Results 71 to 80 of about 288,159 (307)
Determination of Polyphenol Compounds in Clinacanthus nutans and Their Potential as Antioxidants
Biotropika: Journal of Tropical BiologyFree radicals can cause oxidative damage if they are produced in excess amounts in the body. To prevent this, the work of endogenous antioxidants needs to be supported by safe and effective exogenous antioxidants.
Nashi Widodo +5 more
doaj +1 more source
Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy
Advanced Healthcare Materials, EarlyView.Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima +15 more
wiley +1 more source
International Journal of Secondary MetaboliteThe Aristolochia philippinensis Warb. (Aristolochiaceae) is commonly used in traditional medicine among indigenous people in the Philippines. The leaves of A.
Eddie Mondejar, Vanessa Grace Narvasa
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Dual acidic pH‐responsive degradable e‐spun nanofibrous mats crosslinked with acid‐labile imine and boronic ester linkages that exhibit rapid degradation and enhanced release of encapsulated anticancer drugs through their acid‐catalyzed hydrolysis and their doxorubicin‐loaded mats having desired antitumoral activity and hemocompatibility, as promising ...
Sofia Nieves Casillas‐Popova +4 more
wiley +1 more source
Advanced Materials, EarlyView.Bioorthogonal chemistry was applied to intracellularly photoactivate Doxorubicin (Dox) using gold nanostars (AuNSt) and near‐infrared (NIR) light. Two prodrugs were used: one photoactivatable, masked with 2‐nitrobenzyl carbamate (proDox1) and another photolabile, masked with 2‐nitrobenzyl diol (proDox2), which was attached to the AuNSt surface.
Juan José Esteve‐Moreno +15 more
wiley +1 more source
Scientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food IndustryThe leaves extract of Rourea coccinea was fractionated, following the bioguided method, to give one phenolic compound named 1-caffeoylquinic acid lactone (1-CQL) (1), isolated from this plant for the first time, and the 3-O-β-D-glucopyranoside of ...
BASILE GOUETI +7 more
doaj
مجله علمی دانشگاه علوم پزشکی کردستان, 2018 Background and Aim: Vulvovaginal candidiasis and trichomoniasis account for at least 50 percent of all cases of vaginal infections. The main drugs used to treat these infections have numerous side effects and drug resistance to them is on the rise.
Mina Ebrahimi +3 more
doaj
Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract
Advanced Robotics Research, EarlyView.We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis +7 more
wiley +1 more source
Journal of PharmacopunctureObjectives: To determine growth inhibitory and anti-cancer effects of Cannabigerol (CBG) in human colorectal cancer cells.Methods: Anti-proliferative effect of CBG was examined using MTT assay and two colorectal cancer cells (SW480 and LoVo cells).
Ju-Hee Park +7 more
doaj +1 more source
Advanced Science, EarlyView.Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai +15 more
wiley +1 more source