Results 21 to 30 of about 1,206,376 (271)
IL-37 restrains autoimmune diseases
Oncotarget, 2015 Interleukin-37 (IL-37), a newly discovered member of the IL-1 family, has been identified as a natural inhibitor of immune responses [1]. The human IL-37 gene has been confirmed undergo alternative splicing and exists in five splice variants including IL-37a-e, but a mouse homologue has not been reported [2]. The most glaring is IL-37b that encodes the
Liang, Ye, Zhong, Huang
openaire +2 more sources
Innate immunity but not NLRP3 inflammasome activation correlates with severity of stable COPD [PDF]
, 2013 Background In models of COPD, environmental stressors induce innate immune responses, inflammasome activation and inflammation. However, the interaction between these responses and their role in driving pulmonary inflammation in stable COPD is unknown ...
Adcock, I +16 more
core +1 more source
Memory NK cell features exploitable in anticancer immunotherapy [PDF]
, 2019 Besides their innate ability to rapidly produce effector cytokines and kill virus-infected or transformed cells, natural killer (NK) cells display a strong capability to adapt to environmental modifications and to differentiate into long-lived ...
Battella, Simone +5 more
core +2 more sources
Aberrant Expression of Three New Members of IL-1 Family (IL-36α, IL-37 and IL-38) in Patients with Multiple Sclerosis [PDF]
Journal of Advanced Biomedical Sciences, 2023 Background & Objective: Multiple sclerosis (MS) is a neurodegenerative disease that is characterized by demyelination and neuronal dysfunction. The study of the expression of cytokine genes seems to be an appropriate option for assessing their potential ...
Forouzan Ahmadi Khoei +2 more
doaj
Pro-inflammatory signaling by IL-10 and IL-22: bad habit stirred up by interferons? [PDF]
, 2013 Interleukin (IL)-10 and IL-22 are key members of the IL-10 cytokine family that share characteristic properties such as defined structural features, usage of IL-10R2 as one receptor chain, and activation of signal transducer and activator of ...
Mühl, Heiko
core +2 more sources
IL-37 diminishes proteoglycan loss in human OA cartilage: donor-specific link between IL-37 and MMP-3 [PDF]
Osteoarthritis and Cartilage, 2019 A hallmark of osteoarthritis (OA) is degradation of articular cartilage proteoglycans. In isolated human OA chondrocytes, the anti-inflammatory cytokine Interleukin-37 (IL-37) lowers the expression of the proteolytic MMP and ADAMTS enzymes, which mediate this degradation. Therefore, we investigated if IL-37 protects against proteoglycan loss in freshly
E.W. van Geffen +9 more
openaire +3 more sources
Autoimmunity, 2022 Background Fibroblast-like synoviocytes (FLS) are crucial regulators in the pathogenesis of rheumatoid arthritis (RA). Reportedly, microRNA (miR) participates in regulating the pathogenesis of RA.
Ying Wang, Ge Zhang, Wei Huang
doaj +1 more source
Seasonal Flight Patterns of Hemiptera (Excluding Miridae) in a Southern Illinois Black Walnut Plantation [PDF]
, 2017 The seasonal flight patterns of 99 species and subspecies of Hemiptera collected in window traps in a southern Illinois black walnut plantation are compared with similar data from a North Carolina black walnut plantation.
McPherson, J. E, Weber, B. C
core +3 more sources
Potential role of IL-37 in atherosclerosis
Cytokine, 2019 IL-37 is a member of the IL-1 family, but unlike most other members of this family of cytokines, it has wide-ranging anti-inflammatory properties. Initially shown to bind IL-18 binding protein and prevent IL-18-mediated inflammation, its known role has been expanded to include distinct pathways, both intracellular involving the transcription factor ...
McCurdy S., Liu C., Yap J., Boisvert W.
openaire +3 more sources
Chemosensors, 2023 Water scarcity is a major concern in agriculture worldwide. Fruit trees are severely affected by water deprivation in terms of growth, fruit yield, and quality.
Filippo Vurro +10 more
doaj +1 more source