Results 191 to 200 of about 95,350 (343)

Chemoselective Cu-catalyzed acylsilylation of vinyl arenes using silylboronates and acyl fluorides. [PDF]

Chem Sci
Zhao Z, Zhou J, Ochiai S, Ikawa S, Shibata N.   +4 more
europepmc   +1 more source

The Versatility of Imidazole and Imidazolium Scaffolds in Sustainable Chemistry and Energy Conversion

Lianghui Li, Shun Tian, Lei Wang, Zhaofu Fei, Paul J. Dyson   +4 more
openalex   +1 more source

The cocrystal of 2,2′-(hydrazine-1,1-diyl)bis(1H-imidazole-4,5-dicarbonitrile)– methanol (2/3) [PDF]

Zhang Yuyao, Bo Wang, Fan Shengping, Yunlu Li   +3 more
openalex   +1 more source

Tuning the reactivity of isocyano group: synthesis of imidazoles and imidazoliums from propargylamines and isonitriles in the presence of multiple catalysts.

Angewandte Chemie, 2015
Shuo Tong, Qian Wang, Mei‐Xiang Wang, Jieping Zhu   +3 more
semanticscholar   +1 more source

Structure‐Guided Engineering of a Cas12i Nuclease Unlocks Near‐PAMless Genome Editing

Advanced Science, EarlyView.
CRISPR‐Cas nucleases are limited by PAM requirements, restricting genome accessibility. Structure‐guided engineering of the compact Cas12i nuclease SF01 produced three variants with near‐PAMless, enabling efficient editing at diverse 5'‐NNTN‐3' sites. These nucleases expand the editable portion of the human genome more than fourfold, enabling efficient
Qitong Chen, Hanlin Gou, Chao Xu, Sihan Wang, Huitao Zhang, Minglei Song, Mengge Wang, Xingkun Ji, Xiaofei Wei, Yuanyan Tan, Hehua Quan, Pengyu Luo, Hanyu Shou, Pengpeng Liu, Yafeng Liang, Jian‐Kang Zhu   +15 more
wiley   +1 more source

Synthesis of Fused sp³-Enriched Imidazoles. [PDF]

ChemistryOpen
Lysenko V, Portiankin A, Shvydenko T, Shishkina S, Nazarenko K, Kostyuk A.   +5 more
europepmc   +1 more source

Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1

Advanced Science, EarlyView.
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang, Yi Liu, Zhiying Yao, Haolong Lai, Xiaoxin Chen, Ziqiu Wang, Yiqiong Bao, Tingting Li, Xiaoming Zhou, Xiabin Chen, Peiguo Yang   +10 more
wiley   +1 more source

New Anticancer Agents: Design, Synthesis and Evaluation. [PDF]

Int J Mol Sci
Pokrovsky V, Addeo R, Coluccia M.
europepmc   +1 more source

SMart Nanoparticle–Hydrogel Hybrid System for Synergistic Eradication of Infection and Promotion of Wound Healing

Advanced Science, EarlyView.
The integrated system, comprising bacterial‐targeted photothermal nanoparticles (Fe2O3‐CS@RBP) and multifunctional hydrogels (PAOC‐3@BA) modules, achieves rapid wound healing within one week. This work introduces a smart therapeutic platform that integrates bacterial targeting, self‐regulating photothermal therapy, tissue adhesion, and stimulus ...
Hongping Wan, Huirong Tan, Xinghong Zhao
wiley   +1 more source

Greening of Monocyclic N- and O‑Azole Synthesis through Sonochemistry. [PDF]

ACS Omega
Hoffman GR, Saeed MM, Schoffstall AM.
europepmc   +1 more source