Results 61 to 70 of about 1,880,528 (243)

The effect of IL-6 on the trophoblast cell line HTR-8/SVneo [PDF]

Archives of Biological Sciences, 2010
Embryonic development up to the blastocyst stage, implantation into the uterine wall and the development of the functional placenta are steps crucial for the establishment of normal pregnancy. Specific cells of the placenta, the trophoblast cells, invade
Jovanović Milica, Kovačević Tamara, Stefanoska Ivana, Vićovac Ljiljana   +3 more
doaj   +1 more source

Mice That Express Human Interleukin-8 Have Increased Mobilization of Immature Myeloid Cells, Which Exacerbates Inflammation and Accelerates Colon Carcinogenesis [PDF]

, 2011
Background & Aims Interleukin (IL)-8 has an important role in initiating inflammation in humans, attracting immune cells such as neutrophils through their receptors CXCR1 and CXCR2. IL-8 has been proposed to contribute to chronic inflammation and cancer.
Ariyama, Hiroshi, Asfaha, Samuel, Dubeykovskaya, Zinaida A., Dubeykovskiy, Alexander N., Ericksen, Russell, Fox, James G., Friedman, Richard A., Frucht, Harold, Muthupalani, Sureshkumar, Shibata, Wataru, Stokes, Sarah, Tomita, Hiroyuki, Wang, Timothy C., Yang, Xiangdong   +13 more
core   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Serum and Urine Interleukin-6 and Interleukin-8 Levels Do Not Differentiate Acute Pyelonephritis from Lower Urinary Tract Infections in Children

Journal of Inflammation Research, 2020
Maysoun Al Rushood,1 Amal AL-Eisa,1 Rajaa’ AL-Attiyah2 1Department of Pediatrics, Faculty of Medicine, Health Sciences Center, Kuwait University, Kuwait City, Kuwait; 2Department of Microbiology, Faculty of Medicine, Health Sciences Center, Kuwait ...
Al Rushood M, AL-Eisa A, AL-Attiyah R
doaj  

Direct and indirect air particle cytotoxicity in human alveolar epithelial cells [PDF]

, 2014
Air particulate matter has been associated with adverse impact on the respiratory system leading to cytotoxic and proinflammatory effects. The biological mechanisms behind these associations may be initiated by inhaled small size particles, particle ...
Astort, Francisco, Maglione, Guillermo Alberto, Orona, Nadia Soledad, Saldiva, P. H. N., Tasat, Deborah Ruth, Yakisich, Juan Sebastian   +5 more
core   +1 more source

Human Cytomegalovirus Gene UL76 Induces IL-8 Expression through Activation of the DNA Damage Response [PDF]

, 2013
Human cytomegalovirus (HCMV), a β-herpesvirus, has evolved many strategies to subvert both innate and adaptive host immunity in order to ensure its survival and propagation within the host.
Costa, Helena, Nascimento, Rute, Parkhouse, Robert Michael Evans, Sinclair, John   +3 more
core   +2 more sources

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

CpG DNA modulates interleukin 1β-induced interleukin-8 expression in human bronchial epithelial (16HBE14o-) cells [PDF]

, 2006
Background Recognition of repeat unmethylated CpG motifs from bacterial DNA through Toll-like receptor (TLR-9) has been shown to induce interleukin (IL)-8 expression in immune cells. We sought to investigate the role of CpG oligodeoxynucleotides (ODN) on
Wong Hector R, Lierl Kristin M, Hughes Valerie S, Parilla N William, Page Kristen   +4 more
core   +2 more sources

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

FPR1 mediates the tumorigenicity of human cervical cancer cells

Cancer Management and Research, 2018
Guangming Cao, Zhenyu Zhang Department of Obstetrics and Gynecology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China Purpose: The present study aimed to investigate the role of FPR1 and the downstream effectors such as NF-κB ...
Cao G, Zhang Z
doaj