Results 271 to 280 of about 52,674 (356)

Mortalin and PINK1/Parkin‐Mediated Mitophagy Represent Ovarian Cancer‐Selective Targets for Drug Development

open access: yesAdvanced Science, EarlyView.
Ovarian cancer patients with high levels of mortalin protein in their tumors have worse survival. The investigational drug SHetA2 interferes with mortalin's support of mitochondria. The resulting mitochondrial damage causes a process called mitophagy that contributes to how SHetA2 kills cancer cells. Noncancerous cells repair their mitochondria through
Vishal Chandra   +9 more
wiley   +1 more source

Confinement‐Induced Metastable Supramolecular Assembly: Dynamic Built‐in Electric Field Driving Deep Mineralization of Organic Pollutants

open access: yesAdvanced Science, EarlyView.
Utilizing the 2D confined space of layered double hydroxide (LDH), living supramolecular assembly (LSA) are successfully prepared with smaller intermolecular distances than in crystals. The IEF enhancement value can reach 11.8 times, which induces a charge separation efficiency of 71.52%.
Xiaoqing Cao   +4 more
wiley   +1 more source

Recent in vitro advances in the ocular antimicrobial agents against Acanthamoeba. [PDF]

open access: yesInt J Parasitol Drugs Drug Resist
Chen CH   +4 more
europepmc   +1 more source

Zwitterion‐Stabilized Superlattices and Frank‐Kasper Phases in Charged Block Copolymers for Mechanically Robust Dielectric Soft Materials

open access: yesAdvanced Science, EarlyView.
Superlattices formed by the co‐assembly of acid‐functionalized block copolymers and zwitterions exhibit tunable morphologies, transitioning from lamellae to cylinders to Frank‐Kasper phases. Zwitterion interfacial localization enhances dielectric constant, mechanical strength, and thermal stability, making these materials promising for soft electronics
Jaemin Min, Hojun Lee, Moon Jeong Park
wiley   +1 more source

CO2‐DBU‐Triggered Photoredox‐Catalyzed Direct α‐C‐H Alkylation of Alcohols

open access: yesAdvanced Science, EarlyView.
An efficient photoinduced and metal‐free method is developed for direct α‐C–H monoalkylation of alcohols utilizing the CO2‐DBU system as the hydrogen bond acceptor (HBA) in the presence of H2O, allowing for selective functionalization of alcohols with a broad substrate scope.
Zeyu Zhang   +5 more
wiley   +1 more source

Solvent Replacement‐Driven Ionic Liquid Thermoelectric Gel for Self‐Powered Morse Code Communication Assisted by Machine Learning

open access: yesAdvanced Science, EarlyView.
A solvent replacement method is employed to transform PMAA hydrogel into a PMAA IL gel. The assembled thermoelectric device demonstrated stable voltage output and temperature sensitivity across a wide operating temperature range. Additionally, a self‐powered communication system integrating the PMAA IL gel with a logistic regression model is developed,
Lingshuang Kong   +4 more
wiley   +1 more source

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