Results 191 to 200 of about 14,479 (218)

Preclinical evaluation of ⁶⁴Cu-labeled cetuximab in immuno-PET for detecting sentinel lymph node metastasis in epidermal growth factor receptor-positive breast cancer. [PDF]

Breast Cancer Res
Usui T, Miyake T, Watabe T, Kato H, Yoshii Y, Naka S, Abe K, Masuyama M, Masunaga N, Yoshinami T, Tsukabe M, Sota Y, Tanei T, Shimoda M, Shimazu K.   +14 more
europepmc   +1 more source

ITGB1 Regulates Triple‐Negative Breast Cancer Development by Modulating the Tumor Microenvironment

Advanced Science, Volume 13, Issue 20, 9 April 2026.
ABSTRACT Tumorigenesis and metastasis are frequently attributed to the intricate interplay between cancer cells and the tumor microenvironment (TME). Comprehending the mechanisms and key regulators of cancer‐immune crosstalk in the TME is imperative for developing efficacious immunotherapy.
Nuozi Song, Siqi Chen, Lei Wang, Jessica Dang, Xu Cao, Stephanie Singh, Lu Yang, Jinhui Wang, Steven T. Rosen, Yingyu Wang, Chun‐Wei D. Chen, Cheng Zhang, Mingye Feng   +12 more
wiley   +1 more source

Peptide-based immuno-PET/CT monitoring of dynamic PD-L1 expression during glioblastoma radiotherapy. [PDF]

J Pharm Anal
Wang Y, He K, Zhang Y, Chen Y, Wang S, Zhao K, Liu Z, Hu M.   +7 more
europepmc   +1 more source

Developmentally Inspired, Mechanical–Metabolic Dual Gradient Osteochondral Constructs Bridging Regeneration and Therapeutic Screening

Advanced Science, Volume 13, Issue 24, 27 April 2026.
A developmentally inspired osteochondral construct integrates mechanical and metabolic dual gradients within a 3D‐printed platform. Human MSC spheroids are spatially directed to form cartilage–bone interfaces, enabling evaluation of regeneration without biochemical reagents and assessment of drug responses. This physiologically relevant, phase‐specific
Yurim Choi, Wonjun Jang, Raehui Kang, Ulziituya Batjargal, Jihyeon Song, Soojin Park, MinSeok Kim, Hyobum Cho, Junhyung Kim, Yu Shrike Zhang, Han‐Jun Kim, Junmin Lee   +11 more
wiley   +1 more source

Tracking tau and cellular responses in human iPSC‐microglia: from uptake to seedable secretion, including in extracellular vesicles

Alzheimer's &Dementia, Volume 22, Issue 4, April 2026.
Abstract INTRODUCTION Microglia have been implicated in the templated spread of tau aggregates in tauopathies through mouse studies. However, it is unclear whether these findings translate to human disease. METHODS We challenged human induced pluripotent stem cell (iPSC)‐derived microglia‐like‐cells (iMGL) with monomeric and fibrillar recombinant tau ...
Maria Kreger Karabova, Anna del Ser‐Badia, Anne Hedegaard, Sam J. Washer, Zeynep Baykam, Darragh P. O'Brien, Iolanda Vendrell, Svenja S. Hester, Roman Fischer, Errin Johnson, Charlotte E. Melia, Teige R. S. Matthews‐Palmer, Rishi Matadeen, Alessia Santambrogio, Michael A. Metrick II, Michele Vendruscolo, Sophie Keeling, Kimberly Ai Xian Cheam, William A. McEwan, Kenneth S. Kosik, Theresa A. Day, William S. James, Sally A. Cowley   +22 more
wiley   +1 more source

Optimizing Systemic Therapy for Advanced Sarcomas: Outcomes With Gemcitabine, Docetaxel, Cisplatin, and Everolimus in a Retrospective Single‐Center Study

Cancer Medicine, Volume 15, Issue 4, April 2026.
Late‐line gemcitabine, docetaxel, cisplatin, and everolimus yield a 45.5% objective response rate and prolonged survival in selected advanced sarcoma subtypes. Prognostic stratification was enhanced by ECOG performance status and lymphocyte‐to‐monocyte ratio, highlighting their potential role in treatment individualization. ABSTRACT Background Advanced
Wen‐Chi Wu, I‐Wei Ho, San‐Chi Chen, Paul Chih‐Hsueh Chen, Po‐Kuei Wu, Chao‐Ming Chen, Hung‐Ta Wu, Chung‐Jung Lin, Ta‐Chung Chao, Chueh‐Chuan Yen   +9 more
wiley   +1 more source

Investigation of the Impact of the H310A FcRn Region Mutation on ⁸⁹Zr-Immuno-PET Brain Imaging with a BBB-Shuttle Anti‑Amyloid Beta Antibody. [PDF]

Mol Imaging Biol
Wuensche TE, Stergiou N, Mes I, Verlaan M, Kooijman EJM, Windhorst AD, Jensen A, Asuni AA, Bang-Andersen B, van Dongen GAMS, Vugts DJ, Beaino W.   +11 more
europepmc   +1 more source

Sustained Belinostat‐Induced Metabolic Response and Tolerability in Heavily Pretreated Relapsed/Refractory Angioimmunoblastic T‐Cell Lymphoma: A Case Report

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Angioimmunoblastic T‐cell lymphoma (AITL), a rare and aggressive subtype of peripheral T‐cell lymphoma (PTCL), often demonstrates resistance to standard therapies. The optimal therapeutic approach for relapsed/refractory (R/R) AITL remains therefore uncertain and challenging, with an unmet need for effective treatment options.
Vassiliki Labropoulou, Evgenia Verigou, Eleni P. Kourea, Maria Liga, Dimitrios Tsokanas, Krisela‐Christina Valera, Alexandros Spyridonidis   +6 more
wiley   +1 more source

A peristaltic pump driven 89Zr separation module [PDF]

, 2012
Ohlsson, T., Peterson, M., Roos, Per, Sandell, A., Siikanen, J., Tran, T.   +5 more
core  

Immature Excitatory Neurons in the Postnatal Ferret Paralaminar Nuclei and Their Relationship to the Amygdala Across Species

Journal of Comparative Neurology, Volume 534, Issue 4, April 2026.
Left: Schematic of a coronal section of the adult ferret brain, showing the location of a collection of Dcx+ cells (green) ventrally to the amygdala (grey) in a region homologous to the PL in other species. These cells are spatially distributed either as individual cells in a dispersed field or in clusters (1). Cells in the ferret PL display molecular (
Lucía Inés Torrijos‐Saiz, Marco Ghibaudi, Malaz Sharief, Lovisa Ljungqvist Brinson, Arturo Alvarez‐Buylla, José Manuel García‐Verdugo, Vicente Herranz‐Pérez, Shawn Sorrells   +7 more
wiley   +1 more source