Results 11 to 20 of about 40,233 (217)

Aseptic necrosis of bone in ICR mice [PDF]

open access: yesLaboratory Animals, 1988
Aseptic bone necrosis was observed in the tibia of 23 ICR mice. Histological changes were characterized by a loss of marrow tissue with proliferation of connective tissue and bone necrosis with empty osteocytic lacunae. Focal necrosis was confined beneath the articular cartilage. Extensive necrosis was present in half or all of the epiphysis.
K, Yamasaki, C, Itakura
openaire   +2 more sources

Evaluation of acellular pertussis vaccine: comparisons among different strains of mice

open access: yesEmerging Microbes and Infections, 2023
The current study was designed to comparatively analyse the reactions of different mouse strains in response to acellular pertussis (aP) vaccine, with attempt to further provide a reference for aP vaccine evaluation.
Jie Wei   +8 more
doaj   +1 more source

Reduction of type IV collagen by upregulated miR-29 in normal elderly mouse and klotho-deficient, senescence-model mouse. [PDF]

open access: yesPLoS ONE, 2012
MicroRNA (miRNA), a small non-coding RNA that functions as a mediator in gene silencing, plays important roles in gene regulation in various vital functions and activities. Here we show that the miR-29 members are upregulated in klotho-deficient [klotho(-
Masaki Takahashi   +3 more
doaj   +1 more source

Histopathological changes of acetaminophen-induced liver injury and subsequent liver regeneration in BALB/C and ICR mice [PDF]

open access: yesVeterinary World, 2019
Background and Aim: Laboratory mice are widely used as a research model to provide insights into toxicological studies of various xenobiotic. Acetaminophen (APAP) is an antipyretic and analgesic drug that is commonly known as paracetamol, an ideal ...
Fazil Muhammad-Azam   +4 more
doaj   +1 more source

PENGARUH PEMBERIAN TUAK TERHADAP GAMBARAN HISTOPATOLOGI HATI MENCIT (Mus musculus) ICR JANTAN

open access: yesJurnal Pendidikan Matematika dan IPA, 2020
Liver damage or liver disease is caused by many factors, one of which is by consuming drinks that contain alcohol. Tuak is one of the drinks that contain alcohol.
St Aisyah Sijid   +3 more
doaj   +1 more source

Prevalence of Mouse Norovirus in Experimental Mice in Beijing

open access: yesShiyan dongwu yu bijiao yixue, 2023
ObjectiveTo investigate the infection of mouse norovirus (MNV) in experimental mice raised under natural conditions from 19 biological companies in Beijing.MethodsThe mice used in this study were randomly selected from mice produced by 19 companies, and ...
LIU Fangni   +4 more
doaj   +1 more source

Marginal Biotin Deficiency Is Teratogenic in ICR Mice [PDF]

open access: yesThe Journal of Nutrition, 2003
The incidence of marginal biotin deficiency in normal human gestation is approximately one in three. In ICR mice, maternal biotin deficiency results in cleft palate, micrognathia, microglossia and limb hypoplasia. However, the relationships among the severity of maternal biotin deficiency, fetal biotin status and malformations have not been reported ...
Donald M, Mock   +4 more
openaire   +2 more sources

Annual tendency of research papers used ICR mice as experimental animals in biomedical research fields

open access: yesLaboratory Animal Research, 2017
Institute of Cancer Research (ICR) mice have been widely used in various research fields including toxicology, oncology, pharmacology, and pharmaceutical product safety testing for decades.
Ji Eun Kim   +4 more
doaj   +1 more source

Overexpression of SGLT2 in the kidney of a P. gingivalis LPS-induced diabetic nephropathy mouse model

open access: yesBMC Nephrology, 2021
Background The overexpression of sodium-glucose cotransporter 2 (SGLT2) in diabetic kidneys has been reported. It has also been established that the diabetic glomerular endothelium expresses the toll-like receptors TLR2 and TLR4.
Koichiro Kajiwara, Yoshihiko Sawa
doaj   +1 more source

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