Results 21 to 30 of about 15,868,375 (334)

IL-27 regulates IL-18 binding protein in skin resident cells [PDF]

, 2012
IL-18 is an important mediator involved in chronic inflammatory conditions such as cutaneous lupus erythematosus, psoriasis and chronic eczema. An imbalance between IL-18 and its endogenous antagonist IL-18 binding protein (BP) may account for increased ...
Wittmann, M, Miriam Wittmann, Werfel, Thomas, Bachmann, M, Doble, Rosella, Muehl, H, Thomas Werfel, Doble Rosella, Pfeilschifter, Josef (Prof. Dr.), Doble, R, Heiko Mühl, Mühl Heiko, Malte Bachmann, Wittmann Miriam, Pfeilschifter, J, Wittmann, Miriam, Bachmann Malte, Werfel, T, Josef Pfeilschifter, Werfel Thomas, Bachmann, Malte, Mühl, Heiko, Rosella Doble, Pfeilschifter Josef   +23 more
core   +2 more sources

Interleukin-18 and IL-18BP in inflammatory dermatological diseases

Frontiers in Immunology, 2023
Interleukin (IL)-18, an interferon-γ inducer, belongs to the IL-1 family of pleiotropic pro-inflammatory factors, and IL-18 binding protein (IL-18BP) is a native antagonist of IL-18 in vivo, regulating its activity.
Xiaoyun Wang, Xiaoyun Wang, Lian Wang, Xiang Wen, Lu Zhang, Xian Jiang, Xian Jiang, Gu He, Gu He   +8 more
doaj   +1 more source

Structural Basis of IL-1 Family Cytokine Signaling

Frontiers in Immunology, 2019
Interleukin-1 (IL-1) family cytokines are key signaling molecules in both the innate and adaptive immune systems, mediating inflammation in response to a wide range of stimuli.
James K. Fields, James K. Fields, James K. Fields, Sebastian Günther, Eric J. Sundberg, Eric J. Sundberg, Eric J. Sundberg   +6 more
doaj   +1 more source

Prognostic value of IL18 serum levels in COVID-19 Patients at Beni- Suef University Hospital [PDF]

Egyptian Journal of Medical Research, 2022
A cross-sectional, analytical study conducted over a period of 6 months from April to September 2021 after the approval of REC on 50 patients with confirmed positive of COVID-19 by SARS-CoV-2 nucleic acid RT-PCR recruited from Isolation departments and ...
Nada El-Sagheer, Azza Gomaa, Laila Alsharaway, Mervat Abdel-Aziz   +3 more
doaj   +1 more source

Interleukin-18 [PDF]

, 2003
Interleukin-18 (IL-18), a recently described member of the IL-1 cytokine superfamily, is now recognized as an important regulator of innate and acquired immune responses.
McInnes, I.B., Robertson, S.E., Gracie, J.A.   +2 more
core   +1 more source

Expression of interleukin-18 receptor in fibroblast-like synoviocytes [PDF]

, 2001
An excess of the proinflammatory substance IL-18 is present in joints of patients with rheumatoid arthritis (RA), and expression of IL-18 receptor (IL-18R) regulates IL-18 bioactivity in various cell types.
Hoelzer, Dieter (Prof. Dr.), Rehart, Stefan, Kalina, Uwe, Kessler, Uta, Kukoc-Zivojnov, Natasa, Kaltwasser, Joachim Peter (Prof. Dr.), Ottmann, Oliver G., Möller, Burkhard   +7 more
core   +1 more source

Thrombin antithrombin complex and IL-18 serum levels in stroke patients

Neurology International, 2010
The complex picture of inflammation and coagulation alterations comes to life in acute stroke phases. Increasing evidence points to a strong interaction and extensive crosstalk between the inflammation and coagulation systems: the interest towards this ...
Ornella Piazza, Giuliana Scarpati, Simona Cotena, Maria Lonardo, Rosalba Tufano   +4 more
doaj   +1 more source

Different members of the IL-1 family come out in different ways: DAMPs vs cytokines?

Frontiers in Immunology, 2013
Intercellular communications control fundamental biological processes required for the survival of multicellular organisms. Secretory proteins are among the most important messengers in this network of information.
Sonia eCarta, Rosa eLavieri, Anna eRubartelli   +2 more
doaj   +1 more source

Choline uptake and metabolism modulate macrophage IL-1β and IL-18 production

Cell Metabolism, 2019
SUMMARY Choline is a vitamin-like nutrient that is taken up via specific transporters and metabolized by choline kinase which converts it to phosphocholine needed for de novo synthesis of phosphatidylcholine (PC), the main phospholipid of cellular ...
E. Sanchez-Lopez, Zhenyu Zhong, A. Stubelius, Shannon R. Sweeney, L. Booshehri, L. Antonucci, R. Liu-Bryan, A. Lodi, R. Terkeltaub, J. Lacal, A. Murphy, H. Hoffman, S. Tiziani, M. Guma, M. Karin   +14 more
semanticscholar   +1 more source

Bidirectional Action of Cenicriviroc, a CCR2/CCR5 Antagonist, Results in Alleviation of Pain-Related Behaviors and Potentiation of Opioid Analgesia in Rats With Peripheral Neuropathy

Frontiers in Immunology, 2020
Clinical management of neuropathic pain is unsatisfactory, mainly due to its resistance to the effects of available analgesics, including opioids. Converging evidence indicates the functional interactions between chemokine and opioid receptors and their ...
Klaudia Kwiatkowski, Katarzyna Pawlik, Katarzyna Ciapała, Anna Piotrowska, Wioletta Makuch, Joanna Mika   +5 more
doaj   +1 more source