Results 201 to 210 of about 5,540,448 (336)

Genetic Variants of the IL-23/IL-17 Axis and Its Association With Periodontal Disease: A Systematic Review. [PDF]

Immun Inflamm Dis
Rodríguez-Montaño R, Alarcón-Sánchez MA, Lomelí-Martínez SM, Martínez-Bugarin CH, Heboyan A.   +4 more
europepmc   +1 more source

Stimulation of Airway Mucin Gene Expression by Interleukin (IL)-17 through IL-6 Paracrine/Autocrine Loop

, 2003
Yin Chen, Philip Thai, Yu-Hua Zhao, Ye-Shih Ho, Mary M. DeSouza, Reen Wu   +5 more
openalex   +1 more source

Plasma‐activated media selectively induces apoptotic death via an orchestrated oxidative stress pathway in high‐grade serous ovarian cancer cells

Molecular Oncology, Volume 19, Issue 4, Page 1170-1187, April 2025.
High‐grade serous ovarian cancer (HGSOC) is the most common and aggressive type of ovarian cancer with urgent need for new treatment strategies. This study evaluates plasma‐activated media (PAM) as a novel treatment for HGSOC, showing its ability to selectively induce oxidative stress and apoptosis in HGSOC cell lines, patient ascites cells and primary
Lorena T. Davies, Raja Ganesen, John Toubia, Sung‐Ha Hong, Sushil Kumar KC, Martin K. Oehler, Carmela Ricciardelli, Endre J. Szili, Nirmal Robinson, Melissa R. Pitman   +9 more
wiley   +1 more source

Paradoxical psoriasis with IL-17 inhibitors. [PDF]

Rheumatol Adv Pract
Singla S, Luz D.
europepmc   +1 more source

Loss of SETD2 in wild‐type VHL clear cell renal cell carcinoma sensitizes cells to STF‐62247 and leads to DNA damage, cell cycle arrest, and cell death characteristic of pyroptosis

Molecular Oncology, Volume 19, Issue 4, Page 1244-1264, April 2025.
Vulnerability to the small molecule STF‐62247 is observed in SETD2‐inactivated VHL‐positive clear cell renal cell carcinoma (ccRCC) cells. DNA damage and loss of CDC25A leads to cell cycle arrest in S phase. Cleavage of caspase‐3 (CASP3) and gasdermin E (GSDME) suggests cell death by pyroptosis.
Mathieu Johnson, Sandra Turcotte
wiley   +1 more source

Sodium propionate protects against bronchopulmonary dysplasia by inhibiting IL-17-mediated apoptosis of alveolar epithelial cells. [PDF]

Sci Rep
Xie A, Qian W, Ye D, Deng X, Ma Y, Wang R, Zhou Q, Bao Z, Yu R.   +8 more
europepmc   +1 more source

Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease [PDF]

, 2006
Jens G. Lohr, Birgit Knoechel, Jing Jing Wang, Alejandro V. Villarino, Abul K. Abbas   +4 more
openalex   +1 more source

The CDK12–BRCA1 signaling axis mediates dinaciclib‐associated radiosensitivity through p53‐mediated cellular senescence

Molecular Oncology, Volume 19, Issue 4, Page 1265-1280, April 2025.
Dinaciclib blocks CDK12 activity, leading to downregulation of BRCA1, and probably other proteins involved in homologous recombination, promoting nonhomologous end joining. In this scenario, the presence of ionising radiation triggers a p53‐dependent senescent response that yields increased radiosensitivity. Pan‐cyclin‐dependent‐kinase (CDK) inhibitors
Natalia García Flores, Diego M. Fernández‐Aroca, Cristina Garnés‐García, Andrés Domínguez‐Calvo, Jaime Jiménez‐Suárez, Sebastià Sabater, Pablo Fernández‐Aroca, Ignacio Andrés, Francisco J. Cimas, Guillermo de Cárcer, Borja Belandia, Ignacio Palmero, Pablo Huertas, María José Ruiz‐Hidalgo, Ricardo Sánchez‐Prieto   +14 more
wiley   +1 more source

IL-17 Ligand and Receptor Family Members Are Differentially Expressed by Keratinocyte Subpopulations and Modulate Their Differentiation and Inflammatory Phenotype. [PDF]

Int J Mol Sci
Palazzo E, Lotti R, Quadri M, Pincelli C, Marconi A.   +4 more
europepmc   +1 more source

Resistance to Experimental Autoimmune Encephalomyelitis and Impaired IL-17 Production in Protein Kinase Cθ-Deficient Mice [PDF]

, 2006
Seng‐Lai Tan, Jingyong Zhao, Bi Chen, Xinyi Cynthia Chen, Deena L. Hepburn, Jian Wang, Jonathon D. Sedgwick, Subba R. Chintalacharuvu, Songqing Na   +8 more
openalex   +1 more source