Results 241 to 250 of about 17,201,482 (284)

Insight into IL-5 as a Potential Target for the Treatment of Allergic Diseases. [PDF]

Biomedicines
Antosz K, Batko J, Błażejewska M, Gawor A, Sleziak J, Gomułka K.   +5 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Evaluation of the levels of interleukins IL-4, IL-13, IL-5, IL-10 and IL-33 in atopic dermatitis patients with and without dupilumab therapy. [PDF]

Front Immunol
Čelakovská J, Čermáková E, Boudková P, Krejsek J.   +3 more
europepmc   +1 more source

IL-5 Inhibitor Treatment in Drug Reaction With Eosinophilia and Systemic Symptoms.

JAMA Dermatol
Hijaz B, Nambudiri VE, Imadojemu S.
europepmc   +1 more source

Effectiveness of anti-IL-5/5Rα biologics in severe asthma in real-world studies: a systematic review and meta-analysis. [PDF]

ERJ Open Res
Kyriakopoulos C, Papadopoulou E, Potonos D, Exarchos K, Beris E, Aggelopoulou C, Tryfon S, Gogali A, Kostikas K.   +8 more
europepmc   +1 more source

Diagnostic utility of Th2 cytokines (IL-4, IL-5, IL-10, and IL-13) in pulpal blood for assessing pulpitis severity. [PDF]

BMC Oral Health
Li Q.
europepmc   +1 more source

Gαi1/3 signaling mediates IL-5-induced eosinophil activation and type 2 inflammation in eosinophilic chronic rhinosinusitis. [PDF]

Front Immunol
Xie H, Ji J, Liu Z, Lu N, Wei Y, Zhou A, Liu J, Jiao Q.   +7 more
europepmc   +1 more source

Anti-IL-5 Pathway Agents in Eosinophilic-Associated Disorders Across the Lifespan. [PDF]

Drugs
Lombardi C, Comberiati P, Ridolo E, Cottini M, Yacoub MR, Casagrande S, Riccò M, Bottazzoli M, Berti A.   +8 more
europepmc   +1 more source

Anti-IL-5 treatment, but not neutrophil interference, attenuates inflammation in a mixed granulocytic asthma mouse model, elicited by air pollution. [PDF]

Respir Res
De Volder J, Bontinck A, Haelterman V, Boon L, Joos GF, Brusselle GG, Maes T.   +6 more
europepmc   +1 more source