Results 91 to 100 of about 417,281 (310)

The antioxidants and secondary metabolites found in chicory (Cichorium intybus L.) are affected by biofertilizers, conventional fertilizers, and nano-fertilizers [PDF]

open access: yesTikrit Journal for Agricultural Sciences
In winter 2024, a field study was conducted on the wild chicory plant (Cichorium intybus L.), a medicinal species having nutritional and pharmacological properties.
Asmaa Aliwi   +2 more
doaj   +1 more source

Symptom impact on ACE2 IC50 in post-vaccinated participants.

open access: yes, 2022
Comparisons were made in post-vaccinated participant samples (n = 27) between median ACE2 IC50 and anosmia/ageusia, cough, and fever presence and absence.
Ajay Nirula (662876)   +12 more
core   +1 more source

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

open access: yesAdvanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis   +7 more
wiley   +1 more source

Phytochemical screening, antibacterial and cytotoxic activities of Aristolochia philippinensis Warb. leaf extracts

open access: yesInternational Journal of Secondary Metabolite
The Aristolochia philippinensis Warb. (Aristolochiaceae) is commonly used in traditional medicine among indigenous people in the Philippines. The leaves of A.
Eddie Mondejar, Vanessa Grace Narvasa
doaj   +1 more source

Selective Cytotoxic and Antibiofilm Activities of Pseudomonas aeruginosa Exotoxin A on HN5 Cells and Bacterial Isolates [PDF]

open access: yesBIO Web of Conferences
Pseudomonas aeruginosa produces Exotoxin A (PE), a major virulence factor that exhibits cytotoxic activity and has been investigated for its potential anticancer applications.
Ahmed Nabaa Abd Aljabar   +1 more
doaj   +1 more source

Deep Contrastive Learning for High‐Throughput Prediction of Drug Resistance Mutations from Sequences

open access: yesAdvanced Science, EarlyView.
This study presents DeepMutDTA, a deep learning framework aimed at predicting mutation‐induced changes in protein‐drug interactions and prioritizing variants potentially linked to drug resistance. Trained on large‐scale data, it incorporates SimSiam‐MuTF, a label‐aware contrastive fine‐tuning strategy that encourages separation between WT and MT ...
Xiaowen Hu   +7 more
wiley   +1 more source

The effect of acetone extract of Moringa peregrina on Trichomonas vaginalis, Candida albicans and macrophage cells in vitro.

open access: yesمجله علمی دانشگاه علوم پزشکی کردستان, 2018
Background and Aim: Vulvovaginal candidiasis and trichomoniasis account for at least 50 percent of all cases of vaginal infections. The main drugs used to treat these infections have numerous side effects and drug resistance to them is on the rise.
Mina Ebrahimi   +3 more
doaj  

Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis

open access: yesAdvanced Science, EarlyView.
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang   +9 more
wiley   +1 more source

Cannabigerol Treatment Shows Antiproliferative Activity and Causes Apoptosis of Human Colorectal Cancer Cells

open access: yesJournal of Pharmacopuncture
Objectives: To determine growth inhibitory and anti-cancer effects of Cannabigerol (CBG) in human colorectal cancer cells.Methods: Anti-proliferative effect of CBG was examined using MTT assay and two colorectal cancer cells (SW480 and LoVo cells).
Ju-Hee Park   +7 more
doaj   +1 more source

Half inhibition concentration (IC50) of candidate drugs for LoVo cells.

open access: yes, 2013
Half inhibition concentration (IC50) of candidate drugs for LoVo cells.
Hua Sui (482525)   +10 more
core   +1 more source

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