Results 21 to 30 of about 1,546,418 (287)
The evolution of IL-4 and IL-13 and their receptor subunits [PDF]
, 2015 Peer ...
Secombes, Christopher J., Wang, Tiehui
core +1 more source
Effect of Agmatine on a mouse model of allergic airway inflammation: A comparative study
Autoimmunity, 2022 Introduction Asthma is a chronic lung disease that injures and constricts the airways. This study evaluates the effects of agmatine on ovalbumin (OVA)-induced allergic inflammation of the airways.
Mohammed K. Еlmahdy +3 more
doaj +1 more source
Expression of the Inhibitory CD200 Receptor Is Associated with Alternative Macrophage Activation [PDF]
, 2010 Classical macrophage activation is inhibited by the CD200 receptor (CD200R). Here, we show that CD200R expression was specifically induced on human in vitro polarized macrophages of the alternatively activated M2a subtype, generated by incubation with IL-
Brouwer, Michael S. M. +8 more
core +1 more source
Journal of Asthma and Allergy, 2021 Li Y Drake,1,2 Kathleen R Bartemes,1,3 Kay A Bachman,1 John B Hagan,1 Hirohito Kita1,4 1Division of Allergic Diseases and Department of Medicine, Mayo Clinic, Rochester, MN, USA; 2Department of Anesthesiology and Perioperative Medicine, Mayo Clinic ...
Drake LY +4 more
doaj
Eosinophil-derived IL-13 promotes emphysema [PDF]
European Respiratory Journal, 2019 The inflammatory responses in chronic airway diseases leading to emphysema are not fully defined. We hypothesised that lung eosinophilia contributes to airspace enlargement in a mouse model and to emphysema in patients with chronic obstructive pulmonary disease (COPD). A transgenic mouse model of chronic type 2 pulmonary inflammation (
Alfred D. Doyle +16 more
openaire +2 more sources
MicroRNA regulation of type 2 innate lymphoid cell homeostasis and function in allergic inflammation. [PDF]
, 2017 MicroRNAs (miRNAs) exert powerful effects on immunity through coordinate regulation of multiple target genes in a wide variety of cells. Type 2 innate lymphoid cells (ILC2s) are tissue sentinel mediators of allergic inflammation.
Ansel, K Mark +7 more
core +2 more sources
Allergology International, 2006 Background: Interleukin (IL)-13 induces goblet cell metaplasia and plays an important role in mucus hypersecretion in asthma. We previously reported that IL-13 induced goblet cell differentiation along with less ciliated cell differentiation in guinea ...
Mitsuko Kondo +6 more
doaj +1 more source
IL-13 Receptor α2 Selectively Inhibits IL-13-Induced Responses in the Murine Lung [PDF]
The Journal of Immunology, 2008 Abstract IL-13 is a critical cytokine at sites of Th2 inflammation. In these locations it mediates its effects via a receptor complex, which contains IL-4Rα and IL-13Rα1. A third, high-affinity IL-13 receptor, IL-13Rα2, also exists. Although it was initially felt to be a decoy receptor, this has not been formally demonstrated and the ...
Tao, Zheng +8 more
openaire +2 more sources
Feasibility Analysis of Interleukin-13 as a Target for a Therapeutic Vaccine [PDF]
, 2019 Background: The development of therapeutic vaccines requires thorough knowledge of potential hazards associated with long-term inactivation of self-proteins.
Foerster, John, Molęda, Aleksandra
core +2 more sources
Computational and Structural Biotechnology Journal, 2023 Several anti-inflammatory cytokines have been proposed as markers for exercise monitoring in humans such as the interleukin 1 receptor agonist (IL-ra), or interleukin 13 (IL-13).
Urszula Plisak +4 more
doaj +1 more source