Results 11 to 20 of about 81,920,088 (158)

Iron-Catalyzed Sulfonylmethylation of Imidazo[1,2-α]pyridines with N,N-Dimethylacetamide and Sodium Sulfinates. [PDF]

Molecules
Functionalized imidazo[1,2-α]pyridines are important scaffolds in pharmaceuticals. Herein, we present an efficient 3-sulfonylmethylation protocol for imidazo[1,2-α]pyridines by sodium sulfinates in DMA and H2O (2:1) via an FeCl3-catalyzed ...
Sun S, Ye H, Liu H, Li J, Bi X.
europepmc   +2 more sources

Recent Advances in Visible Light-Induced C-H Functionalization of Imidazo[1,2-a]pyridines. [PDF]

Molecules
The imidazo[1,2-a]pyridine skeleton is widely present in many natural products and pharmaceutical agents. Due to its impressive and significant biological activities, such as analgesic, anti-tumor, antiosteoporosis, and anxiolytic properties, the ...
Gao J, Fu X, Yang K, Liu Z.
europepmc   +2 more sources

One-pot synthesis of tetracyclic fused imidazo[1,2-a]pyridines via a three-component reaction. [PDF]

Beilstein J Org Chem, 2016
A novel three-component reaction has been developed to assemble biologically and pharmaceutically important tetracyclic fused imidazo[1,2-a]pyridines in a one-pot fashion utilizing readily available 2-aminopyridines, isatins and isocyanides.
Yang B, Tao C, Shao T, Gong J, Che C.
europepmc   +2 more sources

C₃-Alkylation of Imidazo[1,2-a]pyridines via Three-Component Aza-Friedel-Crafts Reaction Catalyzed by Y(OTf)₃. [PDF]

Molecules
As an important class of nitrogen-containing fused heterocyclic compounds, imidazo[1,2-a]pyridines often exhibit significant biological activities, such as analgesic, anticancer, antiosteoporosis, anxiolytic, etc.
Yang K, Chen CB, Liu ZW, Li ZL, Zeng Y, Wang ZY.   +5 more
europepmc   +2 more sources

PREPARATION OF NEW NITROGEN-BRIDGED HETEROCYCLES. 63. UNEXPECTED FORMATION OF THIENO[3 ',4 ':4,5]IMIDAZO[1,2-a]-PYRIDINES [PDF]

, 2008
The alkaline treatment and dehydrogenation of pyridinium salts, obtainable from the S-alkylation of 3,5-dimethylpyridinium 2-alkylthio-1-cyano2-thioxoethylides with some phenacyl bromides, afforded unexpected heterocycles, 3-alkylthio-1-arylcarbonyl-6,8 ...
Suga, H, Izumita, A, Kakehi, A, Abe, T   +3 more
core   +3 more sources

Identification of novel Imidazo[1,2-a]pyridine inhibitors targeting M. tuberculosis QcrB [PDF]

, 2012
Mycobacterium tuberculosis is a major human pathogen and the causative agent for the pulmonary disease, tuberculosis (TB). Current treatment programs to combat TB are under threat due to the emergence of multi-drug and extensively-drug resistant TB ...
Fernández, Raquel, Nicholas J Loman, Besra, Gurdyal S., Ballell, L, Raquel Fernández, Pallen, Mark J., Abrahams, Katherine A, Loman, Nicholas J., Abrahams, Katherine A., Spivey, VL, Constantinidou Chrystala, Mark J Pallen, Remuiñán, Modesto J, Cox, Jonathan A G, Abrahams Katherine A., Loman, Nicholas J, Carlos Alemparte, Lluis Ballell, Cox Jonathan A. G., Loman, NJ, Besra, GS, Constantinidou, Chrystala, Alemparte Carlos, Pallen, Mark J, Besra, Gurdyal S; id_orcid, Abrahams, KA, Remuiñán, Modesto J., Besra Gurdyal S., Remuiñán Modesto J., Vickey L Spivey, Chrystala Constantinidou, Pallen, MJ, Barros, D, Loman Nicholas J., Ballell, Lluis, Fernández, R, Alemparte, Carlos, Cox, Jonathan A. G., Cox, JA, Modesto J Remuiñán, Barros David, Jonathan A G Cox, Gurdyal S Besra, Fernández Raquel, Spivey, Vickey L., David Barros, Constantinidou, C, Ballell Lluis, Spivey Vickey L., Barros, David, Spivey, Vickey L, Pallen Mark J., Remuiñán, MJ, Alemparte, C, Katherine A Abrahams   +54 more
core   +1 more source

Regiospecific Synthesis of 3-Substituted Imidazo[1,2-a]pyridines, Imidazo[1,2-a]pyrimidines, and Imidazo[1,2-c]pyrimidine [PDF]

, 2016
3-Substituted imidazo[1,2-a]pyridines, imidazo[1,2-a]pyrimidines, and imidazo[1,2-c]pyrimidine were obtained regiospecifically in yields of 35−92% in one pot by reaction of 2-aminopyridines or 2-(or 4-)aminopyrimidines, respectively, with 1,2-bis ...
Yong-Jiang Xu (1772092), Hongbin Tu (3034200), Alan R. Katritzky (455231)   +2 more
core   +1 more source

Synthesis of new 6-halogeno-imidazo[1,2-a]pyridines by SRN1 reactions [PDF]

, 2003
International audienceNew 2-chloromethyl-6-halogeno-imidazo[1,2-a]pyridines and 2-chloromethyl-6-halogeno-3-nitroimidazo[1,2-a]pyridines were prepared and reacted under experimental conditions of S RN 1 reactions with different sulfur and carbon centered
Maxime D. Crozet, Vanelle, P., Vanelle, Patrice, Mustapha Kaafarani, Crozet, Maxime D., Castera, C., M.P., Crozet, Caroline Castera, Crozet, Michel, P., Patrice Vanelle, Castera, Caroline, M.D., Crozet, Kaafarani, M., Michel P. Crozet, Kaafarani, Mustapha   +14 more
core   +1 more source

Visible-light-mediated C3-azolylation of imidazo[1,2-a]pyridines with 2-bromoazoles [PDF]

, 2017
3-Heterocycle-substituted imidazo[1,2-a]pyridines were produced by a visible-light-mediated coupling reaction of imidazo[1,2-a]pyridines with 2-bromoazoles.
Zhongjie Wu, Peipei Sun, Ping Liu, Lu Yu, Qing Chang   +4 more
core   +1 more source

Nitrosylation of imidazo[1,2-a]pyridines in metal free system [PDF]

, 2017
An efficient nitrosylation of imidazo[1,2-a]pyridines has been developed using tert-Butyl nitrite (TBN) as the NO resource. The nitrosylation protocol demonstrates broad compatibilities, with various functional groups such as halogen, Me, OMe, COOMe et ...
Hao, Xin-Qi, Shen, Xiao-Jing, Zhu, Xinju, Song, Mao-Ping, Wang, Wei, Liang, Zhi-Kun, Liu, Wen-Bo   +6 more
core   +1 more source