Results 21 to 30 of about 1,536,578 (286)

Dysregulated homeostasis of acetylcholine levels in immune cells of RR-multiple sclerosis patients [PDF]

, 2016
Multiple sclerosis (MS) is characterized by pro-inflammatory cytokine production. Acetylcholine (ACh) contributes to the modulation of central and peripheral inflammation.
Biagioni, Stefano, Costantini, Erica, DI BARI, Maria, Di Nicola, Marta, D’Angelo, Chiara, Galizia, Sabrina, Gasperini, Claudio, Orlando, Viviana, Porfilio, Italo, Reale, Marcella, Ruggieri, Serena, Tata, Ada Maria   +11 more
core   +2 more sources

The proinflammatory cytokine interleukin 18 regulates feeding by acting on the bed nucleus of the stria terminalis [PDF]

, 2016
The proinflammatory cytokine IL-18 has central anorexigenic effects and was proposed to contribute to loss of appetite observed during sickness. Here we tested in the mouse the hypothesis that IL-18 can decrease food intake by acting on neurons of the ...
Alboni, Silvia, Benatti, Cristina, Berton, Fulvia, Conti, Bruno, Francesconi, Walter, Mori, Simone, Moroncini, Gianluca, Nguyen, William, S\ue1nchez Alavez, Manuel, Tascedda, Fabio, Zorrilla, Eric   +10 more
core   +1 more source

Different members of the IL-1 family come out in different ways: DAMPs vs cytokines?

Frontiers in Immunology, 2013
Intercellular communications control fundamental biological processes required for the survival of multicellular organisms. Secretory proteins are among the most important messengers in this network of information.
Sonia eCarta, Rosa eLavieri, Anna eRubartelli   +2 more
doaj   +1 more source

Interleukin-18: A Mediator of Inflammation and Angiogenesis in Rheumatoid Arthritis [PDF]

, 2011
Interleukin-18 (IL-18) is a highly regulated inflammatory cytokine that is elevated in synovial tissues and synovial fluids of patients with rheumatoid arthritis (RA) compared with patients with osteoarthritis (OA) and patients with other arthropathies ...
Alisa E. Koch, Ariel A, Cao R, Michael V. Volin, Morel JC, Siegmund B   +5 more
core   +1 more source

IL-33 and IL-18 in Inflammatory Bowel Disease Etiology and Microbial Interactions

Frontiers in Immunology, 2019
The IL-1 cytokines are a newly expanded family, with each of its 11 members playing an important role in health and disease. Typically acting as pro- or anti-inflammatory mediators of first-line innate immunity, their production is particularly important
Michelle A. Williams, Amy O'Callaghan, Sinéad C. Corr   +2 more
doaj   +1 more source

Genetic basis for variation in plasma IL-18 levels in persons with chronic hepatitis C virus and human immunodeficiency virus-1 infections [PDF]

, 2017
Inflammasomes are multi-protein complexes integrating pathogen-triggered signaling leading to the generation of pro-inflammatory cytokines including interleukin-18 (IL-18).
A Auton, A Iannello, A L Cox, A L French, A Sharma, A Y Kim, AJ Puren, AL Cox, AM Matteini, AY Kim, B Aouizerat, BN Howie, C D Lahiri, C Thio, C Vergara, CA Dinarello, D Gustafson, D L Thomas, D Melzer, D Vlahov, E Golub, E L Murphy, G D Kirk, G Lauer, H Guo, H Jia, J Eron, JZ Liu, K Anastos, K Xia, L Franchi, L Tiret, LH Tobler, LJ Carithers, M Busch, M C Villacres, M G Peters, M He, M Lamkanfi, M Tone, M Young, MA Chattergoon, MA Chattergoon, MG Netea, MH Kuniholm, N Bouzgarrou, N Patterson, NR Roshyara, P Duggal, P Duggal, R Latanich, S H Mehta, S Samarani, S Shrestha, S Wawrocki, SL Normand, SR Thompson, T Strowig, T Zeller, TD Kanneganti, TM Frayling, Y Gu, ZL Niu   +62 more
core   +1 more source

Interleukin-18, Functional IL-18 Receptor and IL-18 Binding Protein Expression in Active and Latent Tuberculosis

Pathogens, 2020
A thorough understanding of the processes modulating the innate and acquired immune response to Mycobacterium tuberculosis (M.tb) infection in the context of gene expression is still a scientific and diagnostic problem.
Sebastian Wawrocki, Grzegorz Kielnierowski, Wieslawa Rudnicka, Michal Seweryn, Magdalena Druszczynska   +4 more
doaj   +1 more source

Autophagy in Microglia and Alzheimer's disease [PDF]

, 2019
Alzheimer’s disease (AD) is the most common neurodegenerative disease, characterized by amyloid-beta plaques, neurofibrillary tangles and neuroinflammation. Autophagy has been associated with several neurodegenerative diseases.
Houtman, Judith
core   +1 more source

Development of anti-murine IL-18 binding protein antibodies to stimulate IL-18 bioactivity. [PDF]

J Immunol
Abstract Interleukin (IL)-18 is an immunoregulatory cytokine that acts as a potent inducer of T helper 1 and cytotoxic responses. IL-18 activity is regulated by its decoy receptor IL-18 binding protein (IL-18BP), which forms a high-affinity complex with IL-18 to block binding of the cognate receptors.
Huard A, Fauteux-Daniel S, Goldstein J, Martin P, Jarlborg M, Andries J, Caruso A, Díaz-Barreiro A, Rodriguez E, Vaillant L, Savvides SN, Gabay C.   +11 more
europepmc   +3 more sources

Effects of adenotonsillectomy on plasma inflammatory biomarkers in obese children with obstructive sleep apnea: A community-based study. [PDF]

, 2015
BackgroundObesity and obstructive sleep apnea syndrome (OSA) are highly prevalent and frequently overlapping conditions in children that lead to systemic inflammation, the latter being implicated in the various end-organ morbidities associated with these
Alonso-Álvarez, ML, Bhattacharjee, R, Duran-Cantolla, J, Gileles-Hillel, A, Gozal, D, Kheirandish-Gozal, L, Peris, E, Terán-Santos, J   +7 more
core   +1 more source