Results 11 to 20 of about 1,375,213 (331)

Profile of tildrakizumab-asmn in the treatment of moderate-to-severe plaque psoriasis: evidence to date [PDF]

Psoriasis: Targets and Therapy, 2018
Kristen M Beck, Isabelle M Sanchez, Eric J Yang, Wilson Liao Department of Dermatology, University of California San Francisco, San Francisco, CA, USA Abstract: Plaque psoriasis is an immune-mediated skin disease that affects roughly 3% of adults in the ...
Beck KM, Sanchez IM, Yang EJ, Liao W
doaj   +2 more sources

IL-23 Dependent and Independent Stages of Experimental Arthritis: No Clinical Effect of Therapeutic IL-23p19 Inhibition in Collagen-induced Arthritis [PDF]

, 2013
IL-23p19 deficient mice have revealed a critical role of IL-23 in the development of experimental autoimmune diseases, such as collagen-induced arthritis (CIA).
Asmawidjaja, P. (Patrick), Cornelissen, F.H.J. (Ferry), Corneth, O.B.J. (Odilia), Kikly, K. (Kristine), Lubberts, E.W. (Erik), Mus, A.M.C. (Adriana)   +5 more
core   +17 more sources

Increased IL-23R+ Th Cells Population Exhibits Higher SLEDAI-2K Scores in Systemic Lupus Erythematosus Patients

Frontiers in Immunology, 2021
The IL-23/IL-17 axis plays causative roles in the development and progression of systemic lupus erythematosus (SLE). However, it remains unclear if the IL-17RA+ and IL-23R+ T helper (Th) cells populations are associated with the serum IL-17 and IL-23 ...
Aziz Farah Izati, Aziz Farah Izati, Nur Diyana Mohd Shukri, Nur Diyana Mohd Shukri, Wan Syamimee Wan Ghazali, Wan Syamimee Wan Ghazali, Che Maraina Che Hussin, Che Maraina Che Hussin, Kah Keng Wong, Kah Keng Wong   +9 more
doaj   +1 more source

Commentary: Guselkumab binding to CD64⁺ IL-23-producing myeloid cells enhances potency for neutralizing IL-23 signaling. [PDF]

Front Immunol
Valdiserra G, Di Salvo C, Fornai M, Antonioli L.   +3 more
europepmc   +3 more sources

Comparative Analysis of Single-Cell Transcriptome Data Reveals a Novel Role of Keratinocyte-Derived IL-23 in Psoriasis

Frontiers in Immunology, 2022
Psoriasis, a common inflammatory skin disease, is critically dependent on the IL-23/IL-17 cytokine axis. Although immune cell-derived IL-23 is generally associated with the disease pathogenesis, there have been reports of IL-23 production in ...
Young Joon Park, Yul Hee Kim, Eun-So Lee, You Chan Kim   +3 more
doaj   +1 more source

No Significant Effects of IL-23 on Initiating and Perpetuating the Axial Spondyloarthritis: The Reasons for the Failure of IL-23 Inhibitors

Frontiers in Immunology, 2022
Axial spondyloarthritis (axSpA) is comprised of ankylosing spondylitis (AS) and non-radiographic axSpA. In recent years, the involvement of the interleukin (IL)-23/IL-17 axis in the pathophysiology of axSpA has been widely proposed.
Hua Zhang, Han-Lei Jiang, Sheng-Ming Dai
doaj   +1 more source

The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside

Frontiers in Immunology, 2020
Interleukin-17 (IL-17) is an essential proinflammatory cytokine, which is mainly secreted by the CD4+ helper T cells (Th17 cells) and subsets of innate lymphoid cells.
Taoming Liu, Sheng Li, Shuni Ying, Shunli Tang, Yuwei Ding, Yali Li, Jianjun Qiao, Hong Fang   +7 more
doaj   +1 more source

ASPECTS OF BIODETERIORATION OF LAPIDEOUS SUBMERGED ARTEFACTS: 3D METHODOLOGIES APPLICATION [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2015
Submerged stone archaeological artefacts are bioeroded by endolithic microbiota (cyanobacteria, algae and fungi) and macroborers (Porifera, Bivalvia and Sipuncula).
S. Ricci, F. Antonelli, C. Sacco Perasso
doaj   +1 more source

Circulating Interleukin-23 Levels in Rheumatoid Arthritis and its Relationship to Disease Activity: a Systematic Review with Meta-Analysis

مجله كليه طب الكندي, 2023
Background: Rheumatoid arthritis (RA) is a chronic and systemic autoimmune disease that is characterized by severe synovial inflammation, cartilage erosion, bone loss, and generalized vasculopathy.
Ahmed Azzam, Shaza Abdul Basset Abdul Basset, Heba Khaled, Neveen Refaey, Ahmed Atta Ahmed Ali, Saad abdelrahim saad shoulah, Mohammed Saleh Al Saifi, Mahmoud s.Meleha   +7 more
doaj   +1 more source

Interleukin (IL)–12 and IL-23 Are Key Cytokines for Immunity against Salmonella in Humans [PDF]

, 2004
Patients with inherited deficiency of the interleukin (IL)–12/IL-23–interferon (IFN)–g axis show increased susceptibility to invasive disease caused by the intramacrophage pathogens salmonellae and mycobacteria. We analyzed data on 154 patients with such
Casanova, Jean-Laurent, Dorman, Susan E, Fieschi, Claire, Holland, Steven M, Kumararatne, Dinakantha S, Lammas, David A, MacLennan, Calman A., MacLennan, Jenny M, Ottenhoff, Tom H. M, Picard, Capucine, Sanal, Ozden   +10 more
core   +1 more source