Miranti, Idah Dianawati, fauzia indah sabila   +3 more
doaj   +1 more source

Combining IC50 or Ki Values From Different Sources is a Source of Significant Noise [PDF]

As part of the ongoing quest to find or construct large data sets for use in validating new machine learning (ML) approaches for bioactivity prediction, it has become distressingly common for researchers to combine literature IC50 data generated using ...
Sereina, Riniker, Gregory A., Landrum
core   +2 more sources

Charge‐Reversed Lipid Nanoparticles Enable Encapsulation of Pt2L4 Nanocages for In vivo Anti‐Cancer Treatment

Advanced Materials, EarlyView.
Charge‐reversed lipid nanoparticles (revLNPs) enable efficient encapsulation and delivery of cationic Pt2L4 nanocages. Encapsulation preserves potent anticancer activity while improving circulation, reducing vascular leakage, and promoting favorable biodistribution in vivo.
Renzo A. Knol, Bochuan Hu, Eduard O. Bobylev, Martina Farber, Petrus C. M. Laan, Thomas J. F. Kock, Bauke Fontein, Johanna Erbani, Oscar Escalona‐Rayo, Seline S. Roose, Tom Keijer, Gabriel Forn‐Cuní, B. Ewa Snaar‐Jagalska, Leila Akkari, Joost N. H. Reek, Alexander Kros, Dennis Aschmann   +16 more
wiley   +1 more source

An investigation into the total phenolic compounds extracted from Perilla frutescens (L.) Britt leaves and their application on blood sugar regulation

Tạp chí Khoa học và Công nghệ
This study investigated the extraction of total phenolic compounds from Perilla frutescens (L.) Britt leaves collected in Tuy Loan, Danang City, Vietnam.
Minh Nguyet Thi NGUYEN, Thuy Trang Thi PHAM, Lam Huu NGUYEN, Long Van Thanh LUU, Duyen Thai HA   +4 more
doaj   +1 more source

IC50 values of BRD3308 and SAHA for HDACs 1–9.

, 2014
IC50 values of BRD3308 and SAHA for HDACs 1–9.
Kirston M. Barton (618002), Amy S. Espeseth (226760), Edward B. Holson (445664), Jennifer Gale (445658), Yan-ling Zhang (5660299), David M. Margolis (244046), Nancie M. Archin (366945), Florence F. Wagner (445656), Kara S. Keedy (618003)   +8 more
core   +1 more source

Symptom impact on ACE2 IC50 in pre-vaccinated participants.

, 2022
Comparisons were made in pre-vaccinated participant samples (n = 41) between median ACE2 IC50 and anosmia and ageusia, cough, and fever presence and absence.
Ajay Nirula (662876), Jennifer Brothers (13767131), Robert J. Benschop (9512271), Gregory Huhn (7327478), Sheena Gillani (13767137), James Wilson (302768), Sharon Welbel (13767134), Josh Poorbaugh (12263578), Stephanie Beasley (12263587), Lin Zhang (8926), Kody Keckler (13767143), Kathleen M. Weber (7923173), Ralph Morack (13767140)   +12 more
core   +1 more source

Linking Polyelectrolyte Modification and Enzyme‐Catalyzed Phenolic Acid Functionalization of Cellulose Fiber for Functional Foams

Advanced Materials Technologies, EarlyView.
Cellulose fibers functionalized using cationic poly(Dimethyldiallylammonium chloride) (polyDADMAC) and laccase‐mediated ferulic acid system are processed into foams using different surfactants (Anionic, cationic, and non‐ionic). Fiber–surfactant interactions influence foam stabilization and porous structure formation during convective drying, producing
Abirami Senthil, Sara Wallstén, Paul Christakopoulos, Ulrika Rova, Io Antonopoulou   +4 more
wiley   +1 more source

ANTIPLASMODIAL AND ANTISALMONELLA ACTIVITIES OF PHENOLIC COMPOUND FROM ROUREA COCCINEA BENTH (CONNARACEAE)

Scientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry
The leaves extract of Rourea coccinea was fractionated, following the bioguided method, to give one phenolic compound named 1-caffeoylquinic acid lactone (1-CQL) (1), isolated from this plant for the first time, and the 3-O-β-D-glucopyranoside of ...
BASILE GOUETI , WILLIAM FEUDJOU , BÉNÉDICTA KPADONOU-KPOVIESSI , BARDIEU ATCHADE , SERONDO UWIKUNDA , LÉON AHOUSSI , JOACHIM GBENOU , SALOMÉ KPOVIESSI   +7 more
doaj  

Determination of Polyphenol Compounds in Clinacanthus nutans and Their Potential as Antioxidants

Biotropika: Journal of Tropical Biology
Free radicals can cause oxidative damage if they are produced in excess amounts in the body. To prevent this, the work of endogenous antioxidants needs to be supported by safe and effective exogenous antioxidants.
Nashi Widodo, Salma Wahid Marseti, Yuslinda Annisa, Fairuz Sarah Kamila, Nuraini Rosyadah, Muhaimin Rifa’i   +5 more
doaj   +1 more source