The role of IL-36 and 37 in hepatocellular carcinoma [PDF]
Frontiers in ImmunologyHepatocellular carcinoma (HCC) has garnered considerable attention due to its morbidity and mortality. Although the precise mechanisms underlying HCC tumorigenesis remain to be elucidated, evidence suggests that host immunity plays a pivotal role in its ...
Juan Cao +7 more
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Evaluating Serum Levels of IL-33, IL-36, IL-37 and Gene Expression of IL-37 in Patients with Psoriasis Vulgaris [PDF]
Iranian Journal of Allergy, Asthma and Immunology, 2018 Serum levels of interleukin (IL)-33, IL-36 and IL-37 have been reported to be up-regulated in various T helper (Th)1/Th17 mediated autoimmune/inflammatory diseases.
Mojtaba Sehat +4 more
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The anti-inflammatory cytokine IL-37 improves the NK cell-mediated anti-tumor response [PDF]
OncoImmunologyIL-37 is a member of the IL-1 superfamily exerting anti-inflammatory functions in a number of diseases. Extracellular IL-37 triggers the inhibitory receptor IL-1R8 that is known to regulate different NK cell pathways and functional activities including ...
Nadine Landolina +8 more
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The significant role of IL-15, IL-22, IL-37, and caspase 9 in polycystic ovary syndrome: A case-control study in a sample of Iraqi women [PDF]
Journal of Genetic Engineering and BiotechnologyThe study aims to evaluate the significant role of interleukin 15 (IL-15), IL-22, IL-37, and Caspase 9 gene expression in polycystic ovary syndrome (PCOS), focusing on the underlying mechanisms and potential diagnostic or therapeutic implications ...
Noor A. Mohammed +4 more
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Elevated IL-37 Serum Levels in Patients with Transitional Cell Carcinoma of Bladder [PDF]
Iranian Journal of Immunology, 2021 Background: Interleukin-37 (IL-37) is a recently described cytokine that emerges as a natural inhibitor of inflammatory and immune responses. However, IL-37 has not yet been investigated in bladder cancer, and its biological role is unknown.
Mohammad Reza Haghshenas +5 more
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Pivotal Role of Serum IL-37 In Patients with Chronic HBV and HCV
Al-Mustansiriyah Journal of Science, 2023 Interleukin-37 (IL-37) is an anti-inflammatory cytokine that has an intrinsic role in many diseases through its extracellular and intracellular mechanisms. It was found to be in high concentrations in chronic diseases.
Ellaf Abdulljabbar Al-Jaryan +3 more
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Parsing the IL-37-mediated suppression of inflammasome function
, 2023 Interleukin (IL)-37 is a member of the IL-1 family of cytokines. Although its broad anti-inflammatory properties are well described, the effects of IL-37 on inflammasome function remain poorly understood.
Claudia A Nold-Petry (13595455) +9 more
core +3 more sources
Frontiers in Cardiovascular Medicine, 2021 Atherosclerosis, which is a primary cause of cardiovascular disease (CVD) deaths around the world, is a chronic inflammatory disease that is characterised by the accumulation of lipid plaques in the arterial wall, triggering inflammation that is ...
Ching Chee Law +5 more
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The Role of IL-37 and IL-38 in Colorectal Cancer
Frontiers in Medicine, 2022 Colorectal cancer (CRC) is a major killer. Dysregulation of IL-37 and IL-38, both anti-inflammatory cytokines, is observed in auto-immune diseases.
Jie Dang +8 more
doaj +1 more source
Aberrant Expression of Three New Members of IL-1 Family (IL-36α, IL-37 and IL-38) in Patients with Multiple Sclerosis [PDF]
Journal of Advanced Biomedical Sciences, 2023 Background & Objective: Multiple sclerosis (MS) is a neurodegenerative disease that is characterized by demyelination and neuronal dysfunction. The study of the expression of cytokine genes seems to be an appropriate option for assessing their potential ...
Forouzan Ahmadi Khoei +2 more
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