Results 21 to 30 of about 1,155,232 (268)
Interleukin-31 new biomarker of infectious skin diseases
Journal of V. N. Karazin Kharkiv National University: Series Medicine, 2021 Introduction. The introduction of antiretroviral therapy has significantly improved the long-term prognosis of AIDS patients, but opportunistic infections can still be life-threatening for this population.
Diana Dorosh
doaj +1 more source
Structures and biological functions of IL-31 and IL-31 receptors [PDF]
Cytokine & Growth Factor Reviews, 2008 Interleukin-31, produced mainly by activated CD4(+) T cells, is a newly discovered member of the gp130/IL-6 cytokine family. Unlike all the other family members, IL-31 does not engage gp130. Its receptor heterodimer consists of a unique gp130-like receptor chain IL-31RA, and the receptor subunit OSMRbeta that is shared with another family member ...
Qing, Zhang +4 more
openaire +2 more sources
Veterinary Evidence, 2022 PICO question In dogs with atopic skin disease, is lokivetmab more effective than oclacitinib in reducing the Canine Atopic Dermatitis Lesion Index score (or some other recognised scoring system)?
Bonnie Yuan Tone Cheung
doaj +1 more source
The IL-31/IL-31 receptor axis: general features and role in tumor microenvironment [PDF]
Journal of Leukocyte Biology, 2017 Abstract IL-31 is a recently identified cytokine with a well-defined role in the pathogenesis of pruritus. IL-31, whose production is induced by IL-4 and IL-33, binds a heterodimeric receptor (R) composed of the exclusive IL-31RA chain and the shared oncostatin M R.
Elisa, Ferretti +2 more
openaire +2 more sources
Pathogenesis of Atopic Dermatitis: Current Paradigm [PDF]
Iranian Journal of Immunology, 2019 Atopic dermatitis (AD) is characterized by skin inflammation, barrier dysfunction and chronic pruritus. In this review, recent advances in the pathogenesis of AD are summarized.
Masutaka Furue +5 more
doaj +1 more source
Dupilumab for cancer-associated refractory pruritus
Journal of Allergy and Clinical Immunology: Global, 2023 Background: Pruritus can be an intolerable symptom in patients with cancer. Type 2 inflammation, and specifically, the cytokines IL-4, IL-13, and IL-31, play major roles in the itching process.
Aviv Talmon, MD +8 more
doaj +1 more source
Consensus on the Clinical Approach to Moderate-to-Severe Atopic Dermatitis in Spain: A Delphi Survey [PDF]
, 2020 Background. The purpose of this study was to gather information on the current assessment and management of patients with moderate-to-severe AD in routine daily practice. Methods.
Armario Hita, José Carlos +9 more
core +3 more sources
Interleukin-31 in serum and cerebrospinal fluid of dogs with syringomyelia
BMC Veterinary Research, 2023 Background Syringomyelia is a spinal cord cavity containing cerebrospinal fluid (CSF)-like fluid. If syringomyelia asymmetrically involves the dorsal horn grey matter of the spinal cord, affected dogs show increased signs of dysesthesia and neuropathic ...
Laura Lemke +6 more
doaj +1 more source
Biomolecules, 2023 Microbiome dysbiosis and cytokine alternations are key features of atopic dermatitis (AD) and psoriasis (PsO), two of the most prevalent and burdensome pruritic skin conditions worldwide.
Laura Bonzano +5 more
doaj +1 more source
IL-31 transgenic mice show reduced allergen-induced lung inflammation. [PDF]
Eur J Immunol, 2021 Abstract Interleukin‐31 (IL‐31) is a Th2 cell–derived cytokine that has been closely linked to pruritic skin inflammation. More recently, enhanced IL‐31 serum levels have also been observed in patients with allergic rhinitis and allergic asthma. Therefore, the main aim of this study was to unravel the contribution
Neuper T +12 more
europepmc +5 more sources