Results 21 to 30 of about 339,340 (383)
ChemInform Abstract: DERIVATIVES OF IMIDAZOLE
Chemischer Informationsdienst, 1975 AbstractUnter Anwendung bekannter Wege werden verschiedene in Tabellen aufgeführte Imidazole hergestellt.
S. K. Mahapatra, M. Patra, Byomkesh Dash
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Zur Temperaturabhängigkeit der pH-Abhängigkeit enzymatischer Modellreaktionen
CHIMIA, 1975 The temperature dependence of the pH-dependence of the hydrolysis of p-nitrophenylacetate catalyzed by 4(β-hydroxyethyl)-imidazole, imidazole-propionic acid, cis- and trans-urocanic acid, mercaptoethanole, cysteamine and mercaptomethyl-imidazole was ...
R. von Kleinsorge +2 more
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Frontiers in Chemistry, 2022 An efficient atom-economical synthetic protocol to access new imidazole-based N-phenylbenzamide derivatives is described. A one-pot three-component reaction was utilized to provide a series of N-phenylbenzamide derivatives in a short reaction time (2–4 h)
M. Shaheer Malik +15 more
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Syntheses of polyalkylated imidazoles
Synthetic Communications, 2017 We have developed improved general simple methods for large-scale preparation of polyalkylated imidazoles by improved multicomponent synthesis from commercially available starting materials. A large range of NH- and N-alkyl-polyalkylimidazoles (40 in total, including novel compounds) has been synthesized.
Sigvart Evjen, Anne Fiksdahl
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Solution-phase synthesis of pyrrole-imidazole polyamides [PDF]
, 2009 Pyrrole−imidazole polyamides are DNA-binding molecules that are programmable for a large repertoire of DNA sequences. Typical syntheses of this class of heterocyclic oligomers rely on solid-phase methods. Solid-phase methodologies offer rapid assembly on
Chenoweth, David M. +2 more
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Journal of the American Chemical Society, 2019 Metal-organic frameworks (MOFs) are an emerging class of nanocarriers for drug delivery, owing to their tunable chemical functionality. Here we report ATP-responsive zeolitic imidazole framework-90 (ZIF-90) as a general platform for cytosolic protein ...
Xiaoti Yang +5 more
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Structural Basis for EGFR Mutant Inhibition by Trisubstituted Imidazole Inhibitors.
Journal of Medicinal Chemistry, 2020 Acquired drug resistance in epidermal growth factor receptor (EGFR) mutant non-small cell lung cancer is a persistent challenge in cancer therapy. Previous studies of trisubstituted imidazole inhibitors lead to the serendipitous discovery of inhibitors ...
D. Heppner +4 more
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Molecules, 2013 New imidazole derived thiosemicarbazones and hydrazones were prepared by condensation of 4(5)-imidazole carboxaldehyde, 4-(1H-imidazole-1-yl)benzaldehyde and 4-(1H-imidazole-1-yl)acetophenone with a thiosemicarbazide or hydrazide.
Jacqueline A. Takahashi +7 more
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6-(4-Fluorophenyl)-8-phenyl-2,3-dihydro-4H-imidazo[5,1-b][1,3]thiazin-4-one: an unusual [6-5] fused-ring system [PDF]
, 2007 The title compound, C₁₈H₁₃FN₂OS, is the first structural example of a [6-5] fused ring incorporating the 2,3-dihydro-4H-imidazo[5,1-b][1,3]thiazin-4-one molecular scaffold.
Coleman, Claire M. +3 more
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Dual role of imidazole as activator/inhibitor of sweet almond (Prunus dulcis) β-glucosidase
Biochemistry and Biophysics Reports, 2017 The activity of Prunus dulcis (sweet almond) β-glucosidase at the expense of p-nitrophenyl-β-d-glucopyranoside at pH 6 was determined, both under steady-state and pre-steady-state conditions. Using crude enzyme preparations, competitive inhibition by 1–5
Sara Caramia +4 more
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