Results 11 to 20 of about 539,258 (257)
Tumor immune microenvironment lncRNAs [PDF]
Briefings in Bioinformatics, 2021 AbstractLong non-coding ribonucleic acids (RNAs) (lncRNAs) are key players in tumorigenesis and immune responses. The nature of their cell type-specific gene expression and other functional evidence support the idea that lncRNAs have distinct cellular functions in the tumor immune microenvironment (TIME).
Eun-Gyeong Park +4 more
openaire +2 more sources
Immune Microenvironment of Thyroid Cancer [PDF]
Journal of Cancer, 2020 Thyroid cancer (TC) is a highly heterogeneous endocrine malignancy with an increased incidence in women than in men. Previous studies regarding the pathogenesis of TC focused on the pathological changes of the tumor cells while ignoring the importance of the mesenchymal cells in tumor microenvironment.
Yin, Hongyu +3 more
openaire +2 more sources
Immune response in glioma’s microenvironment [PDF]
Innovative Surgical Sciences, 2020 Abstract Objectives Glioma is the most common tumor of the central nervous system. In this review, we outline the immunobiological factors that interact with glioma cells and tumor microenvironment (TME), providing more potential targets for clinical inhibition of glioma development and more ...
Chen Houminji +6 more
openaire +3 more sources
Immune microenvironment of gliomas [PDF]
Laboratory Investigation, 2017 High-grade gliomas are rapidly progressing tumors of the central nervous system (CNS) with a very poor prognosis despite extensive resection combined with radiation and/or chemotherapy. Histopathological and flow cytometry analyses of human and rodent experimental gliomas revealed heterogeneity of a tumor and its niche, composed of reactive astrocytes,
Gieryng, Anna +4 more
openaire +2 more sources
Immune Microenvironment in Hematologic Malignancies.
Iranian journal of medical sciences, 2023 The role of the tumor microenvironment (TME), especially immune cell compartments, in tumor progression is inevitable and the heterogeneity and complexity of the TME-associated immune cells make it challenging to provide appropriate treatments for hematologic malignancies.
Arandi, Nargess, Dehghani, Mehdi
openaire +3 more sources
Immune Microenvironment in Glioblastoma Subtypes [PDF]
Frontiers in Immunology, 2018 Glioblastomas (GBMs) are the most common and aggressive primary brain tumors. Due to their malignant growth and invasion into the brain parenchyma coupled with resistance to therapy, GBMs are among the deadliest of all cancers. GBMs are highly heterogeneous at both the molecular and histological levels.
Zhihong Chen, Dolores Hambardzumyan
openaire +3 more sources
Tumor immune microenvironment (TIME) to enhance antitumor immunity
European Journal of Medical Research, 2023 AbstractThe tumor microenvironment is a result of dynamic interaction between different cellular and non-cellular components. In its essence it is not a solo performer, but an ensemble of performers that includes cancer cells, fibroblasts, myo-fibroblasts, endothelial cells and immune cells.
Sajin Rajbhandary +2 more
openaire +3 more sources
The Immune Microenvironment of Myeloma [PDF]
Cancer Microenvironment, 2011 The bone marrow (BM) is the site of disease in myeloma and possesses unique immune characteristics involved in the pathobiology of the disease. Interactions of plasma cells with stromal cells, osteoclasts, osteoblasts, myeloid and lymphoid cells make up the unique bone marrow milieu that mediates myeloma disease progression.
Kimberly, Noonan, Ivan, Borrello
openaire +2 more sources
Vascular Microenvironment, Tumor Immunity and Immunotherapy [PDF]
Frontiers in Immunology, 2021 Immunotherapy holds great promise for treating cancer. Nonetheless, T cell-based immunotherapy of solid tumors has remained challenging, largely due to the lack of universal tumor-specific antigens and an immunosuppressive tumor microenvironment (TME) that inhibits lymphocyte infiltration and activation.
Zachary Lamplugh, Yi Fan
openaire +3 more sources
Pyroptosis, metabolism, and tumor immune microenvironment [PDF]
Clinical and Translational Medicine, 2021 AbstractIn response to a wide range of stimulations, host cells activate pyroptosis, a kind of inflammatory cell death which is provoked by the cytosolic sensing of danger signals and pathogen infection. In manipulating the cleavage of gasdermins (GSDMs), researchers have found that GSDM proteins serve as the real executors and the deterministic ...
Tiantian Du +8 more
openaire +3 more sources