Results 111 to 120 of about 8,409,985 (265)

Ensuring Good Transferability from Pilot- to Large-Scale Optimized Biotech Bubble Column Designs

open access: yesBioengineering
Scaling biotechnology processes such as gas fermentation remains resource- and time-intensive, both experimentally and in modeling. To improve the efficiency of reactor geometry optimization, we evaluated the transferability of findings from pilot-scale (
Carolin Link   +3 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Involvement of Leukotriene B4 Released from Keratinocytes in Itch-associated Response to Intradermal Interleukin-31 in Mice

open access: yesActa Dermato-Venereologica, 2017
A recent study suggests that interleukin-31 (IL-31) exerts its effect via indirect mechanisms rather than through direct stimulation of cutaneous nerves.
Tsugunobu Andoh   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

25-Hydroxyvitamin D, IL-31, and IL-33 in Children with Allergic Disease of the Airways [PDF]

open access: yes, 2014
Low vitamin D is involved in allergic asthma and rhinitis. IL-31 and IL-33 correlate with Th2-associated cytokines in allergic disease. We investigated whether low vitamin D is linked with circulating IL-31 and IL-33 in children with allergic disease of ...
Velia Malizia   +15 more
core   +1 more source

Scratching the surface: biomarkers and neurobiomarkers for improved allergic contact dermatitis management

open access: yesFrontiers in Allergy
Allergic contact dermatitis (ACD), also known as allergic eczema, is a common inflammatory skin disorder that affects millions of Americans and imposes significant physical, psychological, and economic burdens.
Akimi Sasaki   +5 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Expression of IL-17 and IL-31 in Genital Lichen Sclerosus

open access: yes
reservedBackground Il Lichen sclerosus et atrophicus (LSA) è una malattia dermatologica immuno-mediata che colpisce la cute e le mucose, in particolar modo le aree genitali di femmine e maschi.
CHINELLATO, ALBERTO
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

La morte e il diritto: il problema dei trapianti d’organo (Profilo penalistico)

open access: yes, 1994
L’intervento è circoscritto ai casi di espianto d’organi dai defunti, con esclusione delle ipotesi di trapianti tra viventi. Dal punto di vista penalistico si esclude la tutelabilità del cadavere in quanto tale, che viene considerato solo come oggetto ...
ALESSANDRI, ALBERTO
core  

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