MISE EN EVIDENCE ET CARACTERISATION DES RECEPTEURS DE IGF-I ET DE IGF-II SUR DEUX SOUS-CLONES DE LA LIGNEE CELLULAIRE MYOBLASTIQUE C2 DE SOURIS [PDF]
A. Domeyne, C. Huré, Christian Pinset
openalex +1 more source
Sensor‐Embedded Muscle for Closed‐Loop Controllable Actuation in Proprioceptive Biohybrid Robots
Skeletal muscle tissue‐based bioactuators move in response to externally applied electrical stimuli in open‐loop control, which lacks knowledge of the actuator's state. Herein, a soft and fiber‐shaped piezoresistive mechanosensor that integrates with the soft tissue and operates in the cell culture environment is used to create the first proprioceptive
Miriam Filippi+8 more
wiley +1 more source
Monolithic Biohybrid Flexure Mechanism Actuated by Bioengineered Skeletal Muscle Tissue
A scalable, monolithic biohybrid flexure mechanism is presented, integrating engineered skeletal muscle tissue with a soft, biocompatible, hollow silicone cylinder featuring dual pillars. Muscle contraction induces bending motion upon electrical stimulation, with performance governed by the structure's flexural rigidity.
Andrea Bartolucci+13 more
wiley +1 more source
EFFECTS OF PROLONGED IGF-I TREATMENT IN CHILDREN WITH GROWTH HORMONE INSENSITIVITY SYNDROME (GHIS) [PDF]
Philippe Backeljauw+9 more
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Worth the Effort: Lessons for Discovery and Care From an Unusual Case of Gorlin Syndrome
ABSTRACT Gorlin‐Goltz Syndrome (GGS) is a rare autosomal dominant genetic disorder encompassing a diverse range of clinical manifestations, including congenital anomalies and predisposition to cancer. Pathogenic variants in PTCH1 and SUFU account for up to 79% and 6% of cases, respectively. Currently, an estimated 15%–27% of individuals with a clinical
V. Taliercio+13 more
wiley +1 more source
Insulin-like growth factor I (IGF-I) and liver cirrhosis [PDF]
Insulin-like growth factor I (IGF-I) is a polypeptide hormone secreted by multiple tissues in response to growth hormone (GH). It is partly responsible for GH activity, and also has glucose-lowering and anabolizing effects.
Conchillo, M. (M.)+2 more
core
Differential regulation of insulin-like growth factor binding protein secretion from human decidual cells by IGF-I, insulin, and relaxin. [PDF]
K.M. Thraikill+3 more
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La adición de IGF-I a los medios de fertilización in vitro y cultivo de embriones ha sido propuesta como una forma de imitar las señales maternas de la gestación temprana en el útero. El objetivo del presente estudio fue evaluar la adición
Octavio Martínez-Guerrero+2 more
doaj
Survivorship of Individuals With Double Heterozygosity for Achondroplasia and Type 2 Collagenopathy
ABSTRACT Historically, double heterozygosity, or a diagnosis of two separate, dominant genetic conditions, was often thought to be lethal in individuals with autosomal dominant skeletal dysplasias. In previously published studies of individuals with dual dysplasia diagnoses of achondroplasia and type 2 collagenopathy, infants died of respiratory ...
Valerie R. Schwartz+3 more
wiley +1 more source
Purpose To investigate the associations of serum insulin like growth factor I (IGF-I) and Osteocalcin (OC) concentrations with gestational diabetes mellitus (GDM) risk among Chinese women.
Lingling Cui+8 more
doaj +1 more source