Results 41 to 50 of about 1,850,686 (245)

Evaluación de polimorfismos en los genes de TNF-alfa, TNF-beta e IL-1beta y sus variantes alélicas en una población colombiana de pacientes con sepsis

Iatreia, 2010
La sepsis se define como un síndrome de respuesta sistémica en presencia,  confirmada o sospechada de infección. Se manifiesta  con uno o varios marcadores de enfermedad general, inflamación, anormalidad hemodinámica, disfunción orgánica o falla de ...
Carolina Montoya Ruiz, Maira Alegandra Diosa Toro, Paula Andrea Velilla, Fabián Jaimes Barragán   +3 more
doaj  

Andrographolide relieved pathological pain generated by spared nerve injury model in mice

Pharmaceutical Biology, 2018
Context: Andrographolide (Andro), found in large quantities in Andrographis paniculata Nees (Acanthaceae), is anti-inflammatory, especially in the central nervous system (CNS) glia.
Huang-Chi Wang, Hsin-Sheng Tsay, Hui-Nung Shih, Yi-An Chen, Kai-Ming Chang, Dinesh Chandra Agrawal, Siendong Huang, Yi-Lo Lin, Meng-Jen Lee   +8 more
doaj   +1 more source

Interleukin-1 involved in Apoptosis of Beta-Thalassemia/Hemoglobin E Erythroid Progenitor Cells

Asian Journal of Medical Sciences, 2013
Objective: The major pathophysiological features of β-thalassemia are anemia and ineffective erythropoiesis. Ineffective erythropoiesis has been shown by an intense marrow erythroid hyperplasia and increased apoptosis during basophilic to orthochromatic ...
Umesh Prasad Gupta
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Efficacy and Tolerability of Topotecan/Cyclophosphamide/Dinutuximab in Relapsed and Refractory High‐Risk Neuroblastoma: A Multi‐Institutional Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman, Madeleine King, Rajen Mody, Sara‐Jane Onyeama, Araz Marachelian, Thomas Cash, Sara M. Federico, Meaghan Granger, Ami V. Desai, Suzanne Shusterman, Jennifer H. Foster, Elizabeth Sokol, Chelsee Greer, Keri Streby, Holly J. Meany, Kieuhoa T. Vo, Margaret E. Macy, Rochelle Bagatell   +17 more
wiley   +1 more source

Effects of Hemiscorpius lepturus scorpion venom fractions on cytokine release in male rats [PDF]

مجله علوم پزشکی فیض (پیوسته)
Background and Aim: The secretion and activation of cytokines play a significant role in the pathogenesis of scorpion venom. This study aimed to investigate the effects of Hemiscorpius lepturus scorpion venom fractions on the release of IL-1, IL-6, and ...
Daniel Shaebannia, Mohammad Razi jalali, Ali Shahrirari, Hedieh Jafari, Masoumeh Ahmadi zadeh   +4 more
doaj  

Effect of Epigallocatechin Gallate on the Inflammatory Response in Mice (Mus musculus) Kidneys

Journal of Applied Veterinary Science and Technology
Background: Epigallocatechin gallate is the primary polyphenol constituent of green tea. It has the ability to inhibit the pathological processes caused by oxidants. However, in certain cases, the green tea diet is known to exert pro-oxidant effects.
Gegana Wimaldy Airlangga, Balqis Aina Fajriya, Andreas Bandang Hardian   +2 more
doaj   +1 more source

CYTOKINE GENE POLYMORPHISMS AS PREDICTORS OF CHRONIC PAIN SYNDROME IN ONCOLOGY

Сибирский онкологический журнал, 2017
The literature review on the role of cytokine gene polymorphisms in the development of chronic pain in cancer patients was presented using MedLine, PubMed, NEB elibrary.ru, WileyOnlineLibrary, WebofScience, OxfordUniversityPress and SAGEPremier databases
O. P. Bobrova, N. A. Shnayder, M. M. Petrova, K. S. Zyryanov, D. A. Sychev   +4 more
doaj   +1 more source

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy, Elizabeth L. Seashore, W. Susan Cheng, Shondra Clay, Jessica A. Casas, Jennifer H. Foster   +5 more
wiley   +1 more source

Contribution of Toll-Like Receptors and the NLRP3 Inflammasome in Rheumatoid Arthritis Pathophysiology

ImmunoTargets and Therapy, 2021
Sarah Unterberger, Kevin A Davies, Srinivasa Bhargav Rambhatla, Sandra Sacre Brighton and Sussex Medical School, University of Sussex, Falmer, Brighton, BN1 9PS, UKCorrespondence: Sandra Sacre Tel +441273 872865Email s.sacre@bsms.ac.ukAbstract ...
Unterberger S, Davies KA, Rambhatla SB, Sacre S   +3 more
doaj