Results 81 to 90 of about 15,868,375 (334)

IL-1β/IL-6/CRP and IL-18/ferritin: Distinct Inflammatory Programs in Infections

PLoS Pathogens, 2016
The host inflammatory response against infections is characterized by the release of pro-inflammatory cytokines and acute-phase proteins, driving both innate and adaptive arms of the immune response.
Jeroen Slaats, J. ten Oever, F. L. van de Veerdonk, M. Netea   +3 more
semanticscholar   +1 more source

A role for IL-18 in protective immunity against Mycobacterium tuberculosis.

, 2009
Tuberculosis remains the most hazardous bacterial infection worldwide. The causative agent, Mycobacterium tuberculosis, is a facultative intracellular pathogen of resting MPhi.
Hagens, Kristine, Bärbel Raupach, Stefan H. E. Kaufmann, Kaufmann, Stefan H. E., Daniel Korbel, Schneider, Bianca E, Schneider, Bianca E., Raupach, Bärbel, Enders, Jana, Jana Enders, Markus Koch, Kaufmann, Stefan HE, Hans-Willi Mittrücker, Bianca E. Schneider, Ulrich E. Schaible, Korbel, Daniel, Schaible, Ulrich E, Mittrücker, Hans-Willi, Schaible, Ulrich E., Koch, Markus, Kristine Hagens   +20 more
core   +1 more source

IL-18 (Interleukin-18) produced by renal tubular epithelial cells promotes renal inflammation and injury during deoxycorticosterone/salt-induced hypertension in mice

, 2021
IL-18 (interleukin-18) is elevated in hypertensive patients, but its contribution to high blood pressure and end-organ damage is unknown. We examined the role of IL-18 in the development of renal inflammation and injury in a mouse model of low-renin ...
Diep, Henry, Brooke Huuskes (9495947), Sharma, Prerna, Guzik, Tomasz, Drummond, Grant R., Yeong H Ling (15393518), Saini, Narbada, Tomasz J Guzik (8414667), Arumugam, Thiruma V., Krishnan, Shalini M., Jordyn Thomas (9494048), Henry Diep (9491633), Vinh, Antony, Thiruma Arumugam (9481307), OConnor, Paul M., Ferens, Dorota M., Eicke Latz (416789), Dorota M Ferens (19187941), Antony Vinh (9491777), Hickey, Michael J., Sobey, Christopher G., Prerna Sharma (287982), Mansell, Ashley, Huuskes, Brooke, Grant Drummond (9477542), Jelinic, Maria, Narbada Saini (9481148), Thomas, Jordyn M., Shalini M Krishnan (15393515), Christopher Sobey (7138634), Kemp-Harper, Barbara K., Maria Jelinic (9480407), Michael J Hickey (11403662), Ashley Mansell (18571180), Ling, Yeong H., Paul M O’Connor (21388781), Latz, Eicke, Barbara K Kemp-Harper (15137629)   +37 more
core   +1 more source

Interleukin-18 cytokine gene polymorphism 137G/C (rs187238) and susceptibility to tuberculosis in north India

Monaldi Archives for Chest Disease
Tuberculosis (TB) regained its position globally as the leading cause of mortality from a single infectious agent after being surpassed by COVID-19 for 3 years consecutively.
Karan Gupta, Vibha Uppal, Pranav Ish, Shubham Singh Chauhan, Sibasish Patro, Neeraj Kumar Gupta   +5 more
doaj   +1 more source

The Participation of Interleukin Family 1 in the Development of the Inflammatory Response in Infectious Process. Part 3. Role of IL-1F4 (IL-18)

Zdorovʹe Rebenka, 2014
The review presents the characteristics of IL-1F4 (IL-18), its mechanisms of action and value in the development of inflammatory response.
A.Ye. Abaturov, A.P. Volosovets, Ye.I. Yulish   +2 more
doaj   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

IL-18 decreases TEER in Caco2 monolayers.

, 2018
The TEER was measured during 24 hours after addition of 10 ng/ml of IL-18, 10 ng/ml IL-1β or 100 ng/ml Tat to the cell monolayers. Note dramatic decrease of the TEER occurring at hour 6 post-exposure by both IL-18 and Tat.
Vikram Mehraj (376026), Ossama Allam (5043434), Devendra Amre (356664), Mohammad-Ali Jenabian (49586), Jean-Pierre Routy (118465), Cecile Tremblay (5043428), Ali Ahmad (4805907), Suzanne Samarani (5043431)   +7 more
core   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

The AIM2 inflammasome is a central regulator of intestinal homeostasis through the IL-18/IL-22/STAT3 pathway

Cellular & Molecular Immunology, 2016
Inflammasomes are important for maintaining intestinal homeostasis, and dysbiosis contributes to the pathology of inflammatory bowel disease (IBD) and increases the risk for colorectal cancer.
R. Ratsimandresy, Mohanalaxmi Indramohan, Andrea Dorfleutner, C. Stehlik   +3 more
semanticscholar   +1 more source