Results 11 to 20 of about 81,920,088 (159)

Regiospecific Synthesis of 3-Substituted Imidazo[1,2-a]pyridines, Imidazo[1,2-a]pyrimidines, and Imidazo[1,2-c]pyrimidine

, 2016
3-Substituted imidazo[1,2-a]pyridines, imidazo[1,2-a]pyrimidines, and imidazo[1,2-c]pyrimidine were obtained regiospecifically in yields of 35−92% in one pot by reaction of 2-aminopyridines or 2-(or 4-)aminopyrimidines, respectively, with 1,2-bis ...
Yong-Jiang Xu (1772092), Hongbin Tu (3034200), Alan R. Katritzky (455231)   +2 more
core   +1 more source

Synthesis of new 6-halogeno-imidazo[1,2-a]pyridines by SRN1 reactions

, 2003
International audienceNew 2-chloromethyl-6-halogeno-imidazo[1,2-a]pyridines and 2-chloromethyl-6-halogeno-3-nitroimidazo[1,2-a]pyridines were prepared and reacted under experimental conditions of S RN 1 reactions with different sulfur and carbon centered
Maxime D. Crozet, Vanelle, P., Vanelle, Patrice, Mustapha Kaafarani, Crozet, Maxime D., Castera, C., M.P., Crozet, Caroline Castera, Crozet, Michel, P., Patrice Vanelle, Castera, Caroline, M.D., Crozet, Kaafarani, M., Michel P. Crozet, Kaafarani, Mustapha   +14 more
core   +1 more source

Visible-light-mediated C3-azolylation of imidazo[1,2-a]pyridines with 2-bromoazoles

, 2017
3-Heterocycle-substituted imidazo[1,2-a]pyridines were produced by a visible-light-mediated coupling reaction of imidazo[1,2-a]pyridines with 2-bromoazoles.
Zhongjie Wu, Peipei Sun, Ping Liu, Lu Yu, Qing Chang   +4 more
core   +1 more source

Dimethyl‐, Diethyl‐, and Propylene Carbonates: An Emerging Class of Green Solvents for Organic Synthesis

The Chemical Record, EarlyView.
This review highlights recent advances in the use of organic carbonates, dimethyl carbonate (DMC), diethyl carbonate (DEC), and propylene carbonate (PC), as solvents in organic synthesis. Based on over seventy studies from the past 6 years, it shows their application in different organic reaction types, emphasizing their role in safer and more ...
Gabriela T. Quadros, Livia C. L. Valente, Thiago Barcellos, Daniela Hartwig, Laura Abenante, Eder J. Lenardão   +5 more
wiley   +1 more source

Imidazo(1,2-a)pyridines. III. Synthesis and Bradycardic Activity of New 5-Imidazo(1,2-a)pyridin-6-ylpyridine Derivatives.

Chemical and Pharmaceutical Bulletin, 1992
Structural modification of the cardiotonic agent, loprinone (E-1020, 1), suggested by data that it has a less positive chronotropic effect than milrinone (15), led us to find novel bradycardic agents that were structurally different from homoveratryl amine derivatives. Alkyl-oxy, -thio, and -amino derivatives at the 2-position of the pyridine ring of 1
YAMANAKA, Motosuke, SUDA, Shinji, KABASAWA, Yasuhiro, KAWAMURA, Takanori, OGAWA, Toshiaki, SAWADA, Kouhei, OHHARA, Hideto   +6 more
openaire   +3 more sources

Nitrosylation of imidazo[1,2-a]pyridines in metal free system

, 2017
An efficient nitrosylation of imidazo[1,2-a]pyridines has been developed using tert-Butyl nitrite (TBN) as the NO resource. The nitrosylation protocol demonstrates broad compatibilities, with various functional groups such as halogen, Me, OMe, COOMe et ...
Hao, Xin-Qi, Shen, Xiao-Jing, Zhu, Xinju, Song, Mao-Ping, Wang, Wei, Liang, Zhi-Kun, Liu, Wen-Bo   +6 more
core   +1 more source

Ball-Milling-Enabled Zn(OTf)₂‑Catalyzed Friedel–Crafts Hydroxyalkylation of Imidazo[1,2‑a]pyridines and Indoles

, 2023
A facile and efficient synthetic method for the construction of C3-hydroxyalkylated imidazo[1,2-a]pyridines and indoles by a Zn(OTf)2-catalyzed Friedel–Crafts hydroxyalkylation of imidazo[1,2-a]pyridines and indoles with carbonyl compounds under ...
Sonam (8254197), Krishnan Rangan (2389432), Bhawani (12463900), Anil Kumar (105720), Neha Meena (14615885)   +4 more
core   +2 more sources

Electrophilic Iodination of Heterocyclic Compounds. Recent Advances 2008–2025: Part II

European Journal of Organic Chemistry, Volume 29, Issue 22, 9 June 2026.
Electrophilic iodination using molecular iodine and iodide sources represents an efficient approach for accessing valuable iodinated organic compounds. This review highlights recent advances in the iodination of heterocyclic compounds from 2008 to 2025, emphasizing the role of heteroaryl iodides as important synthetic intermediates for biologically ...
Njomza Ajvazi, Stojan Stavber
wiley   +1 more source

Electrochemical oxidative iodination of imidazo[1,2-a]pyridines using NaI as iodine source

, 2020
An electrochemical oxidative iodination of imidazo[1,2-a]pyridines is achieved in this study. This reaction utilizes NaI as an iodine source and a supporting electrolyte under metal-free and exogenous chemical oxidant-free reaction conditions.
Jin Wha Park (8366643), Dae Young Kim (1734676), Yong Hwan Kim (411929)   +2 more
core   +1 more source

Push–Pull Ynamines and Push–Pull Ynamides: Synthesis, Structure, Reactivity, and Application

European Journal of Organic Chemistry, Volume 29, Issue 19, 22 May 2026.
Push–pull ynamines and push–pull ynamides, which carry an EWG and an amino or amido group as EDG, are highly interesting classes of EDG‐EWG alkynes that have been intensively studied due to their exceptional reactivity. In this review, the synthesis, structure, reactivity, and application of push–pull ynamines, push–pull ynecarbamates, push–pull ...
Hans‐Joachim Gais
wiley   +1 more source