Results 41 to 50 of about 1,990,850 (192)

A Case of Papuloerythroderma Successfully Treated with Dupilumab

open access: yesCase Reports in Dermatology, 2022
Papuloerythroderma is an erythroderma characterized by the composition of dense paving stone shape papules and intertriginous uninvolved skin on the abdominal wall and is often intractable and accompanied by itching.
Ayaka Mizuno   +4 more
doaj   +1 more source

Targeted delivery of anti-inflammatory therapy to rheumatoid tissue by fusion proteins containing an IL-4-linked synovial targeting peptide [PDF]

open access: yes, 2011
We provide first-time evidence that the synovial endothelium-targeting peptide (SyETP) CKSTHDRLC successfully delivers conjugated IL-4 to human rheumatoid synovium transplanted into SCID mice. SyETP, previously isolated by in vivo phage display and shown
Ahuva Nissim   +10 more
core   +1 more source

Targeting IL-4 for the Treatment of Atopic Dermatitis

open access: yesImmunoTargets and Therapy, 2020
Andrea Chiricozzi,1,2 Martina Maurelli,3 Ketty Peris,1,2 Giampiero Girolomoni3 1Dermatologia, Dipartimento Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario A.
Chiricozzi A   +3 more
doaj  

EFFECTS OF IL-4 UPON THE ACTIVITY OF STAT6 TRANSCRIPTION FACTOR IN PERIPHERAL BLOOD LYMPHOCYTES IN BRONCHIAL ASTHMA

open access: yesМедицинская иммунология, 2014
. The aim of the study is to specify the levels of STAT6, and phospho-STAT6 under the influence of IL-4 in patients with bronchial asthma (BA). The samples from ten healthy controls and thirty-three BA patients with allergic and non-allergic clinical ...
V. N. Mineev   +2 more
doaj   +1 more source

Immunomodulatory Effect of Toll-Like Receptor-3 Ligand Poly I:C on Cortical Spreading Depression [PDF]

open access: yes, 2009
The release of inflammatory mediators following cortical spreading depression (CSD) is suggested to play a role in pathophysiology of CSD-related neurological disorders.
Aghabarari, A.   +8 more
core   +2 more sources

Association of the Expression of IL-4 and IL-13 Genes, IL-4 and IgE Serum Levels with Allergic Asthma

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2007
Immune and inflammatory responses mediated by cytokines, play important roles in the pathophysiology of asthma. These responses are associated with overexpression of Th2 cytokines such as IL-4 and IL-13.
Jalil Tavakkol Afshari   +8 more
doaj  

Serum tumor necrosis factor alpha and interleukin-4 levels in patients with Crimean-Congo Hemorrhagic Fever

open access: yesJournal of Microbiology and Infectious Diseases, 2011
Objectives: Crimean-Congo hemorrhagic fever (CCHF) is a tick borne zoonotic infection. Up till now knowledge about pathogenesis of the disease is limited. Cytokine response is quite important during this infection.
Sami Kınıklı   +7 more
doaj   +1 more source

Association between IL-4 gene polymorphisms, IL-4 serum levels, and ankylosing spondylitis

open access: yesGenetics and Molecular Research, 2016
We aimed to investigate the effect of two common polymorphisms in interleukin-4 (IL-4) on serum IL-4 levels and the development of ankylosing spondylitis (AS) in the Chinese population. A total of 420 inpatients and outpatients diagnosed with AS were enrolled as the case group, and 330 healthy volunteers were selected as the control group.
X L, Liu, J K, Ren, Y L, Su
openaire   +2 more sources

Mechanisms altering airway smooth muscle cell Ca(2+) homeostasis in two asthma models [PDF]

open access: yes, 2008
Background: Asthma is characterized by airway remodeling, altered mucus production and airway smooth muscle cell (ASMC) contraction causing extensive airway narrowing. In particular, alterations of ASMC contractility seem to be of crucial importance. The
Bergner, Albrecht   +6 more
core   +1 more source

Probiotics for the Treatment of Atopic Dermatitis in Adults: A Systematic Review and Meta-Analysis

open access: yesIndian Journal of Dermatology
Atopic dermatitis (AD) is a chronic inflammatory skin condition that affects individuals of all ages. While probiotics have been widely studied as a treatment option in children with AD, evidence regarding their efficacy in adults remains limited.
Chen Yingying   +4 more
doaj   +1 more source

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