Results 1 to 10 of about 1,408,658 (292)

Role of the IL-23/IL-17 Pathway in Rheumatic Diseases: An Overview

open access: yesFrontiers in Immunology, 2021
Interleukin-23 (IL-23) is a pro-inflammatory cytokine composed of two subunits, IL-23A (p19) and IL-12/23B (p40), the latter shared with Interleukin-12 (IL-12).
Claudia Schinocca   +6 more
doaj   +1 more source

Increased IL-23R+ Th Cells Population Exhibits Higher SLEDAI-2K Scores in Systemic Lupus Erythematosus Patients

open access: yesFrontiers in Immunology, 2021
The IL-23/IL-17 axis plays causative roles in the development and progression of systemic lupus erythematosus (SLE). However, it remains unclear if the IL-17RA+ and IL-23R+ T helper (Th) cells populations are associated with the serum IL-17 and IL-23 ...
Aziz Farah Izati   +9 more
doaj   +1 more source

Protocol for the safety of brodalumab regarding psychiatric comorbidities in patients with psoriasis

open access: yesEuropean Psychiatry, 2022
Introduction Brodalumab, an anti-IL17RA monoclonal antibody, is a treatment option for plaque psoriasis related to increased risk of suicidal ideation and behavior, including completed suicide.However, in the literature no causal relationship is ...
O. Pikou   +4 more
doaj   +1 more source

Characterization of the IL-17 and CD4+ Th17 Cells in the Clinical Course of Dengue Virus Infections

open access: yesViruses, 2020
The aims of this study were to determine the involvement of interleukin 17 (IL-17) and IL-17-producing cells in dengue pathogenesis. Blood samples from dengue virus (DENV)-infected patients were collected on different days after the onset of symptoms ...
Luis Alberto Sánchez-Vargas   +9 more
doaj   +1 more source

Role of IL-17 family cytokines in the progression of IPF from inflammation to fibrosis

open access: yesMilitary Medical Research, 2022
Idiopathic pulmonary fibrosis (IPF) is a fatal chronic interstitial lung disease with no established treatment and is characterized by progressive scarring of the lung tissue and an irreversible decline in lung function.
Yun-Juan Nie   +3 more
doaj   +1 more source

The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside

open access: yesFrontiers in Immunology, 2020
Interleukin-17 (IL-17) is an essential proinflammatory cytokine, which is mainly secreted by the CD4+ helper T cells (Th17 cells) and subsets of innate lymphoid cells.
Taoming Liu   +7 more
doaj   +1 more source

Interleukin-17 Links Inflammatory Cross-Talks Between Comorbid Psoriasis and Atherosclerosis

open access: yesFrontiers in Immunology, 2022
Psoriasis is a chronic, systemic, immune-mediated inflammatory disorder that is associated with a significantly increased risk of cardiovascular disease (CVD).
Yan Wang   +5 more
doaj   +1 more source

Advances in the study of the association between IL-17 and acne

open access: yesPifu-xingbing zhenliaoxue zazhi, 2023
Acne is a chronic inflammatory disease involving the sebaceous unit of hair follicles, with a complex pathogenesis. Currently, it is believed that the pathogenesis of acne is related to androgen levels, excessive sebum secretion, hyperkeratosis of hair ...
Yixue DUAN   +4 more
doaj   +1 more source

IL-17 and IL-10 as potential biomarkers for diagnosing periodontitis patients: A Review

open access: yesDiyala Journal of Medicine, 2023
Background:Evaluation methods for periodontal disorders are continually being refined to yield more precise, reliable, and time-efficient findings.
Maha Abdulsalam Mohammed ,   +1 more
doaj   +1 more source

GENERATION OF IL-17 IMMUNE RESPONSE IN OBESE PATIENTS WITH ASTHMA

open access: yesНаука и инновации в медицине, 2017
Aim - to investigate the influence of IL-17, IL-10 on the level of asthma control among obese patients. Materials and methods. 79 patients with asthma aged from 18 to 65 years were enrolled in our study and categorized into three groups according to ...
MS S Nurdina, VI I Kupaev, OV V Sazonova
doaj   +1 more source

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