Results 91 to 100 of about 2,772,829 (401)
Identification of immune infiltration and cuproptosis-related subgroups in Crohn’s disease
Frontiers in Immunology, 2022 Background Crohn’s disease (CD) is a type of heterogeneous, dysfunctional immune-mediated intestinal chronic and recurrent inflammation caused by a variety of etiologies.
Yifan Yuan, M. Fu, Na Li, Mei Ye
semanticscholar +1 more source
Distribution of Tumor-Infiltrating Immune Cells in Glioblastoma [PDF]
CNS Oncology, 2018 Evaluation of features related to infiltrating immune cell level in glioblastoma.Tumor-infiltrating lymphocytes (TILs) through H&E staining, and TILs (CD3, CD4, CD8 and CD20) and macrophage (CD68 and CD163) levels through immunohistochemistry were evaluated through digital analysis.CD68 (9.1%), CD163 (2.2%), CD3 (1.6%) and CD8 (1.6%) had the highest ...
Enrique Orrego +13 more
openaire +3 more sources
Identification of testicular cancer immune infiltrates and novel immune cell subtypes
FEBS Open Bio, 2023 Testicular germ cell tumors (TGCT) are the most common type of testicular cancer, comprising 90–95% of cases and representing the most prevalent solid malignancy in young adult men. Immune infiltrates play important regulatory roles in tumors, but their role in TGCT remains unclear.
Zhiguo Zhu +5 more
openaire +3 more sources
Frontiers in Genetics, 2022 Background: Parkinson’s disease (PD) is a neurodegenerative disease commonly seen in the elderly. On the other hand, cuprotosis is a new copper-dependent type of cell death that can be observed in various diseases.
Songyun Zhao +7 more
semanticscholar +1 more source
Profiling Tumor Infiltrating Immune Cells with CIBERSORT [PDF]
, 2018 Tumor infiltrating leukocytes (TILs) are an integral component of the tumor microenvironment and have been found to correlate with prognosis and response to therapy. Methods to enumerate immune subsets such as immunohistochemistry or flow cytometry suffer from limitations in phenotypic markers and can be challenging to practically implement and ...
Binbin, Chen +4 more
openaire +2 more sources
Immune microenvironment infiltration landscape and immune-related subtypes in prostate cancer
Frontiers in Immunology, 2023 BackgroundThe tumor microenvironment (TME) primarily comprises cancer cells, cancer-infiltrating immune cells, and stromal cells. The tumor cells alter the TME by secreting signaling molecules to induce immune tolerance. The immune cell infiltrating the TME influences the prognosis of patients with cancers.
Wei Wu +10 more
openaire +3 more sources
Cdx2 regulates immune cell infiltration in the intestine [PDF]
Scientific Reports, 2021 AbstractThe intestinal epithelium is a unique tissue, serving both as a barrier against pathogens and to conduct the end digestion and adsorption of nutrients. As regards the former, the intestinal epithelium contains a diverse repertoire of immune cells, including a variety of resident lymphocytes, macrophages and dendritic cells.
Simon Chewchuk +2 more
openaire +3 more sources
Frontiers in Oncology, 2021 Reports indicate that the use of anti-programmed cell death-1 (PD-1) and death ligand-1 (PD-L1) monoclonal antibodies for the treatment of patients diagnosed with melanoma has demonstrated promising efficacy.
Gang Li, Xuran Zhu, Chao Liu
doaj +1 more source
Journal of Inflammation ResearchPurpose Heart failure (HF) remains a leading cause of mortality and morbidity in cardiovascular disease. Research has shown that necroptosis contributes to HF, and immune infiltration has been reported to be implicated in HF.
Yuanting Zhu +6 more
semanticscholar +1 more source
Frontiers in Immunology, 2022 Objective This study aims to identify clinically relevant diagnostic biomarkers in chronic obstructive pulmonary disease (COPD) while exploring how immune cell infiltration contributes towards COPD pathogenesis.
Yuepeng Zhang +9 more
semanticscholar +1 more source