Results 21 to 30 of about 792,761 (305)

Vitamin D and immunity [PDF]

open access: yes, 2014
Vitamin D deficiency has been linked to an increased risk of a wide range of adverse health outcomes. The active form of vitamin D has an important role in calcium metabolism and in bone mineralisation, but the evidence for other health outcomes is mixed,
Geldenhuys, Sian   +3 more
core   +1 more source

Immunosuppression factors under various pathologies

open access: yesБюллетень сибирской медицины, 2011
Until recent time it has seemed obvious that suppressive function in the immune system is provided by one subpopulation of Tlymphocytes-suppressors. At present it is usually considered that regulatory cells (T-reg) are key cells-suppressors of the immune
Ye. G. Churina   +2 more
doaj   +1 more source

A Bacterial Quorum Sensing Regulated Protease Inhibits Host Immune Responses by Cleaving Death Domains of Innate Immune Adaptors

open access: yesAdvanced Science, 2023
Innate immune adaptor proteins are critical components of the innate immune system that propagate pro‐inflammatory responses from their upstream receptors, and lead to pathogen clearance from the host.
Xiangke Duan   +12 more
doaj   +1 more source

Multitasking: Making the Most out of the Retroviral Envelope

open access: yesViruses, 2010
Evasion of the host’s immune system is a required step for the establishment of viral infection. In this article, we discuss the recent findings of Heidmann and colleagues demonstrating that some retroviruses possess an immune suppressive (IS) domain ...
Mariana Varela, Massimo Palmarini
doaj   +1 more source

Neutrophils: Musketeers against immunotherapy

open access: yesFrontiers in Oncology, 2022
Neutrophils, the most copious leukocytes in human blood, play a critical role in tumorigenesis, cancer progression, and immune suppression. Recently, neutrophils have attracted the attention of researchers, immunologists, and oncologists because of their
Kashif Rafiq Zahid   +5 more
doaj   +1 more source

Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group. [PDF]

open access: yes, 2017
Cancer immunotherapy has transformed the treatment of cancer. However, increasing use of immune-based therapies, including the widely used class of agents known as immune checkpoint inhibitors, has exposed a discrete group of immune-related adverse ...
Abdallah, K.   +80 more
core   +2 more sources

The role of immune suppression in COVID-19 hospitalization: clinical and epidemiological trends over three years of SARS-CoV-2 epidemic

open access: yesFrontiers in Medicine, 2023
Specific immune suppression types have been associated with a greater risk of severe COVID-19 disease and death. We analyzed data from patients >17 years that were hospitalized for COVID-19 at the “Fondazione IRCCS Ca′ Granda Ospedale Maggiore ...
Marta Canuti   +134 more
doaj   +1 more source

Evaluation of Microparticulate Ovarian Cancer Vaccine via Transdermal Route of Delivery [PDF]

open access: yes, 2016
Ovarian cancer is the fifth most commonly occurring malignancy in women, with the highest mortality rate among all the gynecological tumors. Microparticulate vaccine can serve as an immunotherapeutic approach with a promising antigenic delivery system ...
Akalkotkar, Archana   +3 more
core   +2 more sources

IMMUNE RESPONSE IN MALIGNANT GLIOMA [PDF]

open access: yesJournal of IMAB, 2010
Objective: Malignant gliomas are primary brain tumors with excessive mortality and high resistance to chemotherapy and radiotherapy. The survival time for glioblastoma multi­forme is about 6-12 months.
Iliyan Koev   +4 more
doaj  

TLR7-mediated skin inflammation remotely triggers chemokine expression and leukocyte accumulation in the brain [PDF]

open access: yes, 2016
Background: The relationship between the brain and the immune system has become increasingly topical as, although it is immune-specialised, the CNS is not free from the influences of the immune system.
A Boivin   +53 more
core   +2 more sources

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