Results 11 to 20 of about 1,785,815 (239)

Study of immunological parameters associated with asthma with and without bacterial infection in Thi-Qar Province [PDF]

open access: yesRomanian Journal of Medical Practice
Background. Asthma is a prevalent and persistent respiratory condition that impacts more than 300 million individuals globally, leading to substantial illness and death. Objective.
Huda Kareem ABBAS, Huda Kareem ABBAS
doaj   +1 more source

Anti–IL-5 (mepolizumab) therapy reduces eosinophil activation ex vivo and increases IL-5 and IL-5 receptor levels [PDF]

open access: yesJournal of Allergy and Clinical Immunology, 2008
Anti-IL-5 might be a useful therapeutic agent for eosinophilic disorders, yet its immunologic consequences have not been well characterized.We sought to characterize the hematologic and immunologic effects of anti-IL-5 in human subjects.The effects of 3-month infusions of mepolizumab were assessed in 25 patients with a variety of eosinophilic syndromes.
Miguel L, Stein   +6 more
openaire   +2 more sources

Dietary supplementation with fructooligosaccharides ameliorates allergy development following DEHP exposure in mice

open access: yesFood and Agricultural Immunology, 2021
Fructooligosaccharides (FOS), a prebiotic supplement, can enhance immunological responses, probably through regulation of gastrointestinal microflora. On the other hand, some environmental pollutants have adjuvanticity against allergic reactions/diseases.
Akiko Yasuda   +4 more
doaj   +1 more source

MODES OF INTERACTION BETWEEN SPERMATOZOID ABNORMALITIES AND CYTOKINES IN SEMINAL PLASMA FROM INFERTILE MALES

open access: yesМедицинская иммунология, 2014
. Spearman rank correlation analysis was applied to assess some interrelations between morphological abnormalities of spermatozoids in males with long-term infertility, and cytokine levels in their seminal plasma. Such statistical analysis has revealed a
B. I. Aisikovich   +3 more
doaj   +1 more source

The Role of Eosinophil-Derived Neurotoxin and Vascular Endothelial Growth Factor in the Pathogenesis of Eosinophilic Asthma

open access: yesCells, 2023
Asthma is a chronic complex pulmonary disease characterized by airway inflammation, remodeling, and hyperresponsiveness. Vascular endothelial growth factor (VEGF) and eosinophil-derived neurotoxin (EDN) are two significant mediators involved in the ...
Maciej Tota   +4 more
doaj   +1 more source

Anti-il-5 in pediatric allergic diseases [PDF]

open access: yesPediatric Allergy and Immunology, 2020
AbstractInterleukin (IL)‐5 is a potent mediator of the inflammatory cascade in the allergic response. Its predominant role in atopic reactions makes this cytokine an ideal target for blocking the eosinophilic inflammatory hyper‐responsiveness to allergens.
Laura Tenero   +3 more
openaire   +3 more sources

Bifidobacterium longum and Lactobacillus plantarum alleviate house dust mite allergen-induced allergic rhinitis by regulating IL-4, IL-5, and IL-10 expression

open access: yesFood and Agricultural Immunology, 2019
We examined the effects of Bifidobacterium longum IM55, Lactobacillus plantarum IM76, and their (1:1 and 1:9) mixtures (PMs) on house dust mite allergen extract (HDMA)-induced allergic rhinitis (AR) in mice.
Jeon-Kyung Kim   +4 more
doaj   +1 more source

Inflammatory and Anti-Inflammatory Parameters in PCOS Patients Depending on Body Mass Index: A Case-Control Study

open access: yesBiomedicines, 2023
Background: it has been suggested that chronic low-grade inflammation plays an important role in the pathogenesis of polycystic ovary syndrome (PCOS).
Elena Vasyukova   +8 more
doaj   +1 more source

Serum IL-5, POSTN and IL-33 levels in chronic rhinosinusitis with nasal polyposis correlate with clinical severity

open access: yesBMC Immunology, 2022
Background Chronic rhinosinusitis (CRS) is a group of heterogeneous diseases characterized by epithelial inflammation and tissue eosinophilic infiltration.
Hanna Zielińska-Bliźniewska   +5 more
doaj   +1 more source

Targeting IL-5 in COPD.

open access: yesInternational journal of chronic obstructive pulmonary disease, 2019
Many patients with chronic obstructive pulmonary disease (COPD) continue to experience exacerbations despite receiving standard-of-care treatments. Novel approaches to COPD treatment focus on understanding and targeting molecular mechanisms of airway inflammation, airway obstruction, remodeling and lung destruction.
Narendra,Dharani K., Hanania,Nicola A.
openaire   +5 more sources

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