Kinetics and Mechanism of the Reactions of Butenenitrile with Imidazoles [PDF]
, 1976 Fukiko Yamada +3 more
openalex +1 more source
STING COPII ER Export Trafficking and Signaling Primed by Phosphorylation Switches
Advanced Science, EarlyView.This schematic outlines STING trafficking and signaling via coat protein II (COPII)‐mediated endoplasmic reticulum (ER) export. Following cyclic GMP‐AMP (cGAMP) stimulation, TANK‐binding kinase 1 (TBK1) activates on COPII vesicles, partially dissociating into the cytosol to phosphorylate ER‐localized STING, creating pSGME/pFS COPII‐sorting motifs ...
Yanan Nan +10 more
wiley +1 more source
Imidazole Catalyses in Aqueous Systems. X. Enzyme-like Catalytic Hydrolyses of Phenyl Esters by Polymers Containing Imidazole and Other Anionic Functions [PDF]
, 1975 Seiji Shinkai, Toyoki Kunitake
openalex +1 more source
DERIVADOS METÁLICOS DE IMIDAZOLES CON Cu(II), Zn(II) Y Ag(I) Y SU POTENCIAL USO COMO AGENTES ANTIMICÓTICOS CONTRA CANDIDA ALBICANS [PDF]
, 2014 Estrada Garcia, Fernando +1 more
core
USP8‐Governed MDA5 Homeostasis Promotes Innate Immunity and Autoimmunity
Advanced Science, EarlyView.This study reveals that USP8 stabilizes MDA5 via AKT‐mediated phosphorylation (Ser718), enhancing their interaction and MDA5 deubiquitination. USP8 inactivation degrades MDA5, suppressing type I IFN and cytokine production. Pharmacological inhibition of USP8/AKT alleviates MDA5‐driven autoimmunity, demonstrating the USP8‐MDA5 axis as a therapeutic ...
Qimin Zhang +9 more
wiley +1 more source
Imidazoles and Quaternary Ammonium Compounds as Effective Therapies against (Multidrug-Resistant) Bacterial Wound Infections. [PDF]
Antibiotics (Basel)Van de Vliet L +4 more
europepmc +1 more source
Antifungal Activity of Tioconazole (UK-20,349), a New Imidazole Derivative
, 1979 S. Jevons +4 more
openalex +1 more source
Advanced Science, EarlyView.Akkermansia depletion correlates with acute pancreatitis (AP) severity. A. muciniphila and its protein Amuc_1409 mitigate pancreatic/systemic inflammation by expanding Tregs and IL‐10. Mechanistically, Amuc_1409 binds Ube2k, inhibiting Foxp3 ubiquitination to stabilize Treg differentiation and IL‐10 production, countering SAP‐induced SIRS/CARS ...
Jinyan Xie +9 more
wiley +1 more source
Solvent-free approach for the synthesis of heterometallic Fe-Zn-ZIF glass <i>via</i> a melt-quenched process. [PDF]
Chem SciLeón-Alcaide L +6 more
europepmc +1 more source