Results 101 to 110 of about 60,064,270 (228)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Ensuring Good Transferability from Pilot- to Large-Scale Optimized Biotech Bubble Column Designs

Bioengineering
Scaling biotechnology processes such as gas fermentation remains resource- and time-intensive, both experimentally and in modeling. To improve the efficiency of reactor geometry optimization, we evaluated the transferability of findings from pilot-scale (
Carolin Link, Jason Bromley, Michael Martin, Ralf Takors   +3 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Expression of IL-17 and IL-31 in Genital Lichen Sclerosus

reservedBackground Il Lichen sclerosus et atrophicus (LSA) è una malattia dermatologica immuno-mediata che colpisce la cute e le mucose, in particolar modo le aree genitali di femmine e maschi.
CHINELLATO, ALBERTO
core  

Roles of Interleukin‐31 in Allergen‐Driven Cough: Linking Protease‐Activated Receptor‐2 Activation and Vagal Ganglion Sensitization in a Dermatophagoides farinae‐Induced Asthma Model

Brain and Behavior
Background Chronic cough, a distressing symptom of allergic asthma, possibly arises from the abnormal activation of airway‐projecting sensory neurons. Levels of interleukin (IL)‐31, a Th2 cytokine known for its neuronal effects in pruritus, are elevated ...
Takayoshi Miyamoto, Chiharu Ohira, Mao Kaneki, Mariko Komuro, Mana Ichikawa, Ibuki Yasuda, Yoshiichi Takagi, Tomoki Fukuyama   +7 more
doaj   +1 more source

Involvement of Leukotriene B4 Released from Keratinocytes in Itch-associated Response to Intradermal Interleukin-31 in Mice

Acta Dermato-Venereologica, 2017
A recent study suggests that interleukin-31 (IL-31) exerts its effect via indirect mechanisms rather than through direct stimulation of cutaneous nerves.
Tsugunobu Andoh, Ayako Harada, Yasushi Kuraishi   +2 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

The activation of IL-31 signal in keratinocytes.

, 2013
(A) Keratinocytes were treated with IL-31 (0∼10 ng/ml) for 8 h, the mRNA expression of CCL2, IL-8 and IL-1β were examined by real time PCR.
Yuji Shirakata (363805), Koji Sayama (363796), Hidenori Okazaki (432879), Yasushi Hanakawa (363808), Xiuju Dai (363810), Mikiko Tohyama (432880), Masamoto Murakami (185337)   +6 more
core   +1 more source

Scratching the surface: biomarkers and neurobiomarkers for improved allergic contact dermatitis management

Frontiers in Allergy
Allergic contact dermatitis (ACD), also known as allergic eczema, is a common inflammatory skin disorder that affects millions of Americans and imposes significant physical, psychological, and economic burdens.
Akimi Sasaki, Manuel Sargen, Anish R. Maskey, Xiu-Min Li, Xiu-Min Li, Xiu-Min Li   +5 more
doaj   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source