Results 21 to 30 of about 303,026 (334)

Zur Temperaturabhängigkeit der pH-Abhängigkeit enzymatischer Modellreaktionen

CHIMIA, 1975
The temperature dependence of the pH-dependence of the hydrolysis of p-nitrophenylacetate catalyzed by 4(β-hydroxyethyl)-imidazole, imidazole-propionic acid, cis- and trans-urocanic acid, mercaptoethanole, cysteamine and mercaptomethyl-imidazole was ...
R. von Kleinsorge, H.G. Löffler, F. Schneider   +2 more
doaj   +1 more source

Thiacalix[4]arene derivatives bearing imidazole units : a ditopic hard/soft receptor for Na⁺ and K⁺/Ag⁺ with an allosteric effect and a reusable extractant for dichromate anions [PDF]

, 2016
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Two novel receptors 5,11,17,23-tetra-tert-butyl-25,27-bis[(ethoxycarbonyl)methoxy]-26,28-bis-[1-methyl-(imidazole)meth-oxy] -2,8,14,20-tetra-thiacalix[4]arene (L1) and 5,11,17,23-tetra-tert-butyl-25,27 ...
Akgemci, Beer, Edwards, Endoh, Goyal, Kovbasyuk, Kremer, Krishna, Kumar, Lamouchi, Li, Liao, Lifschitz, Linton, Livitzki, Melaiye, Molina, Morohashi, Nabeshima, Nabeshima, Nabeshima, Nabeshima, Ni, Ni, Raji, Saiki, Singha, Stryer, Svanholm, Tabakci, Tabakci, Takeuchi, Tomiyasu, Tomiyasu, Yamato, Yamato, Yilmaz, Yilmaz, Zhao, Zhao, Zhao   +40 more
core   +4 more sources

Synthesis and Quantitative Structure–Activity Relationship of Imidazotetrazine Prodrugs with Activity Independent of O6-Methylguanine-DNA-methyltransferase, DNA Mismatch Repair and p53. [PDF]

, 2013
The antitumor prodrug Temozolomide is compromised by its dependence for activity on DNA mismatch repair (MMR) and the repair of the chemosensitive DNA lesion, O6-methylguanine (O6-MeG), by O6-methylguanine-DNA-methyltransferase (EC 2.1.1.63, MGMT). Tumor
Arris C. E., Arrowsmith J., Barvaux V. A., Boberg F., Boyd M. R., Bunz F., Damera K., Darkes M. J. M., De K., Denny B. J., Dimitrios Pletsas, Dinca E. B., Elrashied A. E. Garelnabi, Garelnabi E. A. E., Hirose Y., Honnalli S. S., Judson P. L., Karran P., Karran P., Kotera M., Leteurtre F., Li Li, Liu L., McElhinney R. S., McGarrity J. F., Mladek A. C., Nishizuka S., Pletsas D., Richard T. Wheelhouse, Roger M. Phillips, Sarkaria J. N., Schmidt B. F., Schmiedekamp A., Shealy Y. F., Siddiqui A. A., Smith R. H., Stevens M. F. G., Svilar D., Wang Y., Wheelhouse R. T., Wheelhouse R. T., Zhang J., Zhang J.   +42 more
core   +1 more source

2-[(1H-Imidazol-2-yl)disulfanyl]-1H-imidazole [PDF]

Acta Crystallographica Section E Structure Reports Online, 2011
In the title molecule, C(6)H(6)N(4)S(2), a twofold rotation axis passes through the mid-point of the S-S bond. The C-S-S-C torsion angle is 83.62 (17)°. π-π stacking between imidazole rings of adjacent mol-ecules is observed in the crystal structure, the centroid-centroid distance being 3.447 (2) Å. Inter-molecular N-H⋯S hydrogen bonding results in the
Hamid Reza Khavasi, Soheila Naderi, Laleh Talavat, Mona Feizbakhsh Bazargani   +3 more
openaire   +3 more sources

Catalytically active peptide–gold nanoparticle conjugates: Prospecting for artificial enzymes [PDF]

, 2020
The self‐assembly of peptides onto the surface of gold nanoparticles has emerged as a promising strategy towards the creation of artificial enzymes.
Berger, Allison A., Koksch, Beate, Mikolajczak, Dorian J.   +2 more
core   +1 more source

Two-dimensional protein crystallization via metal-ion coordination by naturally occurring surface histidines [PDF]

, 1996
A powerful and potentially general approach to the targeting and crystallization of proteins on lipid interfaces through coordination of surface histidine residues to lipid-chelated divalent metal ions is presented.
Arnold, Frances H., Chen, Chao-Tsen, Chilkoti, Ashutosh, Frey, Wolfgang, Pack, Daniel W., Schief, William R., Jr., Stayton, Patrick, Vogel, Viola   +7 more
core   +1 more source

Cholinesterase-like organocatalysis by imidazole and imidazole-bearing molecules [PDF]

Scientific Reports, 2017
AbstractOrganocatalysis, which is mostly explored for its new potential industrial applications, also represents a chemical event involved in endogenous processes. In the present study, we provide the first evidence that imidazole and imidazole derivatives have cholinesterase-like properties since they can accelerate the hydrolysis of acetylthiocholine
NIERI, PAOLA, CARPI, SARA, FOGLI, STEFANO, POLINI, BEATRICE, BRESCHI, MARIA CRISTINA, PODESTA', ADRIANO   +5 more
openaire   +3 more sources

Dual role of imidazole as activator/inhibitor of sweet almond (Prunus dulcis) β-glucosidase

Biochemistry and Biophysics Reports, 2017
The activity of Prunus dulcis (sweet almond) β-glucosidase at the expense of p-nitrophenyl-β-d-glucopyranoside at pH 6 was determined, both under steady-state and pre-steady-state conditions. Using crude enzyme preparations, competitive inhibition by 1–5 
Sara Caramia, Angela Gala Morena Gatius, Fabrizio dal Piaz, Denis Gaja, Alejandro Hochkoeppler   +4 more
doaj   +1 more source

(E)-3-[4-(1H-Imidazol-1-yl)phenyl]-1-(3-chloro-4-fluorophenyl)prop-2-en-1-one

Molbank, 2022
Imidazole-containing chalcones have been shown to be effective against Aspergillus fumigatus, the pathogenic agent for pulmonary aspergillosis. Claisen-Schmidt condensation of 4-(1H-imidazol-1-yl)benzaldehyde with 3′-chloro-4′-fluoroacetophenone using ...
Reina Takaki, Bradley O. Ashburn
doaj   +1 more source

Activity In Vitro of Clotrimazole against Canine Methicillin-Resistant and Susceptible Staphylococcus pseudintermedius [PDF]

, 2017
Emergence of multidrug-resistance in Staphylococcus pseudintermedius (SP) has increased interest in topical therapy as an alternative to systemic antibiotics in canine pyoderma.
Bond, R, Frosini, S-M
core   +3 more sources