Results 101 to 110 of about 334,731 (408)

Crystal structure and Hirshfeld surface analysis of a new dithioglycoluril: 1,4-bis(4-methoxyphenyl)-3a-methyltetrahydroimidazo[4,5-d]imidazole-2,5(1H,3H)-dithione

Acta Crystallographica Section E: Crystallographic Communications, 2019
In the title dithioglycoluril derivative, C19H20N4O3S2, there is a difference in the torsion angles between the thioimidazole moiety and the methoxyphenyl groups on either side of the molecule [C—N—Car—Car = 116.9 (2) and −86.1 (3)°, respectively]. The N—
Jonnie N. Asegbeloyin, Kenechukwu J. Ifeanyieze, Obinna C. Okpareke, Ebube E. Oyeka, Tatiana V. Groutso   +4 more
doaj   +1 more source

Quantum probe for molecular synthesis at room temperature [PDF]

arXiv, 2004
In the present study, a prototypical reaction in biochemistry involving a well-known bio-molecule called imidazole (C3H4N2) and its known affinity towards transition metals (such as Co, Ni, Cu, Fe, etc.) has been used to illustrate and exemplify the use of ballistic conductors as probes for molecular reactions at the quantum level.
arxiv  

A Review on Heterocyclic: Synthesis and Their Application in Medicinal Chemistry of Imidazole Moiety

, 2018
In an organic chemistry, largest families of organic compounds are belongs in the heterocyclic compounds. In our daily life important of heterocyclic compounds are of very essential.
Mossaraf Hossain, A. Nanda
semanticscholar   +1 more source

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

Advanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim, Junyeop Kim, Euiyeon Lee, Brandon Conklin, Yannan Hou, Sumin Kim, Yerim Hwang, Ki‐Bum Lee, Jongpil Kim   +8 more
wiley   +1 more source

Etomidate derivatives: Novel pharmaceutical agents in anesthesia

Journal of Anaesthesiology Clinical Pharmacology, 2017
Etomidate is an imidazole derivative that possesses important sedative properties employed in anesthesia practice, however, etomidate has a number of well-know side effects which limit its use in certain subpopulations and over long periods of time ...
Raymond J Malapero, Michael P Zaccagnino, Ethan Y Brovman, Alan David Kaye, Richard D Urman   +4 more
doaj   +1 more source

Kinetics and mechanism of organocatalytic aza-Michael additions: direct observation of enamine intermediates. [PDF]

, 2012
The imidazoles 1a–g add to the CC-double bond of the iminium ion 2 with rate constants as predicted by the equation log k = sN(N + E). Unfavourable proton shifts from the imidazolium unit to the enamine fragment in the adduct 3 account for the failure of
Ahrendt, Albery, Almaşi, Baidya, Brazier, Brotzel, Diner, Dominguez de Maria, Enders, Erkkilä, Grošelj, Herbert Mayr, Komisarska, Lakhdar, Lakhdar, Lelais, List, List, MacMillan, Mahiuddin Baidya, Marcus, Mayr, Mayr, Mayr, Mayr, Mayr, Sami Lakhdar, Schmid, Schmid, Schmid, Seayad, Seebach, Tsogoeva, Uria   +33 more
core   +1 more source

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

Advanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson, Huy Hoang Nguyen, Keng‐Jung Lee, Nattarat Wongsuwan, Ayesha Tupe, Mengrou Lu, Mariah Lynn Arral, Anne Behre, Zihan Ling, Kathryn Ann Whitehead, Adam Walter Feinberg, Xi Ren, Si‐Yang Zheng   +12 more
wiley   +1 more source

Crystal structure of 5-amino-5′-chloro-6-(4-chlorobenzoyl)-8-nitro-2,3-dihydro-1H-spiro[imidazo[1,2-a]pyridine-7,3′-indolin]-2′-one including an unknown solvent molecule

Acta Crystallographica Section E, 2014
The asymmetric unit of the title compound, C21H15Cl2N5O4, contains two independent molecules (A and B) having similar conformations. The amine (NH2) group forms an intramolecular hydrogen bond with the benzoyl group, giving an S(6) ring motif in both ...
R. A. Nagalakshmi, J. Suresh, S. Sivakumar, R. Ranjith Kumar, P. L. Nilantha Lakshman   +4 more
doaj   +1 more source

Halogenation of Imidazolium Ionic Liquids. Thermodynamics Perspective [PDF]

arXiv, 2015
Imidazolium cations are promising for anion exchange membranes, and electrochemical applications and gas capture. They can be chemically modified in many ways including halogenation. Halogenation possibilities of the imidazole ring constitute a particular interest.
arxiv  

Alkali-metal-mediated zincation (AMMZn) meets N-heterocyclic carbene (NHC) chemistry : Zn–H exchange reactions and structural authentication of a dinuclear Au(I) complex with a NHC anion [PDF]

, 2013
Merging two evolving areas in synthesis, namely cooperative bimetallics and N-heterocyclic carbenes (NHCs), this study reports the isolation of the first intermediates of alkali-metal-mediated zincation (AMMZn) of a free NHC and a Zn–NHC complex using ...
Aldeco-Perez, Andrikopoulos, Arduengo, III, Arduengo, III, Armstrong, Armstrong, Armstrong, Armstrong, Arnold, Arnold, Arnold, Back, Baillie, Bantu, Bourissou, Clegg, Clegg, Clegg, Conway, Crabtree, de Frémont, Diez-Gonzalez, Flower, Furuyama, Ghadwal, Gomez-Suarez, Guisado-Barrios, Haag, Hashmi, Hashmi, Hashmi, Hashmi, Hashmi, Hashmi, Jimenez-Nunez, Kobayashi, Kronig, Linton, Masuda, Mendoza-Espinosa, Mulvey, Mulvey, Mulvey, Mulvey, Musgrave, Nobuto, Raubnheimer, Rudolph, Rudolph, Schuster, Uchiyama, Wang, Wang, Wang, Wang, Westerhausen   +55 more
core   +1 more source