Results 41 to 50 of about 92,734 (184)

Characteristics of Hepatic IGF-II Expression and Monitored Levels of Circulating IGF-II mRNA in Metastasis of Hepatocellular Carcinoma [PDF]

open access: yesAmerican Journal of Clinical Pathology, 2010
Abstract The prognosis of hepatocellular carcinoma (HCC) remains dismal. Insulin-like growth factor II (IGF-II), a fetal growth factor, is highly expressed during HCC development. We examined serum IGF-II levels and circulating IGF-II messenger RNA (mRNA) expression and analyzed the clinicopathologic characteristics in patients with ...
Jing, Qian   +9 more
openaire   +2 more sources

CLINICAL IMPLICATIONS OF INSULIN-LIKE GROWTH FACTORS (IGF) AND IGF-BINDING PROTEINS INVESTIGATION IN PATIENTS WITH OVARIAN NEOPLASMS

open access: yesAlʹmanah Kliničeskoj Mediciny, 2016
Background: The insulin-like growth factor (IGF) signaling system plays a major role in development and progression of various malignancies including ovarian cancer, and its components are considered as potential diagnostic and prognostic markers and the
E. S. Gershteyn   +7 more
doaj   +1 more source

IGF-I receptor phosphorylation is impaired in cathepsin X-deficient prostate cancer cells [PDF]

open access: yes, 2012
The cysteine-type peptidase cathepsin X is highly upregulated in several cancers and presumably promotes tumor invasion through bypassing cellular senescence. Here, we present first evidence that the underlying mechanism may involve the regulation of the
Bunsen, Thea   +3 more
core   +1 more source

Characterization of IGF-II isoforms in binge eating disorder and its group psychological treatment. [PDF]

open access: yesPLoS ONE, 2013
Binge eating disorder (BED) affects 3.5% of the population and is characterized by binge eating for at least 2 days a week for 6 months. Treatment options include cognitive behavioral therapy, interpersonal psychotherapy, and pharmacotherapy which are ...
Giorgio Tasca   +9 more
doaj   +1 more source

Temporal expression pattern of the insulin-like growth factor II and fibroblast growth factor transcripts in avian embryogenesis [PDF]

open access: yes, 2008
In this study, the abundance of IGF-II and bFGF transcripts was estimated in the chicken embryos using the competitive RT-PCR analysis. Significant enhancements in the abundance of IGF-II mRNA were observed at stages HH1 and 5, and a new accumulation in ...
ALVARES, Lúcia Elvira   +2 more
core   +3 more sources

Influence of L-carnitine on litter characteristics from gilts harvested at day 40, 55, and 70 of gestation [PDF]

open access: yes, 2005
Swine research, 2005 is known as Swine day, 2005A total of 59 gilts were used to determine the effects of supplemental L-carnitine on reproductive performance. Experimental treatments were arranged in a 2 × 3 factorial with main effects of L-carnitine (0
Brazle, A.E.   +12 more
core   +2 more sources

Effect of iron deficiency on the expression of insulin-like growth factor-II and its receptor in neuronal and glial cells

open access: yesNeurología (English Edition), 2014
Introduction: Many studies have demonstrated that iron deficiency modifies the normal function of the central nervous system (CNS) and alters cognitive abilities.
E. Morales González   +2 more
doaj   +1 more source

Effect of Insulin-Like Growth Factor II on Protecting Myoblast Cells Against Cisplatin-Induced Apoptosis Through p70 S6 Kinase Pathway

open access: yesNeoplasia: An International Journal for Oncology Research, 2002
Insulin-like growth factor. (IGF-II) is overexpressed in a variety of human tumors and has both mitogenic and antiapoptotic activity. Although the mechanisms of IGFII-induced proliferation have been well studied, the mechanisms underlying its survival ...
Xiaolin Wan, Lee J. Helman
doaj   +1 more source

Insulin and insulin like growth factor II endocytosis and signaling via insulin receptor B [PDF]

open access: yes, 2013
Insulin and insulin-like growth factors (IGFs) act on tetrameric tyrosine kinase receptors controlling essential functions including growth, metabolism, reproduction and longevity.
Barcos, Lucía Soledad   +6 more
core   +3 more sources

Nonislet Cell Tumor Hypoglycemia in a Patient with Adrenal Cortical Carcinoma

open access: yesCase Reports in Endocrinology, 2016
Nonislet cell tumor hypoglycemia (NICTH) is a rare but serious paraneoplastic syndrome in which a tumor secretes incompletely processed precursors of insulin-like growth factor-II (IGF-II), causing hypoglycemia.
Se Won Kim   +5 more
doaj   +1 more source

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