Results 31 to 40 of about 2,062,013 (251)

Viral dynamics during structured treatment interruptions of chronic human immunodeficiency virus type 1 infection [PDF]

, 2002
Although antiviral agents which block human immunodeficiency virus (HIV) replication can result in long-term suppression of viral loads to undetectable levels in plasma, long-term therapy fails to eradicate virus, which generally rebounds after a single ...
Ruiz, L, Javier Martinez-Picado, Clotet, B, Frost, SDW, Martinez-Picado, J, Lidia Ruiz, Leigh Brown, AJ, Simon D. W. Frost, Bonaventura Clotet, Andrew J. Leigh Brown   +9 more
core   +1 more source

Isoxazole Derivatives as Regulators of Immune Functions

Molecules, 2018
In this review, we present reports on the immunoregulatory properties of isoxazole derivatives classified into several categories, such as immunosuppressive, anti-inflammatory, immunoregulatory, and immunostimulatory compounds.
Michał Zimecki, Urszula Bąchor, Marcin Mączyński   +2 more
doaj   +1 more source

Reported mechanisms of measles immune suppression.

, 2014
Reported mechanisms of measles immune suppression.
Rory D. de Vries (76306), Rik L. de Swart (76309)   +1 more
core   +1 more source

Concurrent Immune Suppression and Hyperinflammation in Patients With Community-Acquired Pneumonia

Frontiers in Immunology, 2020
BackgroundThe nature and timing of the host immune response during infections remain uncertain and most knowledge is derived from critically ill sepsis patients.
Xanthe Brands, Bastiaan W. Haak, Augustijn M. Klarenbeek, Natasja A. Otto, Daniël R. Faber, René Lutter, Brendon P. Scicluna, Brendon P. Scicluna, W. Joost Wiersinga, W. Joost Wiersinga, Tom van der Poll, Tom van der Poll   +11 more
doaj   +1 more source

Targeting regulatory T cells for immunotherapy in melanoma

Molecular Biomedicine, 2021
Regulatory T cells (Tregs) are essential in the maintenance of immunity, and they are also a key to immune suppressive microenvironment in solid tumors. Many studies have revealed the biology of Tregs in various human pathologies.
Lili Huang, Yeye Guo, Shujing Liu, Huaishan Wang, Jinjin Zhu, Lingling Ou, Xiaowei Xu   +6 more
doaj   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

Syndrome of persistent inflammation, the immune suppression and catabolism in surgery [PDF]

, 2020
Syndrome of persistent inflammation, the immune suppression and catabolism in ...
S. M. Chuklin, S. S. Chuklin, G. V. Shershen, G. V. Shershen, S. S. Chuklin, S. M. Chuklin   +5 more
core   +1 more source

Tumour suppression by Immune System through Stochastic Oscillations

, 2010
The well-known Kirschner–Panetta model for tumour–immune System interplay [Kirschner, D., Panetta, J.C., 1998. Modelling immunotherapy of the tumour–immune interaction. J. Math. Biol.
MILAZZO P, CARAVAGNA G, BARBUTI R, D'ONOFRIO A   +3 more
core   +2 more sources

Microplastics induce immune suppression via S100A8 downregulation

Ecotoxicology and Environmental Safety, 2022
Microplastic (MP) pollution has been largely reported in the daily consumption of water and food, however, the toxicities of MPs to human beings remain largely uncovered. We found that MPs in drinking water significantly impaired mouse immune function by
Juan WANG, Xiaojuan WANG, Conghui ZHANG, Xiao ZHOU   +3 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source