IL-1 Receptor Antagonist Anakinra Inhibits the Effect of IL-1β- Mediated Osteoclast Formation by Periodontal Ligament Fibroblasts. [PDF]
Steemers E +4 more
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Clinical Significance of Combined Detection of CCL22 and IL-1 as Potential New Bronchial Inflammatory Mediators in Children's Asthma. [PDF]
Cui L, Song X, Peng Y, Shi M.
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Correction: Roles for TAB1 in regulating the IL-1-dependent phosphorylation of the TAB3 regulatory subunit and activity of the TAK1 complex. [PDF]
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Retraction Note: Emerging insights into the role of IL-1 inhibitors and colchicine for inflammation control in type 2 diabetes. [PDF]
Guan J, Abudouaini H, Lin K, Yang K.
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Impact of walking exercise intensity on cartilage IL-1, TNF-α, IL-4, MMP-13 and pain threshold in osteoarthritis rat models. [PDF]
Handono K +4 more
europepmc +1 more source
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Abstract IL-1 induces its own gene expression in human PBMC, in cultured smooth muscle and in endothelial cells. IL-1-induced IL-1 may be part of a self-amplification or an autocrine growth factor in a variety of responses, and thus the endogenous regulation of IL-1 production likely contributes to the outcome of immunologic or ...
Schindler, R, Ghezzi, P, Dinarello, C A
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IL-1 induces IL-1. III. Specific inhibition of IL-1 production by IFN-gamma.
The Journal of Immunology, 1988Abstract IL-1 possesses several biologic properties, some of which are associated with chronic inflammatory diseases. We have recently shown that IL-1 induces its own gene expression and, in the present studies, we have examined the effect of IFN-gamma on IL-1-induced IL-1 production. Whereas IFN-gamma increases the total amount of IL-1 (
Ghezzi, P, Dinarello, C A
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Articular chondrocytes secrete IL-1, express membrane IL-1, and have IL-1 inhibitory activity
Cellular Immunology, 1992Previous work from our laboratory has shown that rabbit articular chondrocytes, like macrophages, produce reactive oxygen intermediates, express Ia antigen, and can mediate immunologic functions such as antigen presentation and induction of mixed and autologous lymphocyte reactions.
K, Tiku +3 more
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