Results 11 to 20 of about 22,275 (301)

Current advances in the synthesis and biological potencies of tri- and tetra-substituted 1H-imidazoles

, 2022
In this report, we review the current chemistry progress and in particular the synthesis approaches of tri- and tetra-substituted imidazoles.
Vahideh Zadsirjan (6272597), Majid Mommahed Heravi (9225485), Mansoureh Daraie (6995462)   +2 more
core   +1 more source

Copper-Catalyzed Direct Cycloaddition of Imidazoles and Alkenes to Trifluoromethylated Tricyclic Imidazoles

, 2021
We reported herein a copper-catalyzed trifluoromethylarylated cycloaddition of imidazoles and olefins using CF3SO2Cl as the radical source to synthesize highly functionalized tricyclic imidazoles.
Yu Chen (29959), Jianchao Cui, Yu Chen, Jianchao Cui (11546450), Yi Li (1144), Yi Li, Shengnan Lin (10760525), Shengnan Lin   +7 more
core   +1 more source

Synthesis of 2,4-Disubstituted Imidazoles via Nucleophilic Catalysis [PDF]

, 2020
A convergent, microwave-assisted protocol for the synthesis of disubstituted NH-imidazoles via nucleophilic catalysis is described. The substituted imidazoles are accessed via the intramolecular addition of a variety of amidoxime substrates to activated ...
Shabalin, Dmitrii A., Dunsford, Jay J., Ngwerume, Simbarashe, Gill, Duncan, Camp, Jason E., Saunders, Alexandra R.   +5 more
core   +1 more source

Fluoroalkylation of Imidazoles by Hypervalent Iodonium Salts

, 2016
N-1H,1H-Perfluoroalkylation and regioselective C-perfluoroalkylation of imidazoles were obtained using the corresponding hypervalent iodonium ...
Darryl D. DesMarteau (2038840), Don VanDerveer (2043787), Changqing Lu (2208802)   +2 more
core   +4 more sources

Polyfunctional Imidazoles: VIII.* 1-Aryl-4-chloro- 5-[R-sulfanyl(R-sulfonyl)methyl]-1H-imidazoles [PDF]

, 2014
Alkylation of (1-aryl-4-chloro-1H-imidazol-5-yl)methanethiols with alkyl halides, propargyl bromide, or chloroacetic acid gave 1-aryl-5-(R-sulfanylmethyl)-4-chloro-1H-imidazoles.
Vovk, M.V., Grozav, A.N., Chornous, V.A., Palamar, A.A.   +3 more
core   +1 more source

Expedient Synthesis of Bis(imidazolium) Dichloride Salts and Bis(NHC) Complexes from Imidazoles using DMSO as a Key Polar Additive [PDF]

, 2021
A general approach for the synthesis of bis(imidazolium) dichloride salts from imidazoles and dichloroalkanes is reported. Typical limitations of this reaction for the formation of methylene-bridged derivatives are addressed herein through the use of an ...
Vincent, Lindsay, Evan, Anders, Kyle, Penn   +2 more
core   +1 more source

An Updated Review on the Synthesis and Antibacterial Activity of Molecular Hybrids and Conjugates Bearing Imidazole Moiety

Molecules, 2020
The rapid growth of serious infections caused by antibiotic resistant bacteria, especially the nosocomial ESKAPE pathogens, has been acknowledged by Governments and scientists and is one of the world’s major health problems.
Renzo Rossi, Maurizio Ciofalo
doaj   +1 more source

The Structure of Biologically Active Functionalized Azoles: NMR Spectroscopy and Quantum Chemistry

Magnetochemistry, 2022
This review summarizes the data on the stereochemical structure of functionalized azoles (pyrazoles, imidazoles, triazoles, thiazoles, and benzazoles) and related compounds obtained by multipulse and multinuclear 1H, 13C, 15N NMR spectroscopy and quantum
Lyudmila I. Larina
doaj   +1 more source

Visible-light-driven Photocatalytic N-arylation of Imidazole Derivatives and Arylboronic Acids on Cu/graphene catalyst

Scientific Reports, 2015
N-aryl imidazoles play an important role as structural and functional units in many natural products and biologically active compounds. Herein, we report a photocatalytic route for the C-N cross-coupling reactions over a Cu/graphene catalyst, which can ...
Yan-Li Cui, Xiao-Ning Guo, Ying-Yong Wang, Xiang-Yun Guo   +3 more
doaj   +1 more source

Versatile Microwave-Assisted and Lanthanum Chloride Catalysed Synthesis of Polysubstituted Imidazoles Using Urea/Thiourea as Benign Source of Ammonia

E-Journal of Chemistry, 2012
Lanthanum chloride was found to be an effective catalyst for the facile and one-pot synthesis of polysubstituted imidazoles under solvent free condition in excellent yields.
Mohammad Reza Manafi, Pedram Manafi, Mohammad Reza Kalaee   +2 more
doaj   +1 more source