Transfer of insulin-like growth factors I and II from plasma to lymph in young goats [PDF]
, 1992 The plasma clearance of intravenously injected '25I-labelled insulin-like growth factor I (IGFI, n = 13) and IGF-II (n = 12) and their transfer into lymph draining the foreleg of 3 5- to 8- week-old British Saanen goats was studied.
Baucells Sánchez, María Dolores +2 more
core +2 more sources
Virology Journal, 2011 Hepatocellular carcinoma is mainly associated with viral hepatitis B and C. Activation of cell growth stimulator IGF-II gene is observed in tumor formation especially in viral associated hepatocellular carcinoma.
Sarwar Muhammad T +11 more
doaj +1 more source
Cellular Physiology and Biochemistry, 2018 Background/Aims: Chronic hepatitis B virus (HBV) infection (CHB) plays a central role in the etiology of hepatocellular carcinoma (HCC). Emerging evidence implicates insulin-like growth factor (IGF)-II as a major risk factor for the growth and ...
Yuanyuan Ji +5 more
doaj +1 more source
Role of Scaffold Protein Proline-, Glutamic Acid-, and Leucine-Rich Protein 1 (PELP1) in the Modulation of Adrenocortical Cancer Cell Growth [PDF]
, 2017 PELP1 acts as an estrogen receptor (ER) coactivator that exerts an essential role in the ER's functions. ER coregulators have a critical role in the progression and response to hormonal treatment of estrogen-dependent tumors.
Avena, Paola +7 more
core +2 more sources
Extreme Hypoglycaemia in Anaplastic Large Cell Lymphoma
European Journal of Case Reports in Internal Medicine, 2017 Introduction: Hypoglycaemia associated with non-islet cell tumours (NICTH) is a rare entity in patients with extra-pancreatic malignancies, mostly attributed to large mesenchymal or epithelial tumours.
Lidor Akavia, Ilan Krauze
doaj +1 more source
Comparative Effects of Insulin‐Like Growth Factor II (IGF‐II) and IGF‐II Mutants Specific for IGF‐II/CIM6‐P or IGF‐I Receptors on in Vitro Hematopoiesis [PDF]
STEM CELLS, 1996 This report presents the results of studies investigating the effect of insulin-like growth factor II (IGF-II) on the proliferation and differentiation of CD34+ bone marrow cells in serum-substituted liquid cultures. Bone marrow cells were enriched for CD34+ cells and then placed in liquid cultures supplemented with either interleukin 3 (IL-3) or IL-3 ...
G N, Schwartz +7 more
openaire +2 more sources
Refractory hypoglycemia in a patient with functional adrenal cortical carcinoma
Endocrinology, Diabetes & Metabolism Case Reports, 2016 Adrenacarcinomas are rare, and hypoglycemic syndrome resulting from the secretion of insulin-like growth factor II (IGF-II) by these tumors have been described infrequently.
Katia Regina Marchetti +3 more
doaj +1 more source
Insulin-Like Growth Factor-II and Ischemic Stroke—A Prospective Observational Study
Life, 2021 Insulin-like growth factor-II (IGF-II) regulates prenatal brain development, but the role in adult brain function and injury is unclear. Here, we determined whether serum levels of IGF-II (s-IGF-II) are associated with mortality and functional outcome ...
Daniel Åberg +7 more
doaj +1 more source
Understanding the mechanism of insulin and insulin-like growth factor (IGF) receptor activation by IGF-II. [PDF]
PLoS ONE, 2011 BACKGROUND: Insulin-like growth factor-II (IGF-II) promotes cell proliferation and survival and plays an important role in normal fetal development and placental function.
Clair L Alvino +6 more
doaj +1 more source
Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain [PDF]
, 2016 Insulin and insulin-like growth factors I and II are closely related protein hormones. Their distinct evolution has resulted in different yet overlapping biological functions with insulin becoming a key regulator of metabolism, whereas insulin-like ...
Collinsová, Michaela +13 more
core +2 more sources