Interleukin‐18, IL‐18 binding protein and IL‐18 receptor expression in asthma: a hypothesis showing IL‐18 promotes epithelial cell differentiation [PDF]
Clinical & Translational Immunology, 2021 Objective In asthma, genome‐wide association studies have shown that interleukin‐18 (IL‐18) receptor 1 gene (IL‐18R1) and sputum IL‐18 are increased during exacerbations. However, the role of the IL‐18 axis in bronchial epithelial function is unclear. To
Davinder Kaur +4 more
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IL-15, IL-18 and IL-21 Along the Stress–Smoking–Periodontal Health Axis: A Cross-Sectional Study in Mexican Adults [PDF]
BiomedicinesFrom a psychoneuroimmunology standpoint, stress and cigarette smoking are plausible modulators of periodontal inflammation through neuroendocrine–immune pathways and cytokine networks. Interleukin-18 (IL-1 family), interleukin-21 (common γ-chain cytokine)
Carmen Celina Alonso-Sánchez +6 more
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mAbs, 2023 Here, we generated bispecific antibody (bsAb) derivatives that mimic the function of interleukin (IL)-18 based on single domain antibodies (sdAbs) specific to IL-18 Rα and IL-18 Rβ.
Britta Lipinski +16 more
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INFLUENCE OF AN INHIBITOR OF JNK ON THE SECRETION OF THE INFLAMMASOME–DEPENDENT PROINFLAMMATORY CYTOKINES [PDF]
Journal of IMAB, 2020 Purpose: In this study, we determine the influence of prolonged exposure on organic air pollutants, on the secretion of inflammasome-dependent cytokines IL-1β and IL-18.
Boncho Grigorov +3 more
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Research progress of NLRP3 inflammasome in the pathogenesis of psoriasis
Pifu-xingbing zhenliaoxue zazhi, 2022 NLRP3 inflammasome activates IL-1β and IL-18. In recent years, a large number of in vitro and in vivo studies showed elevations in expression levels of NLRP3 inflammasome, IL-1β and IL-18 in psoriasis.
Siman SHI +4 more
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Pyroptosis in Osteoblasts: A Novel Hypothesis Underlying the Pathogenesis of Osteoporosis
Frontiers in Endocrinology, 2021 Osteoporosis has become a worldwide disease characterized by a reduction in bone mineral density and the alteration of bone architecture leading to an increased risk of fragility fractures.
Zhengbo Tao +10 more
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Prognostic value of IL18 serum levels in COVID-19 Patients at Beni- Suef University Hospital [PDF]
Egyptian Journal of Medical Research, 2022 A cross-sectional, analytical study conducted over a period of 6 months from April to September 2021 after the approval of REC on 50 patients with confirmed positive of COVID-19 by SARS-CoV-2 nucleic acid RT-PCR recruited from Isolation departments and ...
Nada El-Sagheer +3 more
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Toxics, 2022 Administration of recombinant human IL-18 binding protein (rhIL-18BP), a natural antagonist of IL-18, significantly increased mouse survival after lethal doses of irradiation. To further understand the roles of IL-18BP in radiation mitigation, we studied
Wanchang Cui +6 more
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Process Mining Organization (PMO) Modeling and Healthcare Processes
Knowledge, 2023 Process mining organizatioQn (PMO) is an innovative approach based on artificial intelligence (AI) decision making suitable for designing healthcare processes for human resource (HR) organizations.
Angelo Rosa, Alessandro Massaro
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Interleukin-18 and IL-18BP in inflammatory dermatological diseases
Frontiers in Immunology, 2023 Interleukin (IL)-18, an interferon-γ inducer, belongs to the IL-1 family of pleiotropic pro-inflammatory factors, and IL-18 binding protein (IL-18BP) is a native antagonist of IL-18 in vivo, regulating its activity.
Xiaoyun Wang +8 more
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