Results 201 to 210 of about 1,896,687 (246)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Elevated IL-1 Beta Plasma Levels, Altered Platelet Activation and Cardiac Remodeling Lead to Moderately Decreased LV Function in Alzheimer Transgenic Mice After Myocardial Ischemia and Reperfusion. [PDF]

J Cardiovasc Dev Dis
Donner L, Gorressen S, Fischer JW, Elvers M.   +3 more
europepmc   +1 more source

The Role of Inflammatory Biomarkers (IL-1, IL-6, TNF-α, and Alpha-Amylase) in Saliva on Post-Odontectomy Swelling: A Rapid Review. [PDF]

J Inflamm Res
Saim FI, Sjamsudin E, Najmi N.
europepmc   +1 more source

IL-1 modulation preserves biomolecular, structural and functional integrity of the somatosensory cortex after fetal inflammation

Galinsky R, Kelly S, Cho S, Zahra V, Menyen M, Hunt R, Nold-Petry C, Gunn A, Polglase G, Hooper S, Nold M.   +10 more
europepmc   +1 more source

IL-1 protects from fatal systemic candidiasis in mice by inhibiting oxidative phosphorylation and hypoxia. [PDF]

Nat Commun
Horn S, Schmid M, Berest I, Piattini F, Zhang J, de Bock K, Devuyst O, Nlandu Khodo S, Kisielow J, Kopf M.   +9 more
europepmc   +1 more source

Pilot Study of IL-1 Antagonist Anakinra for Treatment of Endometriosis. [PDF]

Int J Womens Health
Sullender RT, Agarwal RK, Jacobs MB, Wessels JM, Foster WG, Agarwal SK.   +5 more
europepmc   +1 more source

BET bromodomain inhibitors attenuate transcription of a subset of IL-1-induced NF-κB targets that promote inflammation in β-cells. [PDF]

J Biol Chem
Nord JA, Makowski SJ, Sidlowski PFW, Bursch KL, Corbett JA, Smith BC.   +5 more
europepmc   +1 more source

Taming the flame: WAS and IL-1 blockade.

Blood
Pai SY.
europepmc   +1 more source

Correction: Roles for TAB1 in regulating the IL-1-dependent phosphorylation of the TAB3 regulatory subunit and activity of the TAK1 complex. [PDF]

Biochem J
europepmc   +1 more source