Results 151 to 160 of about 4,627,366 (384)

The Participation of Interleukin Family 1 in the Development of the Inflammatory Response in Infectious Process. 4. Role of IL-1F11 (IL-33)

open access: yesZdorovʹe Rebenka, 2014
The review presents the characteristics of cytokine IL-1F11 (IL-33), its mechanisms of action and value in the development of inflammatory response.
A.Ye. Abaturov   +2 more
doaj   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

IL-33 drives group 2 innate lymphoid cell-mediated protection during Clostridium difficile infection

open access: yesNature Communications, 2019
Clostridium difficile (C. difficile) incidence has tripled over the past 15 years and is attributed to the emergence of hypervirulent strains. While it is clear that C.
Alyse L. Frisbee   +12 more
semanticscholar   +1 more source

Infection Control Practices for Vascular Access Management in Hemodialysis: Results From a Nationwide Survey of Japanese National University Hospitals

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Bloodstream infections due to repeated vascular access (VA) puncture and circuit connections remain major concerns in hemodialysis. Therefore, we examined current practices for glove, disinfectant, and personal protective equipment (PPE) use according to VA type in national university hospitals in Japan.
Aiko Yamada   +6 more
wiley   +1 more source

IL-33 stimulates expression of the GPR84 (EX33) fatty acid receptor gene and of cytokine and chemokine genes in human adipocytes [PDF]

open access: yes, 2018
Expression of GPCR fatty acid sensor/receptor genes in adipocytes is modulated by inflammatory mediators, particularly IL-1β. In this study we examined whether the IL-1 gene superfamily member, IL-33, also regulates expression of the fatty acid receptor ...
Alomar, Suliman Y.   +4 more
core   +2 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Association of IL‐33 in modeling type‐2 airway inflammation and pulmonary emphysema in mice

open access: yesImmunity, Inflammation and Disease
We developed pulmonary emphysema and a type 2 airway inflammation overlap mouse model. The bronchoalveolar lavage (BAL) interleukin 13 (IL‐13), IL‐4, and IL‐5 levels in the overlap model were higher than in the pulmonary emphysema model and lower than in
Chika Miyaoka   +11 more
doaj   +1 more source

The role and mechanism of IL-33 in gout [PDF]

open access: yes, 2016
摘要 研究目的:以MSU诱导的小鼠实验性急性痛风为痛风研究模型,来探讨IL-33在急性痛风中的作用及其机制。 研究方法和结果: 1.重组小鼠IL-33的原核表达以及纯化 GST-IL-33融合蛋白经过原核表达、纯化,去除GST标签等步骤,获得了较高纯度的的mrIL-33。 2.对急性痛风患者血清中IL-33的研究 通过收集临床急性痛风患者41例(男39例,女2例)年龄26~91岁,平均58.3岁和44例年龄、性别与之匹配的健康志愿者的血清标本,检测血清中IL-33的含量。结果显示急性痛风患者血清中IL ...
苏群
core  

IL-33 regulates cytokine production and neutrophil recruitment via the p38 MAPK-activated kinases MK2/3 [PDF]

open access: yes, 2019
IL‐33 is an IL‐1‐related cytokine that can act as an alarmin when released from necrotic cells. Once released, it can target various immune cells including mast cells, innate lymphoid cells and T cells to elicit a Th2‐like immune response.
Adachi   +70 more
core   +2 more sources

Proof-of-concept clinical trial of etokimab shows a key role for IL-33 in atopic dermatitis pathogenesis

open access: yesScience Translational Medicine, 2019
First-in-class clinical trial of IL-33 blockade shows inhibition of neutrophil migration into human skin and modulates atopic dermatitis symptoms. Interrupting inflammation in atopic dermatitis The alarmin cytokine IL-33 is implicated in a variety of ...
Yi-Ling Chen   +10 more
semanticscholar   +1 more source

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