Results 181 to 190 of about 92,456 (380)

Trimerization of 1,2‐Diaminocyclohexane Catalyzed by a Metal–Organic Cage Tandem Catalyst with Dual Biomimetic Active Sites

open access: yesAdvanced Science, EarlyView.
Dual biomimetic active sites, i.e., mononuclear {ZnII(L)(H2O)} and dinuclear {L2ZnII(CHO2)(OH)ZnIIL2}, have been successfully intergrated into a metal–organic cage, Zn20‐MOC. These two different active sites in Zn20‐MOC catalyze different steps of cascade trimerization of 1,2‐diaminocyclohexane. The mononuclear {ZnII(L)(H2O)} site catalyzes the initial
Xiao‐Jun Chai   +10 more
wiley   +1 more source

A Unique THN Motif Is Critical for Enabling Efficient C‐Terminal Traceless Cleavage

open access: yesAdvanced Science, EarlyView.
THN is identified as the key motif to facilitate the rapid traceless cleavage of gp41‐1. The deflection of THN motif not only avoids the interaction between C‐exteins and active sites, but also separates Asp107 away from Asn125. In addition, a flexible block F contributes to faster C‐cleavage.
Ruocheng Gu   +7 more
wiley   +1 more source

Structure and Antigenicity of Kaposi's Sarcoma‐Associated Herpesvirus Glycoprotein B

open access: yesAdvanced Science, EarlyView.
Kaposi's sarcoma‐associated herpesvirus (KSHV) causes severe cancers without effective treatments. This study presents an atomic model of KSHV's critical infection protein, gB, revealing a unique structure shared with related herpesviruses like Epstein‐Barr virus (EBV). The structural similarity highlights vulnerable targets for antibodies, guiding the
Xin‐Yan Fang   +8 more
wiley   +1 more source

Design, synthesis, anticancer properties, and molecular docking of imidazolone derivatives with lipophilic moiety. [PDF]

open access: yesSci Rep
Fares O   +10 more
europepmc   +1 more source

Stable Pincer Gold(III)‐TADF Emitters with Extended Donor–Acceptor Separation for Efficient Vacuum‐Deposited OLEDs with Operational Lifetime (LT95) up to 3831 h at 1000 cd m−2

open access: yesAdvanced Science, EarlyView.
Novel pincer gold(III)‐TADF (thermally activated delayed fluorescence) emitters with extended π‐distances exhibit small singlet‐triplet energy gaps (ΔEST), efficient reverse intersystem crossing (RISC), enhanced radiative decay rates and improved excitons utilization, leading to efficient electroluminescence.
Hui‐Xing Shu   +4 more
wiley   +1 more source

Synthesis of Fused sp<sup>3</sup>-Enriched Imidazoles. [PDF]

open access: yesChemistryOpen
Lysenko V   +5 more
europepmc   +1 more source

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