Results 11 to 20 of about 3,908,577 (301)
Frontiers in Immunology, 2021 These last 20 years, research on immune tumor microenvironment led to identify some critical recurrent mechanisms used in cancer to escape immune response. Through immune checkpoints, which are cell surface molecules involved in the immune system control,
Quentin Lemasson +7 more
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Communications Biology, 2022 Regulatory T cells (Tregs) have similar immune profiles in tertiary lymphoid structures of lung cancer and non-TLS areas, with tumor-infiltrating Tregs found to inhibit the proliferation and cytokine secretion of CD4 + conventional T cells.
Priyanka Devi-Marulkar +15 more
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Molecular Cancer, 2023 The malignant tumor is a multi-etiological, systemic and complex disease characterized by uncontrolled cell proliferation and distant metastasis. Anticancer treatments including adjuvant therapies and targeted therapies are effective in eliminating ...
Zhen-Nan Yuan +8 more
semanticscholar +1 more source
SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway
Nature Microbiology, 2022 Vaccines based on the spike protein of SARS-CoV-2 are a cornerstone of the public health response to COVID-19. The emergence of hypermutated, increasingly transmissible variants of concern (VOCs) threaten this strategy. Omicron (B.1.1.529), the fifth VOC
B. Willett +40 more
semanticscholar +1 more source
Cancer Medicine, 2021 Background Epstein‐Barr virus (EBV) is detected in a variety of B‐cell lymphomas (BCLs) and B‐cell lymphoproliferative disorders (B‐LPDs). Immunodeficiency has been considered to play a key role in the pathogenesis of these diseases.
Akira Satou, Shigeo Nakamura
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Frontiers in Immunology, 2023 Glioblastoma is the most common primary malignant tumor of the central nervous system, which has the characteristics of strong invasion, frequent recurrence, and rapid progression.
Hao Liu +19 more
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Timing of immune escape linked to success or failure of vaccination. [PDF]
PLoS ONE, 2010 Successful vaccination against HIV should limit viral replication sufficiently to prevent the emergence of viral immune escape mutations. Broadly directed immunity is likely to be required to limit opportunities for immune escape variants to flourish. We
Jeanette C Reece +9 more
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Molecular Cancer, 2023 Background Targeted drugs are not quite effective for prolonging the survival of patients with gastric cancer due to off-target effects as well as tumor immune escape mechanisms.
Z. Miao +9 more
semanticscholar +1 more source
Cell Communication and Signaling, 2023 Background Breast cancer (BC) is the second most frequent type of cancer in the world and most common among women, configuring a major challenge to global health.
Diandra Zipinotti dos Santos +9 more
semanticscholar +1 more source
Frontiers in Immunology, 2017 Clinical responses to anti-tumor monoclonal antibody (mAb) treatment have been regarded for many years only as a consequence of the ability of mAbs to destroy tumor cells by innate immune effector mechanisms.
Claire Deligne +15 more
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