Results 21 to 30 of about 81,920,088 (159)

Imidazo[1,2-b]pyridazines. XII. Syntheses and Central Nervous System Activities of Some Substituted Imidazo[1,2-b]pyridazines and Related Imidazo[1,2-a]pyridines, Imidazo[1,2-a]pyrimidines and Imidazo[1,2-a]pyrazines

, 1992
Syntheses are reported for some 6-chloro(alkoxy,alkylthio and pheny1thio)-3-benzamidomethyl-(acetamidomethyl and methoxy)-2-arylimidazo[1,2-apyridines and some corresponding imidazo- [1,2- b]pyridazines, imidazo[1,2-a[pyrimidines and imidazo[l,2-a ...
SJ Ireland, LP Davies, JK Zhang, GB Barlin, MML Ngu   +4 more
core   +1 more source

Mild and Metal‐Free CH Arylation of Imidazoles via In Situ Diazotization in Water

Advanced Synthesis &Catalysis, Volume 368, Issue 10, 19 May 2026.
Imidazoles undergo direct C–H arylation through in situ generated diazonium salts in water, under ambient and catalyst‐free conditions. This operationally simple method avoids hazardous intermediates, tolerates sensitive functional groups, and preserves C–halogen bonds.
Elisabetta Rosadoni, Zefiro Ferraro Fano, Angela Rosa Cuzzola, Fabio Bellina   +3 more
wiley   +1 more source

In‐situ‐Konstruktion von Imidazopyridinium‐Fluoreszenzlabels für Biokonjugationen

Angewandte Chemie, Volume 138, Issue 21, 18 May 2026.
Durch Chromophor‐Engineering von Isochinolinaldehyden entstehen TICT‐basierte fluorogene Farbstoffe für die In Situ Markierung unterschiedlicher (Bio‐)Moleküle mit großen Stokes‐Verschiebungen, die mit der Zellbildgebung kompatibel sind. ZUSAMMENFASSUNG Einfache, effiziente Transformationen fluorogenen Charakters, die unter biokompatiblen Bedingungen ...
Dongchen Du, László Albert, Milan Weitzel, Linda E. Eijsink, Elena R. Cotroneo, Dennis Marzin, Felipe Opazo, Nadja A. Simeth   +7 more
wiley   +1 more source

In Situ Construction of Imidazopyridinium Fluorescent Labels for Bioconjugation

Angewandte Chemie International Edition, Volume 65, Issue 21, 18 May 2026.
Chromophore engineering of isoquinoline aldehydes generates TICT‐based fluorogenic dyes for in situ labeling of diverse (bio)molecules with large Stokes shifts compatible with cell imaging. ABSTRACT Simple, efficient transformations of fluorogenic nature that proceed under biocompatible conditions without the formation of byproducts are of high ...
Dongchen Du, László Albert, Milan Weitzel, Linda E. Eijsink, Elena R. Cotroneo, Dennis Marzin, Felipe Opazo, Nadja A. Simeth   +7 more
wiley   +1 more source

Group 6 Metal NHC and CAAC Complexes in Homogeneous Catalysis: Reactivity Trends and Selected Applications

ChemCatChem, Volume 18, Issue 9, 14 May 2026.
Group 6 metal complexes of Cr, Mo, and W supported by N‐heterocyclic carbenes are emerging as versatile platforms for homogeneous catalysis. This review highlights advances in reduction, hydrogen transfer, oxidation, and small molecule activation, revealing how ligand design controls reactivity and opens sustainable alternatives to noble‐metal ...
Beatriz Garcia, Alberto Bertoldo, Beatriz Royo   +2 more
wiley   +1 more source

Vanadyl Acetylacetonate Catalyzed Methylenation of Imidazo[1,2-a]pyridines by Using Dimethylacetamide as a Methylene Source: Direct Access to Bis(imidazo[1,2-a]pyridin-3-yl)methanes

, 2016
An efficient protocol has been developed for the methylenation of imidazo[1,2-a]pyridines using dimethylacetamide (DMA) as methylene source in the presence of vanadyl acetylacetonate [VO(acac)2] as the catalyst and iodobenzene diacetate as the oxidant ...
Kaswan, Pinku, DeBoef, Brenton, Kumar, Anil, Nandwana, Nitesh Kumar   +3 more
core   +1 more source

Synthesis of Sulfur Heterocycles by Palladium‐Catalyzed Cyclization

European Journal of Organic Chemistry, Volume 29, Issue 14, 15 April 2026.
In spite of the well‐known palladium thiophilicity, sulfur‐containing acyclic substrates may efficiently undergo several different kinds of palladium‐catalyzed cyclization processes leading to highly important sulfur heterocycles in one synthetic step. Advances in this challenging and stimulating field of research are presented in this review.
Bartolo Gabriele
wiley   +1 more source

Substitutive Approach Toward Heteroaromatic Amino Alcohols Accessed Through Dioxolanyl Radical Linchpin

Advanced Synthesis &Catalysis, Volume 368, Issue 7, 1 April 2026.
A dioxolanyl linchpin has been used to synthesize aryl ethanolamines from readily available aryl bromide and amine starting materials using a metallaphotoredox/substitution telescoped sequence. This combinatorial approach allows for a wide synthetic scope of both heteroarenes and cyclic amines. Aryl ethanolamines are an important functional group found
Justin J. Chang, Munnu Kumar, Ryan C. Kashatus, Dylan J. Tomaselli, Daniel K. Kim   +4 more
wiley   +1 more source

Two‐Step Access to 4‐Aryl‐5‐Heteroarylpyrazoles via Palladium‐Catalyzed Sequential Transformations Using Palladium 1,4‐Migration Tool

Asian Journal of Organic Chemistry, Volume 15, Issue 4, April 2026.
Access to pyrazoles arylated at C4 and C5 positions remains challenging due to their similar reactivity under Pd‐catalyzed C–H activation conditions. Herein, we report on the synthesis of 4‐aryl‐5‐heteroarylpyrazoles involving Suzuki‐coupling, followed by Pd‐catalyzed C–H heteroarylation.
Bo Lan, Thierry Roisnel, Henri Doucet
wiley   +1 more source

Copper‐ and Silver‐Catalyzed Reactions of Active Methylene Isocyanides: Facile Access to Highly Substituted Five‐ and Six‐Membered Heterocycles

Chemistry – A European Journal, Volume 32, Issue 13, 1 April 2026.
This review summarizes recent advances in copper‐ and silver‐catalyzed reactions of active methylene isocyanides for the synthesis of highly substituted five‐ and six‐membered heterocycles. Emphasis is placed on [3+n] cycloadditions, annulations, and asymmetric strategies, highlighting current limitations and future opportunities in heterocycle ...
Jimil George, Kyungsoo Oh
wiley   +1 more source