Results 71 to 80 of about 417,281 (310)

IC50 of hep-ATIII in different liposome formulations.

, 2012
IC50 of hep-ATIII in different liposome formulations.
Angela Carville (122470), Corinne Luedemann (122468), Ralf Geiben-Lynn (122473), James B. Whitney (122465), Robert Steen (66867), Mohammed Asmal (122461), Norman L. Letvin (122471)   +6 more
core   +1 more source

IC50 determination ixazomib [n = 2] for TOM-1 and BV-173.

, 2022
Ph+ cells BV-173 and TOM-1 were treated with DMSO and bortezomib at day 0, CCK8 assay was performed at day 1,2 and 3. The IC50 is depicted in a non-linear regression curve with the point of inflections representing the respective IC50.
Margherita Vieri (3482504), Mirle Schemionek (151019), Azam Salimi (13003755), Kema Marlen Schroeder (13003758), Behzad Kharabi Masouleh (13003770), Steffen Koschmieder (106779), Saskia Maletzke (13003764), Tim H. Brümmendorf (9263733), Iris Appelmann (365795)   +8 more
core   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Isolation, characterization and antioxidant activity of fibrinogen-like protein-1 from serum and synovial fluid of patients with rheumatoid arthritis [PDF]

The Ukrainian Biochemical Journal
Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation and oxidative stress. Fibrinogen-like protein-1 (FGL1) has been implicated in immune regulation, but its antioxidant role under inflammatory conditions remains ...
Abdulsattar J. Abdullah, Zahraa M. A. Hamodat   +1 more
doaj   +1 more source

PDAC IC50 when treated with gefitinib or cetuximab.

, 2019
PDAC IC50 when treated with gefitinib or cetuximab.
Ethan Poteet (125162), Qizhi Yao (413878), George Van Buren (6524021), Changyi Chen (413877), Zhengdong Liang (502738), Dongliang Liu (653854)   +5 more
core   +1 more source

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

Anticancer Efficacy of 5-Fluorouracil-Loaded Chitin Nanohydrogel in Enhanced Skin Cancer Therapy

BIO Integration
The pyrimidine analog 5-flurouracil (5-FU) is effective against solid tumors. However, the half-life of intravenously administered 5-FU is less than 20 min, and the compound is quickly eliminated and shows systemic toxicity.
Yuvraj D. Dange, Vijay R. Salunkhe, Sandip M. Honmane, Pradnya S. Marale   +3 more
doaj   +1 more source

Average allopurinol IC50 values of promastigote and axenic amastigotes.

, 2016
Average allopurinol IC50 values found for promastigotes and axenic amastigotes of isolates from dogs in the study groups. Numbers in labels represent group mean ± STDEV.
Daniel Yasur-Landau (843674), Lior David (22328), Gad Baneth (254948), Charles L. Jaffe (254946)   +3 more
core   +1 more source

Advances in 3D Bioprinting for Breast Cancer Modeling: Tumor Microenvironment, Metastasis, and Drug Screening

Advanced Healthcare Materials, EarlyView.
Three‐dimensional bioprinting transforms breast cancer modeling from simple constructs into spatially organized, multicellular, perfused, and patient‐derived platforms. This review shows how bioinks, cellular composition, architecture, and flow govern tumor behavior and drug response, while revealing why complexity alone is insufficient without ...
Mustafa Nakipoglu, Mahboobeh Mahmoodi, Ehsanul Hoque Apu, Fahimeh Shahabipour, Sibel Emir Diltemiz, Sanjib Saha, Halima Alem, Nureddin Ashammakhi   +7 more
wiley   +1 more source

IC50 of combination (SS1P & Enzastaurin) treatment relative to SS1P alone.

, 2013
IC50 of combination (SS1P & Enzastaurin) treatment relative to SS1P alone.
Abid R. Mattoo (468437), Ira Pastan (303807), David FitzGerald (231462)   +2 more
core   +1 more source