Results 71 to 80 of about 1,564,564 (287)
Tuberculosis (TB) regained its position globally as the leading cause of mortality from a single infectious agent after being surpassed by COVID-19 for 3 years consecutively.
Karan Gupta +5 more
doaj +1 more source
The review presents the characteristics of IL-1F4 (IL-18), its mechanisms of action and value in the development of inflammatory response.
A.Ye. Abaturov +2 more
doaj +1 more source
Interleukin-18 expression increases in response to neurovascular damage following soman-induced status epilepticus in rats [PDF]
BACKGROUND: Status epilepticus (SE) can cause neuronal cell death and impaired behavioral function. Acute exposure to potent acetylcholinesterase inhibitors such as soman (GD) can cause prolonged SE activity, micro-hemorrhage and cell death in the ...
Erik A. Johnson +4 more
core +1 more source
ABSTRACT Purpose Malignant rhabdoid tumor of the kidney (MRTK) is a rare, aggressive tumor seen in young children. The optimal timing of resection for locally advanced tumors is not well‐defined. The purpose of this study is to evaluate modern oncologic outcomes and the impact of surgical timing. Methods A multicenter retrospective review was performed
Hannah N. Rinehardt +76 more
wiley +1 more source
INFLAMMASOME NLRP1 DISTINCTIVE FEATURES IN ATOPIC CONDITIONS
The review article focuses on the NLRP1 inflammasome, which was discovered before the others but has been the least investigated. The emergence of the inflammasome in innate immunity container cells is an early event that precedes the development of any ...
Денис Сергеевич Загрешенко +5 more
doaj
NAIP/NLRC4 inflammasome activation in MRP8+ cells is sufficient to cause systemic inflammatory disease. [PDF]
Inflammasomes are cytosolic multiprotein complexes that initiate protective immunity in response to infection, and can also drive auto-inflammatory diseases, but the cell types and signalling pathways that cause these diseases remain poorly understood ...
Nichols, Randilea D +2 more
core +2 more sources
MYCN Amplification in RB1‐Inactivated Retinoblastoma: Association With High‐Risk Features
ABSTRACT Background MYCN amplification occurs in a subset of retinoblastoma cases, both with and without RB1 inactivation. It has been suggested that retinoblastomas with MYCN amplification represent a distinct entity with more aggressive clinical behavior.
Kyriaki Papaioannou +9 more
wiley +1 more source
ABSTRACT Introduction Patients with ovarian cancer often present with massive ascites, leading to significant protein loss during surgical procedures. Although cell‐free concentrated ascites reinfusion therapy (CART) is used in palliative settings to mitigate protein loss, its application in intraoperative settings remains unexplored.
Yutaka Yoneoka +7 more
wiley +1 more source
Interleukin-18 Mediates Immune Responses to Campylobacter jejuni Infection in Gnotobiotic Mice [PDF]
Background Human Campylobacter jejuni infections are progressively rising worldwide. Information about the molecular mechanisms underlying campylobacteriosis, however, are limited.
Alutis, Marie E. +5 more
core +3 more sources
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa +3 more
wiley +1 more source

