Results 21 to 30 of about 1,977 (163)

Short synthesis and anti-rhinoviral activity of imidazo[1,2-a]pyridines: the effect of acyl groups at 3-position [PDF]

, 1999
Various 2-amino-3-acyl-6-[(E)-1-phenyl-2-N-methylcarbamoylvinyl]-imidazo[1,2-a]pyridines, structurally related to Enviroxime were prepared to determine the effect of acyl groups on the antirhinoviral activity.
Ezquerra, Jesús, Hamdouchi, Chafiq, Heinz, Beverly A., Vaquero López, Juan J., Vega Ramiro, Juan Antonio, Álvarez-Builla Gómez, Julio   +5 more
core   +2 more sources

Push–Pull Ynamines and Push–Pull Ynamides: Synthesis, Structure, Reactivity, and Application

European Journal of Organic Chemistry, EarlyView.
Push–pull ynamines and push–pull ynamides, which carry an EWG and an amino or amido group as EDG, are highly interesting classes of EDG‐EWG alkynes that have been intensively studied due to their exceptional reactivity. In this review, the synthesis, structure, reactivity, and application of push–pull ynamines, push–pull ynecarbamates, push–pull ...
Hans‐Joachim Gais
wiley   +1 more source

Dimethyl‐, Diethyl‐, and Propylene Carbonates: An Emerging Class of Green Solvents for Organic Synthesis

The Chemical Record, EarlyView.
This review highlights recent advances in the use of organic carbonates, dimethyl carbonate (DMC), diethyl carbonate (DEC), and propylene carbonate (PC), as solvents in organic synthesis. Based on over seventy studies from the past 6 years, it shows their application in different organic reaction types, emphasizing their role in safer and more ...
Gabriela T. Quadros, Livia C. L. Valente, Thiago Barcellos, Daniela Hartwig, Laura Abenante, Eder J. Lenardão   +5 more
wiley   +1 more source

The gastric H,K-ATPase in stria vascularis contributes to pH regulation of cochlear endolymph but not to K secretion [PDF]

, 2016
Citation: Miyazaki, H., Wangemann, P., & Marcus, D. C. (2016). The gastric H,K-ATPase in stria vascularis contributes to pH regulation of cochlear endolymph but not to K secretion. BMC Physiology, 17(1), 1.
Marcus, Daniel C., Miyazaki, Hiromitsu, Wangemann, Antje Philine   +2 more
core   +1 more source

Synthesis of Sulfur Heterocycles by Palladium‐Catalyzed Cyclization

European Journal of Organic Chemistry, Volume 29, Issue 14, 15 April 2026.
In spite of the well‐known palladium thiophilicity, sulfur‐containing acyclic substrates may efficiently undergo several different kinds of palladium‐catalyzed cyclization processes leading to highly important sulfur heterocycles in one synthetic step. Advances in this challenging and stimulating field of research are presented in this review.
Bartolo Gabriele
wiley   +1 more source

Substitutive Approach Toward Heteroaromatic Amino Alcohols Accessed Through Dioxolanyl Radical Linchpin

Advanced Synthesis &Catalysis, Volume 368, Issue 7, 1 April 2026.
A dioxolanyl linchpin has been used to synthesize aryl ethanolamines from readily available aryl bromide and amine starting materials using a metallaphotoredox/substitution telescoped sequence. This combinatorial approach allows for a wide synthetic scope of both heteroarenes and cyclic amines. Aryl ethanolamines are an important functional group found
Justin J. Chang, Munnu Kumar, Ryan C. Kashatus, Dylan J. Tomaselli, Daniel K. Kim   +4 more
wiley   +1 more source

Two‐Step Access to 4‐Aryl‐5‐Heteroarylpyrazoles via Palladium‐Catalyzed Sequential Transformations Using Palladium 1,4‐Migration Tool

Asian Journal of Organic Chemistry, Volume 15, Issue 4, April 2026.
Access to pyrazoles arylated at C4 and C5 positions remains challenging due to their similar reactivity under Pd‐catalyzed C–H activation conditions. Herein, we report on the synthesis of 4‐aryl‐5‐heteroarylpyrazoles involving Suzuki‐coupling, followed by Pd‐catalyzed C–H heteroarylation.
Bo Lan, Thierry Roisnel, Henri Doucet
wiley   +1 more source

Hybrid of Indolizine and Merocyanine—A New Class of Organelle‐Specific Dyes

Angewandte Chemie, Volume 137, Issue 47, November 17, 2025.
The new merocyanines and cyanines possessing an indolizine scaffold were synthesized via tandem Friedel–Crafts alkylation followed by nucleophilic aromatic substitution, by leveraging the special reactivity of 2,3,5,6‐tetrafluoro‐4‐hydroxybenzaldehyde.
Jaqueline S. A. Badaro, Beata Koszarna, Maja Perkowska, Kristiana Kandere‐Grzybowska, Diana V. Kolygina, Olaf Morawski, Juhee Park, Bartosz Grzybowski, Irena Deperasińska, Daniel T Gryko   +9 more
wiley   +2 more sources

Copper‐ and Silver‐Catalyzed Reactions of Active Methylene Isocyanides: Facile Access to Highly Substituted Five‐ and Six‐Membered Heterocycles

Chemistry – A European Journal, Volume 32, Issue 13, 1 April 2026.
This review summarizes recent advances in copper‐ and silver‐catalyzed reactions of active methylene isocyanides for the synthesis of highly substituted five‐ and six‐membered heterocycles. Emphasis is placed on [3+n] cycloadditions, annulations, and asymmetric strategies, highlighting current limitations and future opportunities in heterocycle ...
Jimil George, Kyungsoo Oh
wiley   +1 more source

Immobilized Rose Bengal as Photocatalyst for Metal‐Free Thiocyanation of Azaheterocycles under Continuous Flow Conditions [PDF]

, 2023
The immobilization of Rose Bengal onto Merrifield resin and its application in the light-driven metal-free thiocyanation of azaheterocycles in continuo were investigated.
Alessandra Puglisi, Eleonora Colombo, Laura Raimondi, Monica Fiorenza Boselli, Sergio Rossi   +4 more
core   +1 more source