Results 11 to 20 of about 593,447 (356)
Immune Microenvironment in Glioblastoma Subtypes [PDF]
Frontiers in Immunology, 2018 Glioblastomas (GBMs) are the most common and aggressive primary brain tumors. Due to their malignant growth and invasion into the brain parenchyma coupled with resistance to therapy, GBMs are among the deadliest of all cancers. GBMs are highly heterogeneous at both the molecular and histological levels.
Zhihong Chen, Dolores Hambardzumyan
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Tumor immune microenvironment lncRNAs [PDF]
Briefings in Bioinformatics, 2021 AbstractLong non-coding ribonucleic acids (RNAs) (lncRNAs) are key players in tumorigenesis and immune responses. The nature of their cell type-specific gene expression and other functional evidence support the idea that lncRNAs have distinct cellular functions in the tumor immune microenvironment (TIME).
Eun-Gyeong Park +4 more
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Immune Microenvironment of Thyroid Cancer [PDF]
Journal of Cancer, 2020 Thyroid cancer (TC) is a highly heterogeneous endocrine malignancy with an increased incidence in women than in men. Previous studies regarding the pathogenesis of TC focused on the pathological changes of the tumor cells while ignoring the importance of the mesenchymal cells in tumor microenvironment.
Yin, Hongyu +3 more
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Frontiers in Immunology, 2022 B cells, which consist of two well-defined populations: B1 and B2 cells, which can produce antibodies that are essential for host protection against infections, through virus neutralization, opsonization and antibody-dependent cellular cytotoxicity ...
Sulan Zhai +10 more
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Immune response in glioma’s microenvironment [PDF]
Innovative Surgical Sciences, 2020 Abstract Objectives Glioma is the most common tumor of the central nervous system. In this review, we outline the immunobiological factors that interact with glioma cells and tumor microenvironment (TME), providing more potential targets for clinical inhibition of glioma development and more ...
Chen Houminji +6 more
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Journal of Experimental & Clinical Cancer Research, 2023 Background Chronic stress promotes most hallmarks of cancer through impacting the malignant tissues, their microenvironment, immunity, lymphatic flow, etc.
Jun Pan +12 more
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Immune microenvironment of gliomas [PDF]
Laboratory Investigation, 2017 High-grade gliomas are rapidly progressing tumors of the central nervous system (CNS) with a very poor prognosis despite extensive resection combined with radiation and/or chemotherapy. Histopathological and flow cytometry analyses of human and rodent experimental gliomas revealed heterogeneity of a tumor and its niche, composed of reactive astrocytes,
Gieryng, Anna +4 more
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Microorganisms, 2023 Chlamydia trachomatis usually causes mucosal infections, bringing considerable morbidity and socioeconomic burden worldwide. We previously revealed that IL-27/IL-27R mediates protection against chlamydial invasion by promoting a protective Th1 response ...
Jiajia Zeng +9 more
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Immune Microenvironment in Hematologic Malignancies.
Iranian journal of medical sciences, 2023 The role of the tumor microenvironment (TME), especially immune cell compartments, in tumor progression is inevitable and the heterogeneity and complexity of the TME-associated immune cells make it challenging to provide appropriate treatments for hematologic malignancies.
Arandi, Nargess, Dehghani, Mehdi
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Generation of a Murine Model for c-MYC and BCL2 Co-expression B Cell Lymphomas
Frontiers in Oncology, 2020 Diffuse large B-cell lymphoma (DLBCL) is the most frequent lymphoma in adults, and is characterized as clinically and biologically heterogeneous lymphomas with diverse response to therapy and variation in clinical behavior.
Zhenming Cai +9 more
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