Results 171 to 180 of about 5,540,448 (336)

IL-17 receptor–based signaling and implications for disease

Nature Immunology, 2019
Xiaoxia Li, R. Bechara, Junjie Zhao, M. McGeachy, S. Gaffen   +4 more
semanticscholar   +1 more source

Genomic landscape and preclinical models of angiosarcoma

Molecular Oncology, Volume 19, Issue 4, Page 965-983, April 2025.
Angiosarcomas are a rare and aggressive cancer with a poor prognosis for patients. The genomic landscape of angiosarcoma can be highly complex and heterogenous; however, recent studies have identified some common features especially within anatomic and molecular subgroups.
Annaleigh Benton, Bozhi Liu, Lauren E. Gartenhaus, Jason A. Hanna   +3 more
wiley   +1 more source

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

Molecular Oncology, Volume 19, Issue 5, Page 1386-1403, May 2025.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale, Li Li, J. Kyle Bruner, Melody Chou, Bao Nguyen, Jaesung Seo, Ruiqi Zhu, Mark J. Levis, Christine A. Pratilas, Donald Small   +9 more
wiley   +1 more source

The dual role of IL-17 in periodontitis regulating immunity and bone homeostasis. [PDF]

Front Immunol
Tang Z, Jin L, Yang Y.
europepmc   +1 more source

Severe CD4 T Cell-Mediated Immunopathology in Murine Schistosomiasis Is Dependent on IL-12p40 and Correlates with High Levels of IL-17 [PDF]

, 2005
Laura I. Rutitzky, Jessica R. Lopes da Rosa, Miguel J. Stadecker   +2 more
openalex   +1 more source

Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice Is Mediated via the IL-23/IL-17 Axis1

Journal of Immunology, 2009
L. van der Fits, S. Mourits, J. Voerman, Marius Kant, L. Boon, J. Laman, F. Cornelissen, A. Mus, E. Florencia, E. Prens, E. Lubberts   +10 more
semanticscholar   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

Molecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu, Jinqiu Li, Junqi Ma, Ayshamgul Hasim   +3 more
wiley   +1 more source

IL-17 Inhibitor Secukinumab Achieves Remission in Relapsing Polychondritis: A Case Report. [PDF]

Am J Case Rep
Neycheva S, Kamburova A.
europepmc   +1 more source

Proinflammatory cytokines (IL-17, IL-6, IL-18 and IL-12) and Th cytokines (IFN-γ, IL-4, IL-10 and IL-13) in patients with allergic asthma

, 2001
Chun Kwok Wong, C Y Ho, Fanny W.S. Ko, Christopher H.S. Chan, Alice Ho, David S.C. Hui, C. W. K. Lam   +6 more
openalex   +2 more sources

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

Molecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld, Stefan Kühberger, Ricarda Graf, Christine Beichler, Markus Braun, Nadia Dandachi, Ellen Heitzer, Gerald W. Prager   +7 more
wiley   +1 more source