Results 241 to 250 of about 1,863,297 (279)

Eosinophilic Meningoencephalitis Occurred during Oral Corticosteroid Tapering and after Switching from Anti-IL-5 to Anti-IgE Treatment. [PDF]

Intern Med
Nishii Y, Kinoshita T, Sasaki J, Tsuneyoshi S, Irie K, Tateishi T, Tominaga M, Taniwaki T, Hoshino T, Kawayama T.   +9 more
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Serum Concentration of IL-5 Receptor (IL-5R) and Associations with Disease Severity in Patients with Chronic Spontaneous Urticaria (CSU) and Atopic Dermatitis (AD). [PDF]

Int J Mol Sci
Gomułka K, Tota M, Laska J, Gojny K, Sędek Ł.   +4 more
europepmc   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

IL-5 and its receptor.

Japanese Journal of Clinical Immunology, 1990
openaire   +2 more sources

Retracted: Genetic Analysis Reveals Different Mechanisms of IL-5 Involved in the Development of CAD in a Chinese Han Population. [PDF]

Oxid Med Cell Longev
Longevity OMAC.
europepmc   +1 more source

Revealing the significance of IL-2 and IL-5 in SARS-CoV-2-specific T-cell responses in kidney transplant recipients. [PDF]

Npj Viruses
den Hartog Y, Malahe SRK, Rietdijk WJR, Dieterich M, Gommers L, van Baarle D, Diavatopoulos DA, Messchendorp AL, van der Molen RG, Remmerswaal EBM, Bemelman FJ, Kho MML, GeurtsvanKessel CH, Koopmans MPG, Gansevoort RT, Hilbrands LB, Sanders JS, Reinders MEJ, Baan CC, de Vries RD, RECOVAC Consortium.   +20 more
europepmc   +1 more source

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IL-5 and eosinophilia

Current Opinion in Immunology, 2008
While Interleukin-5 (IL-5) is initially identified by its ability to support the growth and differentiation of activated B cells, overexpression of IL-5 significantly increases eosinophil numbers and antibody levels predominantly from an expanded population of B-1 cells in vivo. Conversely, mice lacking a functional gene for IL-5 or IL-5 receptor alpha
Kiyoshi, Takatsu, Hiroshi, Nakajima
openaire   +2 more sources

New frontiers for IL-5

Journal of Allergy and Clinical Immunology, 1997
Part 1 ; Christopher J. Bagley, Angel F.
Bagley, C., Lopez, A., Vadas, M.
openaire   +3 more sources