Results 61 to 70 of about 334,731 (408)
Identification of novel small molecule inhibitors of ETS transcription factors
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla+9 more
wiley +1 more source
Synthesis and Biological Evaluation of Novel Imidazole Derivatives as Antimicrobial Agents
Imidazole derivatives are considered potential chemical compounds that could be therapeutically effective against several harmful pathogenic microbes.
Huda A. Al-Ghamdi+8 more
doaj +1 more source
Second generation silver(I)-mediated imidazole base pairs
The imidazole–Ag(I)–imidazole base pair is one of the best-investigated artificial metal-mediated base pairs. We show here that its stability can be further improved by formally replacing the imidazole moiety by a 2-methylimidazole or 4-methylimidazole ...
Susanne Hensel+3 more
doaj +1 more source
The title compound, C18H28N2S2·CHCl3, crystallizes as a zwitterion. The C—S bonds are almost equivalent, with lengths of 1.666 (3) and 1.657 (3) Å. The S—C—S bond angle is expanded to 129.54 (16)° and the N—C—N angle is reduced to the tetrahedal value of
Eyad Mallah+4 more
doaj +1 more source
Glycerol confined in zeolitic imidazolate frameworks: The temperature-dependent cooperativity length scale of glassy freezing [PDF]
In the present work, we employ broadband dielectric spectroscopy to study the molecular dynamics of the prototypical glass former glycerol confined in two microporous zeolitic imidazolate frameworks (ZIF-8 and ZIF-11) with well-defined pore diameters of 1.16 and 1.46 nm, respectively.
arxiv +1 more source
Activity In Vitro of Clotrimazole against Canine Methicillin-Resistant and Susceptible Staphylococcus pseudintermedius [PDF]
Emergence of multidrug-resistance in Staphylococcus pseudintermedius (SP) has increased interest in topical therapy as an alternative to systemic antibiotics in canine pyoderma.
Bond, R, Frosini, S-M
core +2 more sources
Ultrathin 2D Cobalt Zeolite‐Imidazole Framework Nanosheets for Electrocatalytic Oxygen Evolution
2D layered materials, including metal‐di‐chalcogenides and transition metal layered double hydroxides, among others, are intensively studied because of new properties that emerge from their 2D confinement, which are attractive for advanced applications ...
K. Jayaramulu+10 more
semanticscholar +1 more source
Brucella NyxA and NyxB dimerization enhances effector function during infection
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre+4 more
wiley +1 more source
New route for preparing palmitic acid imidazole from free fatty acid using imidazole
In this study, imidazole was used for the first time in esterification of free fatty acid (FFA) from acidic oil and for palmitic acid imidazole production.
Adeeb Hayyan+12 more
doaj
Biology offers a valuable inspiration toward the development of self-healing engineering composites and polymers. In particular, chemical level design principles extracted from proteinaceous biopolymers, especially the mussel byssus, provide inspiration ...
Stefan Zechel+3 more
doaj +1 more source