Results 71 to 80 of about 92,734 (184)

Genetic factors and insulin secretion: gene variants in the IGF genes [PDF]

, 2004
IGFs are important regulators of pancreatic beta-cell development, growth, and maintenance. Mutations in the IGF genes have been found to be associated with type 2 diabetes, myocardial infarction, birth weight, and obesity.
Dekker, J.M. (Jacqueline), Duijn, C.M. (Cornelia) van, Fritsche, A. (Andreas), Haeften, T.W. (Timon) van, Haring, H.U., Hart, L.M. (Leen) 't, Heine, R.J. (Robert), Maassen, J.A. (Johannes), Machicao, F., Nijpels, M.G.A.A.M. (Giel), Rietveld, I. (Ingrid), Stumvoll, M. (Michael)   +11 more
core  

Common polymorphism in H19 associated with birthweight and cord blood IGF-II levels in humans [PDF]

, 2005
Background: Common genetic variation at genes that are imprinted and exclusively maternally expressed could explain the apparent maternal-specific inheritance of low birthweight reported in large family pedigrees.
ALSPAC Study Team, The, Barratt, BJ, Cordell, HJ, Dunger, DB, Ong, KK, Pembrey, ME, Petry, CJ, Reik, W, Ring, SM, Todd, JA, Wingate, D   +10 more
core  

Involvement of IGF-II receptors in the antioxidant and neuroprotective effects of IGF-II on adult cortical neuronal cultures

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2014
Insulin-like growth factor-II (IGF-II) is a naturally occurring peptide that exerts known pleiotropic effects ranging from metabolic modulation to cellular development, growth and survival. IGF-II triggers its actions by binding to and activating IGF (IGF-I and IGF-II) receptors.
Martin Montañez, E., Pavia, J., Santin, L. J., BORALDI, Federica, Estivill Torrus, G., Aguirre, J. A., Garcia Fernandez, M.   +6 more
openaire   +3 more sources

Where the wolf roams: ecological preferences and wild prey association in a changing Mediterranean landscape

Frontiers in Zoology
The wolf (Canis lupus) is a species of great conservation interest and has recently highlighted management challenges throughout Europe. Over the past 50 years, the establishment of National Parks, forest cover changes as well as the expansion of wild ...
Maria Buglione, Domenico Fulgione, Tiziano Trasmondo, Benedetta De Francesco, Gabriele de Filippo, Eleonora Rivieccio   +5 more
doaj   +1 more source

Profile and regulation of annexin II expression during early embryogenesis in cattle Perfil e regulação da expressão da anexina II durante a embriogênese em bovinos

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2007
The presence of annexin II (Ann-II) during the initial stages of bovine embryo development and the regulation of Ann-II expression by retinol and insulin-like growth factor I (IGF-I) were studied.
L.F.S. Costa, M.S.N Machado, J.F.C. Oliveira, J.C. Silva, R.S. Loguercio, P.B.D. Gonçalves   +5 more
doaj   +1 more source

Efecto neuroprotector de IGF-II en situaciones de estrés neuronal inducido por corticosterona [PDF]

, 2013
Presentado en el 15º Congreso Nacional de la SENC 2013El daño por estrés en tejido neuronal mediado por la presencia de elevados niveles de corticosterona, se relaciona con la producción de alteraciones en funciones cognitivas.
Aguirre-Gomez, Jose Angel, Estivill-Torrús, Guillermo, García-Fernández, Maria Inmaculada, Martinez-Montañez, Elisa, Pavia-Molina, Jose, Santin-Nuñez, Luis Javier   +5 more
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Zmiany w stężeniach insulinopodobnych czynników wzrostu IGF-1 i IGF-2 i białek wiążących BP-2 i BP-3 w czasie leczenia ostrej białaczki limfoblastycznej [PDF]

Pediatric Endocrinology, Diabetes and Metabolism, 2004
Cel pracy: Ocena dynamiki zmian w wartościach insulinopodobnych czynników wzrostu: IGF-1 i IGF-2 i białek wiążących: IGFBP-2 i IGFBP-3 w surowicy krwi dzieci z ostrą białaczką limfoblastyczną (ALL) w trakcie leczenia przeciwnowotworowego.
Maryna Krawczuk-Rybak, Anna Kitszel, Sławomir Wołczyński   +2 more
doaj  

Liver mitochondrial dysfunction is reverted by insulin-like growth factor II (IGF-II) in aging rats

Journal of Translational Medicine, 2011
Background Serum IGF-I and IGF-II levels decline with age. IGF-I replacement therapy reduces the impact of age in rats. We have recently reported that IGF-II is able to act, in part, as an analogous of IGF-I in aging rats reducing oxidative damage in ...
Castilla-Cortazar Inma, Guerra Lucia, Puche Juan E, Sierra Inma, Garcia-Fernandez Maria   +4 more
doaj   +1 more source

Nucleotide sequences of cDNAs encoding precursors of human insulin‐like growth factor II (IGF‐II) and an IGF‐II variant

FEBS Letters, 1985
We have isolated 3 cDNA clones encoding human IGF‐II and a variant of IGF‐II. The amino acid sequence encoded by the IGF‐II cDNA is identical to the sequence previously described [(1978) FEBS Lett. 89, 283‐286]. In the amino acid sequence predicted by the IGF‐II variant cDNA, the Ser residue 29 in the B‐domain has been replaced by an Arg‐Leu‐Pro‐Gly ...
Jansen, M., van Schaik, P.M.A., van Tol, H., Van den Brande, J.L., Sussenbach, J.S.   +4 more
openaire   +2 more sources

Association Between Cytokines and Liver Histology in Children with Nonalcoholic Fatty Liver Disease. [PDF]

, 2017
BackgroundReliable non-invasive markers to characterize inflammation, hepatocellular ballooning, and fibrosis in nonalcoholic fatty liver disease (NAFLD) are lacking.
Ann Scheimann, Anna Mae Diehl, Bradley Aouizerat, David Glidden, Emily R. Perito, Jean P. Molleston, Jeffrey B. Schwimmer, Joel E. Lavine, Karen F. Murray, Katherine P. Yates, Nathan M. Bass, null null, Philip Rosenthal, Ryan Gill, Veeral Ajmera   +14 more
core   +1 more source