IFN-gamma impairs release of IL-8 by IL-1beta-stimulated A549 lung carcinoma cells [PDF]
, 2008 Background Production of interferon (IFN)-gamma is key to efficient anti-tumor immunity. The present study was set out to investigate effects of IFNgamma on the release of the potent pro-angiogenic mediator IL-8 by human A549 lung carcinoma cells ...
Bernhard Zwissler +15 more
core +1 more source
Expression of IL-8 in Kawasaki disease [PDF]
Clinical and Experimental Immunology, 2000 SUMMARYWe investigated, by Northern blotting, ELISA, and a chemotaxis assay, the expression of IL-8 mRNA, the production of IL-8 protein, and the biological activity of mononuclear cells (MNC), polymorphonuclear neutrophils (PMN) and plasma, respectively, from patients with Kawasaki disease (KD) who received intravenous immunoglobulin (IVIG). IL-8 mRNA
T, Asano, S, Ogawa
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IL-8 confers resistance to EGFR inhibitors by inducing stem cell properties in lung cancer [PDF]
, 2017 Epidermal growth factor receptor (EGFR)-targeted strategy is limited by resistance. We identify the potential genes involved in EGFR TKI (tyrosine kinase inhibitor) resistance and study the therapeutic mechanism in the non-small cell lung cancers ...
楊志新;俞松良;吳尚俊;蔡子修;施金元 +1 more
core +1 more source
Priming by recombinant chicken interleukin-2 induces selective expression of IL-8 and IL-18 mRNA in chicken heterophils during receptor-mediated phagocytosis of opsonized and nonopsonized Salmonella enterica serovar enteritidis [PDF]
, 2003 Heterophils, the principal avian polymorphonuclear leukocytes (PMNs) equivalent to the mammalian neutrophil, function as professional phagocytes against bacterial infections, mediate acute inflammation, and respond to cytokine stimulation to aid in ...
Michael H Kogut +5 more
core +1 more source
The influence of sepsis as a complication after trauma on immune response to injury [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2011 Introduction. Mortality rate in trauma complicated with sepsis is exceeding 50%. Outcome is not determined only by infection or trauma, but also by the intensity of immuno-inflammatory response. Objective.
Šurbatović Maja +4 more
doaj +1 more source
IL-8/IL-8 receptor expression in psoriasis and the response to systemic tacrolimus (FK506) therapy [PDF]
Clinical and Experimental Immunology, 1995 SUMMARYRecently, the keratinocyte IL-8/IL-8 receptor (IL-8R) pathway has been implicated in the pathogenesis of psoriasis, and there is evidence that the potent macrolide immune suppressant tacrolimus (formerly FK506) can inhibit this pathway in vitro.
B H, Lemster +5 more
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Journal of Biomedical Science, 2018 Background Glioblastoma multiforme (GBM) is one of the lethal malignant tumors of the central nervous system. Despite advances made in understanding this complex disease, little has been achieved in improving clinical efficacy towards it. Factors such as
Ira Sharma +3 more
doaj +1 more source
Identification of peripheral inflammatory markers between normal control and Alzheimer's disease
BMC Neurology, 2011 Background Multiple pathogenic factors may contribute to the pathophysiology of Alzheimer's disease (AD). Peripheral blood markers have been used to assess biochemical changes associated with AD and mild cognitive impairment (MCI) and involved in their ...
Jo Sangmee +7 more
doaj +1 more source
Cigarette smoke regulates the expression of TLR4 and IL-8 production by human macrophages [PDF]
, 2009 Background Toll-like receptors (TLRs) are present on monocytes and alveolar macrophages that form the first line of defense against inhaled particles.
Esmaeil Mortaz +23 more
core +1 more source
Respiratory Medicine, 1996 Interleukin-8 (IL-8) is a recently described potent chemotactic factor that may be involved in the pathogenesis of pleural effusions. To understand the actual mechanisms mediating the inflammatory response, changes in cellular components and IL-8 level in pleural fluid of different aetiologies were evaluated.
Ceyhan, B.Bağci +4 more
openaire +3 more sources